We don’t get into that in the article. But two level will work

however, this is far from clinically feasible."

"for the individual patient, a trough of 12 mg/L is expected to result in AUCs that range from 260.0 to 558.3 mg/L × 24 hours in 95% of cases. Thus, trough concentration monitoring may be appropriate if clinicians are able to maintain troughs within a range of ±1 mg/L; ...

Similar. All we know is the blackout time. What happens next? Anyone's guess. :(

All I can say is that the experience that others have reported (cancellations - ?temporary?) appears to be playing out. Even a pause is significant. We all now wait to find out what is next.

Here is a quick note on why this was a bittersweet publication from the lab.

www.linkedin.com/posts/jack-c...

This is the most comprehensive report on the status quo that I have seen: www.science.org/content/arti...

Is there an official report of this? It would be devastating. I have not seen indication of this for upcoming activities that I am involved with. Hoping it is a "misread".

I too am really interested in where this information is coming from. I have not heard that our upcoming study section is cancelled. There are pre-meetings scheduled next week. Hoping that it does not come to bear.