Scott Wrigley
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Scott Wrigley
@i-scott-this.bsky.social
PhD Student @ Colorado State. I work to unravel how the gut microbiome influences host health. My research is driven by a curiosity about how lifestyle factors—such as diet, environment, and physical activity—interact with host microbiomes.
Dr. Kathy Lozupone presenting on the impact of diet on health outcomes in HIV.

#CIMM2025
March 12, 2025 at 7:04 PM
Colorado State Microbiome Network Co-Director Dr. Jessica Metcalf presenting on the microbial ecology of decomposition #CIMM2025 #CoSMic #GRAM
March 12, 2025 at 6:40 PM
Dr. Brookie Best presenting on the #microbiome research being conducted at the Skaggs School of Pharmacy

#CIMM2025
March 12, 2025 at 5:03 PM
Kicking off Day 2 at the Center for Microbiome Innovation International Microbiome Conference with a talk from @johandelsman.bsky.social

#CIMM2025
March 12, 2025 at 4:15 PM
New research from my #GRAM colleague Sylvia Lee and mentor Sarah Ardanuy Johnson, PhD RDN, out of the Department of Food Science and Human Nutrition at Colorado State University.

The crossover study examined the feasibility and tolerability of daily consumption of #microgreens over two weeks.
New #research alert!

#GRAM member Sylvia Lee and a team led by Sarah Ardanuy Johnson, PhD RDN, tested the feasibility and tolerability of consuming microgreens daily—and it turns out they may not just be a trendy garnish! 🌱

Read more about the study below!
February 4, 2025 at 1:06 AM
I am looking forward to the start of the CSU Microbiome Network seminar series tomorrow and hearing Dr. Claire de La Serre's insights on the impact of diet and the gut microbiome on vagal signaling.

#GutMicrobiome #MicrobiomeScience
We are looking forward to tomorrow's start of the Spring CSU Microbiome Network seminar series. Tomorrow's speaker, Claire de La Serre, PhD, works on identifying mechanisms by which diet affects vagal sensory neurons signaling, in particular diet-driven alterations in microbiota composition.
January 28, 2025 at 2:01 PM
@gram-csu.bsky.social members are excited to hear the student's choice keynote, Dr. Thea Whitman @theawhitman.bsky.social, at this year's Front Range Microbiome Symposium! With more participants than ever, #FRMS2025 is a hotbed of the latest scientific #research and innovation in #MicrobiomeScience.
The Front Range Microbiome Symposium is back as a 2-day event!

📆 April 24: 1/2 day for early-career researchers
📆 April 25: Full-day symposium w/ keynotes:

🎤Dr. Thea Whitman
🎤Dr. Claudia Gunsch
🎤Dr. Gautam Dantas

📍 CSU Spur Campus, Denver, CO

🖋️ tinyurl.com/FRMS2025
#FRMS2025 #Microbiomes #CoSMic
Registration
Click here to register for FRMS 2025! To be considered for either an oral or poster presentation, you must register with an accompanying abstract by end of day Saturday, February 15th. You are not …
tinyurl.com
January 21, 2025 at 3:38 AM
Reposted by Scott Wrigley
🌱 How do plants select their microbial allies? A new review discusses how wild plants evolve to recruit microbes, boosting resilience. Domesticated crops often lose this trait, but breeding strategies could restore it for better sustainability. Read more: tinyurl.com/ycxbr226 #PlantMicrobiome
Microbiome selection and evolution within wild and domesticated plants
Microbes are ubiquitously found across plant surfaces and even within their cells, forming the plant microbiome. Many of these microbes contribute to the functioning of the host and consequently affect its fitness. Therefore, in many contexts, including microbiome effects enables a better understanding of the phenotype of the plant rather than considering the genome alone. Changes in the microbiome composition are also associated with changes in the functioning of the host, and there has been considerable focus on how environmental variables regulate plant microbiomes. More recently, studies suggest that the host genome also preconditions the microbiome to the environment of the plant, and the microbiome is therefore subject to evolutionary forces. Here, we outline how plant microbiomes are governed by both environmental variables and evolutionary processes and how they can regulate plant health together.
tinyurl.com
January 6, 2025 at 5:11 PM
Reposted by Scott Wrigley
A study in Nutrition Research found a low-dose fiber supplement (12 grams/day) reduced LBP levels (a gut permeability marker) in young adults with elevated baseline LBP levels consuming a low-fiber diet.

www.sciencedirect.com/science/arti...

#GutHealth #Microbiome #Prebiotics #NutritionResearch
Polyphenols have unique cellular effects that are distinct from antioxidant function in Toll-like receptor 4–mediated inflammation in RAW264.7 macrophage-like cells
Plant polyphenols are bioactive compounds touted for their antioxidant effects, and this is often the primary attribute used to explain their health b…
www.sciencedirect.com
December 30, 2024 at 5:10 PM
Reposted by Scott Wrigley
This is the right move and others should follow the lead. Many of these journals favor article fees over peer review. “A committee of scholars in Finland has decided to downgrade 271 journals from Frontiers and MDPI in their quality rating system” retractionwatch.com/2024/12/24/f...
Finland Publication Forum will downgrade hundreds of Frontiers and MDPI journals
A committee of scholars in Finland has decided to downgrade 271 journals from Frontiers and MDPI in their quality rating system, in a move that may discourage researchers from submitting manuscript…
retractionwatch.com
December 29, 2024 at 9:04 PM
Reposted by Scott Wrigley
☕This year, in our #CellDeath focus:
Man & Kanneganti reviewed how pattern-recognition sensors in innate #ImmuneCells recognize and respond to cell-death signatures, and highlight molecular targets for potential therapeutic development.
👉https://rdcu.be/d4uDO
www.nature.com/articles/s41...
Innate immune sensing of cell death in disease and therapeutics - Nature Cell Biology
Man and Kanneganti discuss how pattern-recognition sensors in innate immune cells recognize and respond to cell-death signatures, and highlight molecular targets for potential therapeutic development.
www.nature.com
December 22, 2024 at 4:33 PM
Reposted by Scott Wrigley
Exciting Opportunity in Gut Microbiome Research!

The Lozupone Lab at CU Anschutz is hiring a Research Professional! Their lab explores how the gut microbiome influences diseases like HIV and C. difficile infection, while also running a sequencing core.

www.linkedin.com/jobs/view/41...
www.linkedin.com
December 21, 2024 at 6:07 AM
New research from our lab!

Led by Bri Risk and Colorado State Microbiome Network Co-Director Tiffany Weir, the project explored the impact of Bacillus subtilis DE111 on blood vessel function in western diet-fed mice. DOI: 10.1163/18762891-bja00052

#CoSMic #GRAM #GutMicrobiome #CVD #HostMicrobiome
New research from the #CoSMic Network exploring how the probiotic Bacillus subtilis DE111 affects blood vessel function in western diet-fed mice. Published in Beneficial Microbes, this study highlights the potential of microbiome-targeted therapies on vessel function!

DOI: 10.1163/18762891-bja00052
December 14, 2024 at 2:59 AM
Reposted by Scott Wrigley
Innovation thrives when disciplines unite. Within the #CoSMic Network & #GRAM, interdisciplinary collaboration drives our mission to tackle microbiome challenges and advance science for a healthier world.

communities.springernature.com/posts/collab...

#Microbiome #Science #Collaboration
Collaborative science bridges tiny streams and massive rivers, by connecting molecular processes to macroecological patterns
By bringing together more than 100 contributors, we were able to fill a void in our collective understanding of microbial life across all major US watersheds.
communities.springernature.com
December 6, 2024 at 8:29 PM
blueskyroast.com breaks down my @bsky.app persona.

I feel talked up, not roasted 😂🤩

Content Analysis: Their posts read like a cool nerd’s invitation to a party—informative, engaging, and sprinkled with a dash of enthusiasm. Just don't expect any wild emojis; they save those for the lab!
December 4, 2024 at 3:39 AM
Reposted by Scott Wrigley
Join us at the CoSMic/GRAM social this Friday, December 6th! This is a fantastic opportunity to connect with fellow microbiome enthusiasts, share ideas, and strengthen our vibrant community.

📅 Friday, December 6th, 2024
⏰ 4:00 – 6:00 PM
📍 Gilded Goat Brewing Company - Downtown Ft Collins
December 2, 2024 at 4:23 PM
Reposted by Scott Wrigley
Thrilled to announce that Matthias Hülsmann's new perspective is now out in @naturemicrobiol.bsky.social! This exciting work is shaping how our group thinks about collective microbiome metabolism. Check it out! www.nature.com/articles/s41...
A framework for understanding collective microbiome metabolism - Nature Microbiology
This Perspective explores why microbiome members perform partial metabolism of substrates and suggests that proteome efficiency is a driver of collective microbiome metabolism.
www.nature.com
November 26, 2024 at 12:45 PM
Reposted by Scott Wrigley
More exciting research from CSU Microbiome Network was recently published in PLOS ONE! The study highlights the fascinating intersection of microbiome science and public perceptions.

Check out the paper in PLOSOne here: journals.plos.org/plosone/arti...
Examination of public perceptions of microbes and microbiomes in the United States reveals insights for science communication
Within a changing research and media landscape, misconceptions and misinformation about microorganisms and microbiomes can arise, necessitating improvements in science communication practices through ...
journals.plos.org
November 26, 2024 at 4:23 PM
Reposted by Scott Wrigley
Great article detailing the work of Colorado State Microbiome (CoSMic) Network Research Professor Mikayla Borton, #CoSMic Co-Director Kelly Wrighton, and collaborators.

In addition to the article below, check out the publication here in Nature:

www.nature.com/articles/s41...

#GRAM #Microbiome
November 25, 2024 at 5:45 PM
Some highlights from my poster presentation titled "Treating Severe Acute Malnutrition: The Impact of Gut Microbiome Modulation" at the Colorado State University Graduate Student Showcase. #MicrobiomeScience #GRAM #CoSMic #ColoradoStateUniversity #ScienceCommunication
November 23, 2024 at 6:07 PM
Reposted by Scott Wrigley
1/5
📣 Introducing GRAM: CSU's Microbiome Community on BlueSky! 🧫

Hello, #science community! We’re thrilled to bring #GRAM (Group of Researchers Across Microbiomes) to BlueSky Social.
November 21, 2024 at 4:46 PM