Immo Burkhardt
@immo-burkhardt.bsky.social
Asst. Project Scientist at Scripps Institution of Oceanography.
Interested in isoprenoid metabolism across the tree of life.
Interested in isoprenoid metabolism across the tree of life.
Reposted by Immo Burkhardt
🧪 #evosky
Great article by @philipcball.bsky.social about recent work on LUCA, quoting Tim Lenton and UIUC alum Rika Anderson. Glad to see mention of early horizontal gene transfer as a driver of evolution.
www.theguardian.com/science/2025...
Great article by @philipcball.bsky.social about recent work on LUCA, quoting Tim Lenton and UIUC alum Rika Anderson. Glad to see mention of early horizontal gene transfer as a driver of evolution.
www.theguardian.com/science/2025...
Luca is the progenitor of all life on Earth. But its genesis has implications far beyond our planet
New research into the single-celled organism is providing clues about what the early planet looked like – and raising the prospect that we may not be alone in the universe
www.theguardian.com
January 19, 2025 at 6:38 PM
🧪 #evosky
Great article by @philipcball.bsky.social about recent work on LUCA, quoting Tim Lenton and UIUC alum Rika Anderson. Glad to see mention of early horizontal gene transfer as a driver of evolution.
www.theguardian.com/science/2025...
Great article by @philipcball.bsky.social about recent work on LUCA, quoting Tim Lenton and UIUC alum Rika Anderson. Glad to see mention of early horizontal gene transfer as a driver of evolution.
www.theguardian.com/science/2025...
Reposted by Immo Burkhardt
We are excited to see our review published! In it, we explore the diversity of enzymatic strategies for installing aromatic side chain cross-links in RiPPs. If you like interesting chemistry and new enzyme reactions, be sure to check it out!
A Review from Sanath Kandy, Michael Pasquale, and Jonathan Chekan highlights newly discovered enzymes responsible for aromatic side-chain crosslinking in ribosomally synthesized and post-translationally modified peptides (RiPPs)
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Aromatic side-chain crosslinking in RiPP biosynthesis - Nature Chemical Biology
Aromatic side-chain crosslinking is emerging as a widespread and biosynthetically diverse feature in the RiPP natural products. This Review summarizes and unifies recent advancements, focusing on key ...
www.nature.com
January 16, 2025 at 6:30 PM
We are excited to see our review published! In it, we explore the diversity of enzymatic strategies for installing aromatic side chain cross-links in RiPPs. If you like interesting chemistry and new enzyme reactions, be sure to check it out!
Reposted by Immo Burkhardt
What makes AetF the most efficient flavin-dependent halogenase discovered to date? Prof. Pimchai Chaiyen and Dr. Aisaraphon Phintha decode the mechanistic principles of flavin chemistry in AetF in our new study out in PNAS: www.pnas.org/doi/epub/10....
#halogenases #biocatalysis
#halogenases #biocatalysis
www.pnas.org
January 13, 2025 at 6:29 PM
What makes AetF the most efficient flavin-dependent halogenase discovered to date? Prof. Pimchai Chaiyen and Dr. Aisaraphon Phintha decode the mechanistic principles of flavin chemistry in AetF in our new study out in PNAS: www.pnas.org/doi/epub/10....
#halogenases #biocatalysis
#halogenases #biocatalysis
Reposted by Immo Burkhardt
For our first post, it is my great pleasure to announce our new publication in Nature, where we elucidate interactions for peptide elongation in non-ribosomal peptide synthetases! Congratulations to Graham Heberlig on this major achievement! www.nature.com/articles/s41...
Crosslinking intermodular condensation in non-ribosomal peptide biosynthesis - Nature
Structural studies of tyrocidine synthetase using site-selective crosslinking probes to link condensation domains with carrier protein substrates define key interactions and molecular mechanisms of no...
www.nature.com
December 11, 2024 at 5:17 PM
For our first post, it is my great pleasure to announce our new publication in Nature, where we elucidate interactions for peptide elongation in non-ribosomal peptide synthetases! Congratulations to Graham Heberlig on this major achievement! www.nature.com/articles/s41...
Reposted by Immo Burkhardt
Today we report that an engineered skin bacterium, swabbed gently on the head of a mouse, can unleash a potent antibody response against a pathogen. Could lead to topical vaccines that are applied in a cream. @djenetbousbaine.bsky.social led the charge... @natureportfolio.bsky.social 1/55
December 11, 2024 at 4:29 PM
Today we report that an engineered skin bacterium, swabbed gently on the head of a mouse, can unleash a potent antibody response against a pathogen. Could lead to topical vaccines that are applied in a cream. @djenetbousbaine.bsky.social led the charge... @natureportfolio.bsky.social 1/55