DFG-funded HyperMet Research Unit (FOR 5795)
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hypermet.bsky.social
DFG-funded HyperMet Research Unit (FOR 5795)
@hypermet.bsky.social
The aim of the HyperMet research unit is to investigate the metabolic health effects of skeletal muscle hypertrophy and atrophy using advanced methods of metabolic research. Speakers Henning Wackerhage & Hanna Taipaleenmäki
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📌 This is (many of) us! 💪🏽

From left to right: Eckhard Wolf, Karsten Hiller, Franz Schilling , Rainer Okrojek, Arne Hinrichs, Martin Hrabe de Angelis, Ken Dyar, Manfred Blobner and Dominik Lutter.

Front: Nathalia Dragano, Hanna Taipaleenmäki, Henning Wackerhage, Maria Rohm and Gabi Kastenmüller.
Important article linking methylation clocks to frailty: Biological age measured by DNA methylation clocks and frailty: a systematic review and meta-analysis - The Lancet Healthy Longevity www.thelancet.com/journals/lan...
Biological age measured by DNA methylation clocks and frailty: a systematic review and meta-analysis
Higher GrimAge EAA is consistently associated with higher frailty. Future research should focus on developing and validating DNA methylation clocks that integrate molecular surrogates of health risk a...
www.thelancet.com
November 10, 2025 at 7:56 AM
Troy Hornberger leads research into how hypertrophying muscle generates additional biomass. He is giving the 18th HyperMet talk on the 4th of December from 15-16 h Munich time. The Zoom link is: tum-conf.zoom-x.de/j/6756494866...
Password: 929686
November 6, 2025 at 8:38 AM
Great to see so many HyperMet members and exercise physiologists with metabolomics data at the DGMet meeting in Hannover. This is a growing field and it is important for us to learn to not only generate data mountains but new ideas that are useful for practice!
October 2, 2025 at 7:44 AM
Cholsoon Jang is coming as a visiting Professor to Munich for some experimental masterclasses and will give the 19th HyperMet talk next Thursday in person. Join us (details below)!
September 19, 2025 at 7:33 AM
Pumping Iron Is Their Secret to Aging Well. Not only important for independence & mobility but muscle hypertrophy also has anti-obesity and anti-diabetes effects! www.nytimes.com/2025/07/26/w...
Pumping Iron Is Their Secret to Aging Well
www.nytimes.com
September 12, 2025 at 5:56 PM
TUM is offering a global postdoc fellowship for talented researchers with a local host. Please e-mail me if you have any questions! Info here: www.tum.de/en/about-tum...
TUM Global Postdoc Fellowship - TUM
www.tum.de
September 12, 2025 at 4:51 PM
Congratulations to the authors for publishing this paper in on the metabolism of muscle atrophy in Cell Reports! It shows that atrophy is more than just amino acids being released into the circulation.
www.cell.com/cell-reports...
Multi-dimensional metabolomic remodeling under diverse muscle atrophic stimuli in vivo
Oyabu et al. establish a metabolomics dataset of muscle-atrophy-associated metabolites (“atrometabolites”) and identify impaired polyamine synthesis as a common feature of various muscle atrophy. The ...
www.cell.com
September 11, 2025 at 7:10 AM
Erik Richter is an exercise physiology legend and will give the 18th HyperMet talk on interaction of exercise and insulin on glucose uptake. tomorrow, Thursday, 28.08.2025 15-16 h Munich time. The Zoom-link is here:
tum-conf.zoom-x.de/j/6920502369...
Password: 702487
August 27, 2025 at 11:05 AM
One major, unsolved problem is all those unknown signals in MS metabolomics data. To predict what they are, Mike Skinneder has developed DeeMet. He will give the 17th HyperMet talk next Thursday at 15 h Munich time. Join here (please RT): tum-conf.zoom-x.de/j/6392132327...
August 16, 2025 at 7:39 AM
Really looking forward to Lykke Sylow given the 16th HyperMet talk this Thursday 15 h. Whe will talk about the effect of hypertrophy stimulation on fat mass and glucose homeostasis (recent preprint). Please RT and join here: tum-conf.zoom-x.de/j/6903199711...
August 11, 2025 at 8:13 AM
Monday the 28.07. is the deadline for submitting posters for the meeting in Hanover on the 1.-2. of October 2025. Join if you are interested in metabolomics, the vLamax or other exercise & muscle metabolism topics! Many HyperMet researchers will attend! dgmet.de/event/save-t...
July 26, 2025 at 6:15 PM
Party time! Meet the A team who has just finished a 6 week 3x weekly hard ExBat2 training study as part of @batenergy.bsky.social
May 26, 2025 at 12:34 PM
Right after the fantastic talk by David Glass we have Jonathan Z. Long giving a talk on Thursday, 22. May 2025 17-18 h Munich time. Jonathans' team has identified exercise and diet-regulated metabolites such as lac-phe that control appetite. Listen in!
tum-conf.zoom-x.de/j/6697271114...
May 18, 2025 at 6:01 PM
Absolutely deligthed that David Glass will give the 11th HyperMet talk this Thursday. His title is: "Aging effects of genes effecting skeletal muscle atrophy and hypertrophy" Join on the 15.5. from 15-16 h Munich time
tum-conf.zoom-x.de/j/6395626690...
Password: 045026 Please RT
May 12, 2025 at 8:31 PM
*HyperMet has potential, also financially*
Current talk "Intellectual property” & your science” from Ms. Elke Achhammer (TUM ForTe) on April 3, 2025
web.tum.de/en/hypermet/...
April 28, 2025 at 11:30 AM
We are shocked and very sad to hear that Joern Rittweger has suddenly passed away. He was one of the few researchers in Germany that did human muscle biopsy studies www.dlr.de/en/me/latest...
DLR Institute of Aerospace Medicine mourns the loss of Prof. Dr Jörn Rittweger
It is with great dismay and deep sadness that we bid farewell to Prof. Dr Jörn Rittweger, who passed away suddenly and unexpectedly on 21 April 2025 at the age of 63.
www.dlr.de
April 25, 2025 at 7:53 AM
Join us on the 1-2. of October 2025 in Hannover at the meeting of the German society for metabolome research (DGMet) to present about exercise & muscle metabolism. The exercise & muscle metabolims session will be in English. International delegates welcome! Please RT.
March 24, 2025 at 8:25 AM
Listening to Avery Faigenbaum, a scientific leader on resistance training in children and adolescents at the NSCA conference at @tum.de
March 15, 2025 at 11:10 AM
Looking forward to presenting the @dfg.de funded @hypermet.bsky.social story to the people at the NSCA conference at @tum.de
March 15, 2025 at 7:57 AM
Looking forward to presenting the ideas of the @dfg.de funded HyperMet research unit at the PMU winter school in bonny Salzburg!
February 27, 2025 at 6:37 AM
We are launching a DGMet exercise & muscle metabolism working group. The aim of the group is to research exercise and muscle metabolism, using especially advanced methods of metabolic research such as metabolomics. Interested in joining? Register here: dgmet.de
February 23, 2025 at 3:44 PM
Coming Thursday (27.02.) @cholsoon_jang will give the 9th HyperMet Zoom-talk from 16-17 h Munich time on inter-organ metabolic crosstalk revealed by av metabolomics.
tum-conf.zoom-x.de/j/6187093561...
Password: 57728
February 23, 2025 at 9:22 AM
Reposted by DFG-funded HyperMet Research Unit (FOR 5795)
Viele wissen das: Um eine DFG-Förderung zu erhalten, müssen sich #Hochschulen und andere #Forschungseinrichtungen zur "guten wissenschaftlichen Praxis" verpflichten.
Die Leitlinien des #GWP-Kodex erläutern hier die Prinzipien und geben Hilfestellung: wissenschaftliche-integritaet.de/kodex/verpfl...
Verpflichtung auf die allgemeinen Prinzipien - Wissenschaftliche Integrität
Hochschulen und außerhochschulische Forschungseinrichtungen legen unter Beteiligung ihrer wissenschaftlichen Mitglieder die Regeln für gute wissenschaftliche Praxis fest, geben sie ihren Angehörigen b...
wissenschaftliche-integritaet.de
February 19, 2025 at 1:29 PM
Reposted by DFG-funded HyperMet Research Unit (FOR 5795)
RESEARCH | S Loopmans, @geertlab.bsky.social et al. (KU Leuven):

The pentose phosphate pathway in #chondrocytes provides reducing power to ensure proteostasis necessary for #bone lengthening 🦴 🐁

https://bit.ly/3X1RuDS
The pentose phosphate pathway controls oxidative protein folding and prevents ferroptosis in chondrocytes - Nature Metabolism
Loopmans et al. show that the pentose phosphate pathway in chondrocytes provides reducing power to ensure proteostasis necessary for bone lengthening.
bit.ly
February 16, 2025 at 7:16 PM
Just a reminder for all the Munich people that Karsten Köhler is organising this event on Wednesday for free!
February 17, 2025 at 9:26 AM