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IDMD
@idmdtdi.bsky.social
HBV Prophylaxis in at risk pts----credit to AGA clinical practice guideline on the prevention and treatment of hepatitis B virus reactivation in at-risk individuals (Gastroenterology 2025;168:267-284)
February 14, 2025 at 12:49 AM
www.health.ny.gov/press/releas... Re: mpox in NYC: 'There are no reported links between either the Georgia or New
Hampshire case with the New York case'... #idsky
At present the risk to the public is low and there are no additional known community cases of mpox clade Ib.
www.health.ny.gov
February 13, 2025 at 3:35 PM
What about this new proposed algorithm (4th gen HIV Ag/Ab then HIV-1,-2 qualitative NAT) ? Will still detect acute infection as current algorithm and quickly identify false positive 4th gen HIV tests....
Estimating the economic consequences of leveraging the novel cobas® HIV-1/HIV-2 Qualitative NAT Test in routine HIV testing
This research conveys the modeled economic consequences of using novel cobas® HIV-1/HIV-2 Qualitative NAT Test as an alternative option relative to the cur
academic.oup.com
February 2, 2025 at 7:09 PM
Jeez----https://apnews.com/article/trump-health-communications-cdc-hhs-fda-1eeca64c1ccc324b31b779a86d3999a4

'pause on regulations, guidance, announcements, press releases, social media posts and website posts until such communications had been approved by a political appointee' #idsky
January 22, 2025 at 9:35 PM
We must continue to find undiagnosed cases of HIV and get folks into care...
HRSA HIV/AIDS Bureau Update: Special Bulletin
Cross-posted from: TargetHIV (PDF, 294KB) On December 20, 2024, the Health Resources and Services Administratio...
www.hiv.gov
January 3, 2025 at 7:04 PM
Read NYT for H5N1 Updates? It is not clear how the patient in Louisiana is faring. A spokeswoman for the LA Department of Health declined on Fri to answer questions about the person’s condition. It is also not clear when in the course of the patient’s hospitalization the swabs were taken. #idsky
Bird Flu Samples From Very Ill Patient Had ‘Concerning’ Mutations
Tiny genetic alterations could help the bird flu virus enter cells in the upper respiratory tract, the C.D.C. said. But there is no sign that mutations are widespread in nature.
www.nytimes.com
December 28, 2024 at 4:18 AM
How do syphilis POC tests differ from laboratory-based serologic syphilis tests?
-Uses whole blood
-Results in 15 min
-Used as an initial screening test or in conj w a non-treponemal laboratory test + clinical findings to aid in the dx of syphilis inf.
-Have lower sensi/specif
#idsky #syphilis
www.hhs.gov
December 28, 2024 at 4:09 AM
Tpox can be accessed thru the CDC’s EA-IND for patients who meet criteria that include those who:
• Are severely immunocompromised
• Have life-threatening mpox symptoms
• Have specific skin conditions
• Are pregnant, breastfeeding, or younger than 18 years of age
www.nyc.gov
December 28, 2024 at 4:02 AM
Tpoxx safe but didn't improve mpox resolution or pain #idsky end of STOMPP
NIH Study Finds Tecovirimat Was Safe but Did Not Improve Mpox Resolution or Pain
Tecovirimat was safe but did not reduce the time to lesion resolution or reduce pain among adults with mild to moderate clade II mpox and a low risk of severe disease in an international study.
www.niaid.nih.gov
December 10, 2024 at 8:13 PM
The 2025 Immunization Schedules approved by ACIP and adopted by the CDC Director on October 24, 2024

#idsky

www.cdc.gov/vaccines/hcp...
Immunization Schedules
Make sure your patients stay up to date on recommended vaccines using these schedules.
www.cdc.gov
December 10, 2024 at 6:41 PM
"Currently lenacapavir costs $25 395–44 819 pppy (person per year)"
#idsky
Lenacapavir could be mass produced for <$100 pppy at launch.... To date, Gilead has not agreed lenacapavir voluntary licences with the Medicines Patent Pool.
doi.org/10.1093/jac/...
Lenacapavir to prevent HIV infection: current prices versus estimated costs of production
AbstractBackground. Despite improvements in treatment and oral pre-exposure prophylaxis (PrEP) access, 1.3 million people acquired HIV in 2022. Six-monthly
doi.org
December 10, 2024 at 2:46 AM
Box 3 in the 2024 Recommendations of the International Antiviral Society–USA Panel
(much better format than the DHHS Guidelines!) #idsky

Gandhi RT, Landovitz RJ, Sax PE, et al. doi:10.1001/jama.2024.24543 #hivsky
December 10, 2024 at 2:26 AM
www.regulations.gov/docket/CDC-2...

CDC is requesting input about HIV screening in clinical settings; I say go all out on true opt out testing!
Regulations.gov
www.regulations.gov
December 4, 2024 at 11:26 PM