Ian Copple
@iancopple.bsky.social
MRC Senior Fellow, Professor of Pharmacology & Toxicology, University of Liverpool. Leading the Stress Response Lab (www.liverpool.ac.uk/stress-response-lab) and Human Liver Research Facility (www.liverpool.ac.uk/hlrf).
Pinned
Ian Copple
@iancopple.bsky.social
· Nov 18
Here's a starter pack to make it easy to follow life science researchers based at the University of Liverpool.
A great way to expand our networks. Get in touch if you want to be added!
go.bsky.app/Fk7bp3g
A great way to expand our networks. Get in touch if you want to be added!
go.bsky.app/Fk7bp3g
📢 Fully funded PhD opportunity in my group!
Project title: Unravelling the origins, mechanisms and implications of species differences in cellular stress response pathway capacities.
Application deadline: 7 December 2025.
Details/apply: tinyurl.com/2jcp9jfz
Questions: Get in touch!
Project title: Unravelling the origins, mechanisms and implications of species differences in cellular stress response pathway capacities.
Application deadline: 7 December 2025.
Details/apply: tinyurl.com/2jcp9jfz
Questions: Get in touch!
(BBSRC NWD CASE) Unravelling the origins, mechanisms and implications of species differences in cellular stress response pathway capacities at University of Liverpool on FindAPhD.com
PhD Project - (BBSRC NWD CASE) Unravelling the origins, mechanisms and implications of species differences in cellular stress response pathway capacities at University of Liverpool, listed on FindAPhD...
tinyurl.com
November 11, 2025 at 9:37 PM
📢 Fully funded PhD opportunity in my group!
Project title: Unravelling the origins, mechanisms and implications of species differences in cellular stress response pathway capacities.
Application deadline: 7 December 2025.
Details/apply: tinyurl.com/2jcp9jfz
Questions: Get in touch!
Project title: Unravelling the origins, mechanisms and implications of species differences in cellular stress response pathway capacities.
Application deadline: 7 December 2025.
Details/apply: tinyurl.com/2jcp9jfz
Questions: Get in touch!
Earlier this month I had a fantastic time in Galway, Ireland attending the SFRRI biennial meeting and the @benbedphar.bsky.social satellite meeting. Nice to catch up with friends and colleagues, including the 'Godfather' of the NRF2 field Masi Yamamoto!
June 19, 2025 at 12:29 PM
Earlier this month I had a fantastic time in Galway, Ireland attending the SFRRI biennial meeting and the @benbedphar.bsky.social satellite meeting. Nice to catch up with friends and colleagues, including the 'Godfather' of the NRF2 field Masi Yamamoto!
Reposted by Ian Copple
Outstanding talk by @parikki.bsky.social , recipient of the CATHERINE PASQUIER AWARD LECTURE at SFFR-I Biennial Meeting in Galway @uniofgalway.bsky.social.
Are ROS generated in nanodomains / condensates in cells?
Want to know more, please read her paper
lnkd.in/dq_6Rnaw
@sfrre-ecr.bsky.social
Are ROS generated in nanodomains / condensates in cells?
Want to know more, please read her paper
lnkd.in/dq_6Rnaw
@sfrre-ecr.bsky.social
June 6, 2025 at 11:11 AM
Outstanding talk by @parikki.bsky.social , recipient of the CATHERINE PASQUIER AWARD LECTURE at SFFR-I Biennial Meeting in Galway @uniofgalway.bsky.social.
Are ROS generated in nanodomains / condensates in cells?
Want to know more, please read her paper
lnkd.in/dq_6Rnaw
@sfrre-ecr.bsky.social
Are ROS generated in nanodomains / condensates in cells?
Want to know more, please read her paper
lnkd.in/dq_6Rnaw
@sfrre-ecr.bsky.social
Liverpool's @parikki.bsky.social giving the Catherine Pasquier Award lecture at the SFRRI Biennial Meeting in Galway. Fantastic talk 👏🏻
@liverpooluni.bsky.social @livuni-ismib.bsky.social
@livunihls.bsky.social
@liverpooluni.bsky.social @livuni-ismib.bsky.social
@livunihls.bsky.social
June 6, 2025 at 10:09 AM
Liverpool's @parikki.bsky.social giving the Catherine Pasquier Award lecture at the SFRRI Biennial Meeting in Galway. Fantastic talk 👏🏻
@liverpooluni.bsky.social @livuni-ismib.bsky.social
@livunihls.bsky.social
@liverpooluni.bsky.social @livuni-ismib.bsky.social
@livunihls.bsky.social
A huge well done to group member Hannah Coghlan for passing her PhD viva today. It's been a pleasure to work with Hannah over the past 4 years, she deserves all of her success. Congratulations Dr Coghlan 🍾🎉👏🏻
May 13, 2025 at 1:42 PM
A huge well done to group member Hannah Coghlan for passing her PhD viva today. It's been a pleasure to work with Hannah over the past 4 years, she deserves all of her success. Congratulations Dr Coghlan 🍾🎉👏🏻
Big congratulations to group member Hannah Coghlan for winning a poster prize at the British Toxicology Society annual meeting. Very well done 👏🏻
May 9, 2025 at 1:06 PM
Big congratulations to group member Hannah Coghlan for winning a poster prize at the British Toxicology Society annual meeting. Very well done 👏🏻
Fantastic presentation from group member Olivia Harris as part of the selected oral communications session at the British Toxicology Society annual congress.
May 8, 2025 at 2:01 PM
Fantastic presentation from group member Olivia Harris as part of the selected oral communications session at the British Toxicology Society annual congress.
After months of preparation, we're finally ready to kick off the British Toxicology Society annual congress in Liverpool. Thanks to the rest of the organising committee for making this possible. Looking forward to a great meeting!
May 7, 2025 at 9:47 AM
After months of preparation, we're finally ready to kick off the British Toxicology Society annual congress in Liverpool. Thanks to the rest of the organising committee for making this possible. Looking forward to a great meeting!
Coming to the end of a fantastic few days in Rome participating in the @benbedphar.bsky.social meeting at Sapienza University. Great discussions about progress and next steps for NRF2 pharmacology. Managed to squeeze in a Parkrun too! 🏃🏻♂️
February 22, 2025 at 10:17 AM
Coming to the end of a fantastic few days in Rome participating in the @benbedphar.bsky.social meeting at Sapienza University. Great discussions about progress and next steps for NRF2 pharmacology. Managed to squeeze in a Parkrun too! 🏃🏻♂️
Reposted by Ian Copple
New Centre for Excellence in Regulatory Science and Innovation in #Pharmacogenomics to help UK move towards personalised prescribing:
news.liverpool.ac.uk/2025/01/28/n...
@livunihls.bsky.social @livuni-ismib.bsky.social @innovateuk.bsky.social @ukri.org
news.liverpool.ac.uk/2025/01/28/n...
@livunihls.bsky.social @livuni-ismib.bsky.social @innovateuk.bsky.social @ukri.org
January 28, 2025 at 12:00 PM
New Centre for Excellence in Regulatory Science and Innovation in #Pharmacogenomics to help UK move towards personalised prescribing:
news.liverpool.ac.uk/2025/01/28/n...
@livunihls.bsky.social @livuni-ismib.bsky.social @innovateuk.bsky.social @ukri.org
news.liverpool.ac.uk/2025/01/28/n...
@livunihls.bsky.social @livuni-ismib.bsky.social @innovateuk.bsky.social @ukri.org
Nice to catch up as a group over lunch. Some great restaurant deals in January 😄
January 17, 2025 at 2:01 PM
Nice to catch up as a group over lunch. Some great restaurant deals in January 😄
Reposted by Ian Copple
Are you a parent? Or caring for another adult, relative, friend? And are you a UK-based #academic? 🧪
We recently ran a survey (www.qualtrics.manchester.ac.uk/jfe/form/SV_...) to capture lived experiences - if you didn't complete the survey at the time, please do now. Please share w/ colleagues
We recently ran a survey (www.qualtrics.manchester.ac.uk/jfe/form/SV_...) to capture lived experiences - if you didn't complete the survey at the time, please do now. Please share w/ colleagues
Carers in STEMM: Caring Responsibilities
Are you a UK-based academic or student balancing your role as a caregiver with your research? We want to hear your lived experiences!
www.qualtrics.manchester.ac.uk
January 15, 2025 at 10:19 AM
Are you a parent? Or caring for another adult, relative, friend? And are you a UK-based #academic? 🧪
We recently ran a survey (www.qualtrics.manchester.ac.uk/jfe/form/SV_...) to capture lived experiences - if you didn't complete the survey at the time, please do now. Please share w/ colleagues
We recently ran a survey (www.qualtrics.manchester.ac.uk/jfe/form/SV_...) to capture lived experiences - if you didn't complete the survey at the time, please do now. Please share w/ colleagues
Reposted by Ian Copple
✨ Happy New Year! ✨ We hope your 2025 has got off to a fantastic start! To help you plan for the year ahead, we've compiled some key dates for your diary: www.bps.ac.uk/news/article... 🧪💊🗓
#Pharmacology #ClinicalPharmacology #Pharmacogenomics #STEM #STEMEvents
#Pharmacology #ClinicalPharmacology #Pharmacogenomics #STEM #STEMEvents
January 9, 2025 at 4:27 PM
✨ Happy New Year! ✨ We hope your 2025 has got off to a fantastic start! To help you plan for the year ahead, we've compiled some key dates for your diary: www.bps.ac.uk/news/article... 🧪💊🗓
#Pharmacology #ClinicalPharmacology #Pharmacogenomics #STEM #STEMEvents
#Pharmacology #ClinicalPharmacology #Pharmacogenomics #STEM #STEMEvents
Reposted by Ian Copple
Delighted to finally share our latest preprint on the role of NF-kappaB in hypoxia. Quite a few surprises!! www.biorxiv.org/content/10.1...
Have a look!
Have a look!
NF-κB is a Central Regulator of Hypoxia-Induced Gene Expression
Hypoxia is both a physiological and pathological signal in cells. Changes in gene expression play a critical role in the cellular response to hypoxia, enabling cells to adapt to reduced oxygen availab...
www.biorxiv.org
January 9, 2025 at 10:57 AM
Delighted to finally share our latest preprint on the role of NF-kappaB in hypoxia. Quite a few surprises!! www.biorxiv.org/content/10.1...
Have a look!
Have a look!
As a recent recipient of this funding, I can highly recommend it as a means of broadening experiences and networks to support current and future research.
We’ve launched the Cross-Sector Experience Awards, a six-figure fund designed to break down barriers between sectors & accelerate health innovation.
With grants of up to £100k, we’re helping talented individuals gain transformative experiences.
Read more: ow.ly/VsEc50Upk0m
#Grants #LifeSciences
With grants of up to £100k, we’re helping talented individuals gain transformative experiences.
Read more: ow.ly/VsEc50Upk0m
#Grants #LifeSciences
December 12, 2024 at 9:37 AM
As a recent recipient of this funding, I can highly recommend it as a means of broadening experiences and networks to support current and future research.
Reposted by Ian Copple
Have you heard about TherEx, #LivUni's Centre for Experimental Therapeutics?
The TherEx mission is to improve health and wellbeing by optimising the use of existing drugs and accelerating the development of new treatments.
Making medicines better.
➡️ www.liverpool.ac.uk/centre-for-e...
The TherEx mission is to improve health and wellbeing by optimising the use of existing drugs and accelerating the development of new treatments.
Making medicines better.
➡️ www.liverpool.ac.uk/centre-for-e...
December 5, 2024 at 11:06 AM
Have you heard about TherEx, #LivUni's Centre for Experimental Therapeutics?
The TherEx mission is to improve health and wellbeing by optimising the use of existing drugs and accelerating the development of new treatments.
Making medicines better.
➡️ www.liverpool.ac.uk/centre-for-e...
The TherEx mission is to improve health and wellbeing by optimising the use of existing drugs and accelerating the development of new treatments.
Making medicines better.
➡️ www.liverpool.ac.uk/centre-for-e...
Nice Christmas lunch combining with several @livunihls.bsky.social groups. And yes, I know it's not even December yet!
November 28, 2024 at 4:39 PM
Nice Christmas lunch combining with several @livunihls.bsky.social groups. And yes, I know it's not even December yet!
Fully funded MRC DiMeN PhD studentship available in my group starting October 2025. Come work with us in Liverpool!
Identification of accessible biomarkers reflecting drug stimulation of the NRF2 antioxidant pathway in humans
Deadline 13 December 2024
Informal enquiries welcome
Details here...
Identification of accessible biomarkers reflecting drug stimulation of the NRF2 antioxidant pathway in humans
Deadline 13 December 2024
Informal enquiries welcome
Details here...
MRC DiMeN Doctoral Training Partnership: Identification of accessible biomarkers reflecting drug stimulation of the NRF2 antioxidant pathway in humans at University of Liverpool on FindAPhD.com
PhD Project - MRC DiMeN Doctoral Training Partnership: Identification of accessible biomarkers reflecting drug stimulation of the NRF2 antioxidant pathway in humans at University of Liverpool, listed ...
www.findaphd.com
November 27, 2024 at 11:14 AM
Fully funded MRC DiMeN PhD studentship available in my group starting October 2025. Come work with us in Liverpool!
Identification of accessible biomarkers reflecting drug stimulation of the NRF2 antioxidant pathway in humans
Deadline 13 December 2024
Informal enquiries welcome
Details here...
Identification of accessible biomarkers reflecting drug stimulation of the NRF2 antioxidant pathway in humans
Deadline 13 December 2024
Informal enquiries welcome
Details here...
Registration and abstract submission now open for the 2025 British Toxicology Society annual congress. Student and carer bursaries also available. Join us in May for a great meeting in Liverpool!
www.thebts.org/events/bts-a...
www.thebts.org/events/bts-a...
November 26, 2024 at 11:16 AM
Registration and abstract submission now open for the 2025 British Toxicology Society annual congress. Student and carer bursaries also available. Join us in May for a great meeting in Liverpool!
www.thebts.org/events/bts-a...
www.thebts.org/events/bts-a...
I'm looking forward to hosting this online meeting in January. Some great speakers lined up. Still a few days to submit abstracts and plenty of time to register.
my.bps.ac.uk/events/detai...
my.bps.ac.uk/events/detai...
November 24, 2024 at 10:09 AM
I'm looking forward to hosting this online meeting in January. Some great speakers lined up. Still a few days to submit abstracts and plenty of time to register.
my.bps.ac.uk/events/detai...
my.bps.ac.uk/events/detai...
Are you developing in vitro human liver models? Great! But be careful using paracetamol (acetaminophen) as a reference hepatotoxin - see our new article in Tox Sci for the details. Led by former PhD student Lucia Livoti.
#LiverSky
academic.oup.com/toxsci/advan...
#LiverSky
academic.oup.com/toxsci/advan...
Limitations of acetaminophen as a reference hepatotoxin for the evaluation of in vitro liver models
Abstract. Acetaminophen is commonly used as a reference hepatotoxin to demonstrate that in vitro human liver platforms can emulate features of clinical dru
academic.oup.com
November 21, 2024 at 7:30 AM
Are you developing in vitro human liver models? Great! But be careful using paracetamol (acetaminophen) as a reference hepatotoxin - see our new article in Tox Sci for the details. Led by former PhD student Lucia Livoti.
#LiverSky
academic.oup.com/toxsci/advan...
#LiverSky
academic.oup.com/toxsci/advan...
The Human Liver Research Facility here in Liverpool offers fresh & cryopreserved primary liver cells in 2D & 3D, precision cut liver slices, tissue (including perfusion soon) to academic, industry and commercial partners. Plus donor matched blood.
More details: www.liverpool.ac.uk/hlrf
#LiverSky
More details: www.liverpool.ac.uk/hlrf
#LiverSky
November 19, 2024 at 9:25 PM
The Human Liver Research Facility here in Liverpool offers fresh & cryopreserved primary liver cells in 2D & 3D, precision cut liver slices, tissue (including perfusion soon) to academic, industry and commercial partners. Plus donor matched blood.
More details: www.liverpool.ac.uk/hlrf
#LiverSky
More details: www.liverpool.ac.uk/hlrf
#LiverSky
Here's a starter pack to make it easy to follow life science researchers based at the University of Liverpool.
A great way to expand our networks. Get in touch if you want to be added!
go.bsky.app/Fk7bp3g
A great way to expand our networks. Get in touch if you want to be added!
go.bsky.app/Fk7bp3g
November 18, 2024 at 10:38 PM
Here's a starter pack to make it easy to follow life science researchers based at the University of Liverpool.
A great way to expand our networks. Get in touch if you want to be added!
go.bsky.app/Fk7bp3g
A great way to expand our networks. Get in touch if you want to be added!
go.bsky.app/Fk7bp3g
Hello! We're an academic research group based at the University of Liverpool, UK.
We're interested in the pharmacology and toxicology of stress response pathways. Particularly the NRF2 oxidative stress response.
See here for more details www.liverpool.ac.uk/people/ian-c...
We're interested in the pharmacology and toxicology of stress response pathways. Particularly the NRF2 oxidative stress response.
See here for more details www.liverpool.ac.uk/people/ian-c...
November 18, 2024 at 7:04 PM
Hello! We're an academic research group based at the University of Liverpool, UK.
We're interested in the pharmacology and toxicology of stress response pathways. Particularly the NRF2 oxidative stress response.
See here for more details www.liverpool.ac.uk/people/ian-c...
We're interested in the pharmacology and toxicology of stress response pathways. Particularly the NRF2 oxidative stress response.
See here for more details www.liverpool.ac.uk/people/ian-c...