Hubrecht Institute
@hubrechtinstitute.bsky.social
Contributing to a better world through research into the fundamental processes of living cells, tissues and organisms. The Hubrecht Institute is a research institute of KNAW and is affiliated with the UMC Utrecht.
Find the full article (open access) at www.nature.com/articles/s41...
October 30, 2025 at 1:12 PM
Find the full article (open access) at www.nature.com/articles/s41...
New publication in @natbiotech.nature.com! Wim de Lau and colleagues from @hansclevers.bsky.social group describe an integrin-activating antibody that enhances organoid growth also in, medical-grade, collagen. An important step toward more affordable and translational organoid culture systems.
October 30, 2025 at 1:12 PM
New publication in @natbiotech.nature.com! Wim de Lau and colleagues from @hansclevers.bsky.social group describe an integrin-activating antibody that enhances organoid growth also in, medical-grade, collagen. An important step toward more affordable and translational organoid culture systems.
Can blood vessel organoids help us generate transplantable blood stem cells in the lab? Fabien Boudia can now explore this question thanks to a Marie Skłodowska-Curie Actions Postdoctoral Fellowship. Read more about his project via www.hubrecht.eu/marie-curie-...
October 23, 2025 at 12:19 PM
Can blood vessel organoids help us generate transplantable blood stem cells in the lab? Fabien Boudia can now explore this question thanks to a Marie Skłodowska-Curie Actions Postdoctoral Fellowship. Read more about his project via www.hubrecht.eu/marie-curie-...
Researchers at Hubrecht Institute and Radboud University developed an animal-free gel in which organoids can grow and expand long-term. The PIC-invasin gel allows for more consistent, ethical and affordable organoid research. @hansclevers.bsky.social @pnas.org
🔗 https://f.mtr.cool/cekttmhhtn
🔗 https://f.mtr.cool/cekttmhhtn
October 21, 2025 at 3:08 PM
Researchers at Hubrecht Institute and Radboud University developed an animal-free gel in which organoids can grow and expand long-term. The PIC-invasin gel allows for more consistent, ethical and affordable organoid research. @hansclevers.bsky.social @pnas.org
🔗 https://f.mtr.cool/cekttmhhtn
🔗 https://f.mtr.cool/cekttmhhtn
What is this? It is cohesin, a molecular machine inside our cells, looping the DNA. Today, researchers at the Hubrecht Institute and NKI published a new molecular tool that allows them to study the effects of this process in living cells: www.nature.com/articles/s41....
🎥 Cees Dekker Lab, TU Delft.
🎥 Cees Dekker Lab, TU Delft.
October 16, 2025 at 9:11 AM
What is this? It is cohesin, a molecular machine inside our cells, looping the DNA. Today, researchers at the Hubrecht Institute and NKI published a new molecular tool that allows them to study the effects of this process in living cells: www.nature.com/articles/s41....
🎥 Cees Dekker Lab, TU Delft.
🎥 Cees Dekker Lab, TU Delft.
Save the date! The second Hubrecht Symposium will take place on March 26, 2026. This year’s theme is “Molecular Machines in Development”, with Petra Hajkova, Andrea Pauli and @danielgerlich.bsky.social as keynote speakers. Registration opens soon, stay tuned via hubrecht.eu/hubrecht-symposium/.
October 7, 2025 at 11:10 AM
Save the date! The second Hubrecht Symposium will take place on March 26, 2026. This year’s theme is “Molecular Machines in Development”, with Petra Hajkova, Andrea Pauli and @danielgerlich.bsky.social as keynote speakers. Registration opens soon, stay tuned via hubrecht.eu/hubrecht-symposium/.
Congratulations to @hansclevers.bsky.social for receiving the Spanish Abarca Prize. "By discovering the Lgr5 marker and introducing gut organoid culture, he laid the foundation for a technology that today redefines biomedical research and clinical care." www.abarcaprize.com
October 2, 2025 at 1:23 PM
Congratulations to @hansclevers.bsky.social for receiving the Spanish Abarca Prize. "By discovering the Lgr5 marker and introducing gut organoid culture, he laid the foundation for a technology that today redefines biomedical research and clinical care." www.abarcaprize.com
We spoke to Miguel Leung, who today celebrates his first year as a group leader at the Hubrecht Institute. His group uses structural cell biology to study reproduction and microbial diversity at atomic resolution. Read the full interview here: www.hubrecht.eu/one-year-in-...
October 1, 2025 at 9:47 AM
We spoke to Miguel Leung, who today celebrates his first year as a group leader at the Hubrecht Institute. His group uses structural cell biology to study reproduction and microbial diversity at atomic resolution. Read the full interview here: www.hubrecht.eu/one-year-in-...
Congrats to @maxmadern.bsky.social from the @marvintanenbaum.bsky.social group! He received the CS&D Best Publication Award for work revealing that ribosomes can help each other when translating tricky sequences. This was made possible by a method using circular RNA to watch ribosomes in action.
September 30, 2025 at 10:17 AM
Congrats to @maxmadern.bsky.social from the @marvintanenbaum.bsky.social group! He received the CS&D Best Publication Award for work revealing that ribosomes can help each other when translating tricky sequences. This was made possible by a method using circular RNA to watch ribosomes in action.
Looking for a Sunday activity, suitable for curious minds (young and old)? Visit our stand at Utrecht University on October 5th, during the Weekend of Science!
Here, you can discover all about DNA and learn more about the research at the Hubrecht Institute. More details below! 👇
Here, you can discover all about DNA and learn more about the research at the Hubrecht Institute. More details below! 👇
September 29, 2025 at 9:35 AM
Looking for a Sunday activity, suitable for curious minds (young and old)? Visit our stand at Utrecht University on October 5th, during the Weekend of Science!
Here, you can discover all about DNA and learn more about the research at the Hubrecht Institute. More details below! 👇
Here, you can discover all about DNA and learn more about the research at the Hubrecht Institute. More details below! 👇
Utrecht Science Week opened today! From September 26th to October 5th, Utrecht Science Park opens its doors to the public. Curious to see our labs from the inside? Register for our tour on October 2nd: https://www.utrechtsciencepark.nl/en/utrecht-science-week/programme?open=184. More details below 👇
September 26, 2025 at 7:45 PM
Utrecht Science Week opened today! From September 26th to October 5th, Utrecht Science Park opens its doors to the public. Curious to see our labs from the inside? Register for our tour on October 2nd: https://www.utrechtsciencepark.nl/en/utrecht-science-week/programme?open=184. More details below 👇
Ready to establish your own research group at the Hubrecht Institute for Molecular and Developmental Biology? We’re seeking a tenure-track group leader to develop an innovative research line within our vibrant scientific community. Learn more & apply! https://f.mtr.cool/jncxfqkuds
September 26, 2025 at 1:53 PM
Ready to establish your own research group at the Hubrecht Institute for Molecular and Developmental Biology? We’re seeking a tenure-track group leader to develop an innovative research line within our vibrant scientific community. Learn more & apply! https://f.mtr.cool/jncxfqkuds
🧬 Hubrecht researchers have developed a method that can detect DNA methylation and histone modifications simultaneously in single cells. They can now for the first time study how their interaction influences gene activity. https://www.nature.com/articles/s41592-025-02847-4
@jervdberg.bsky.social
@jervdberg.bsky.social
September 25, 2025 at 9:04 AM
🧬 Hubrecht researchers have developed a method that can detect DNA methylation and histone modifications simultaneously in single cells. They can now for the first time study how their interaction influences gene activity. https://www.nature.com/articles/s41592-025-02847-4
@jervdberg.bsky.social
@jervdberg.bsky.social
Congratulations to Juan Garaycoechea, @puckknipscheer.bsky.social and team CAUSE for being shortlisted in this year’s @cancergrand.bsky.social! They compete with 11 teams for £20M to study how DNA damage leads to mutation signatures in our DNA that can cause cancer. #CancerGrandChallenges
September 24, 2025 at 1:18 PM
Congratulations to Juan Garaycoechea, @puckknipscheer.bsky.social and team CAUSE for being shortlisted in this year’s @cancergrand.bsky.social! They compete with 11 teams for £20M to study how DNA damage leads to mutation signatures in our DNA that can cause cancer. #CancerGrandChallenges
Kim de Luca, Hubrecht alumna from the Kind group, was featured by MIT Technology Review in this year's Innovators Under 35! Swipe to read more.
The full list can be found here: http://www.technologyreview.com/innovators-under-35/2025/.
The full list can be found here: http://www.technologyreview.com/innovators-under-35/2025/.
September 11, 2025 at 8:36 AM
Kim de Luca, Hubrecht alumna from the Kind group, was featured by MIT Technology Review in this year's Innovators Under 35! Swipe to read more.
The full list can be found here: http://www.technologyreview.com/innovators-under-35/2025/.
The full list can be found here: http://www.technologyreview.com/innovators-under-35/2025/.
Intestinal cells are replaced every few days. Scientists always assumed that excess cells were pushed out to remove them, but now show that cells instead pull at each other in a sort of tug-of-war game to remove the weakest ones. 👉 www.hubrecht.eu/intestinal-cells-pull
@hansclevers.bsky.social
@hansclevers.bsky.social
September 4, 2025 at 6:05 PM
Intestinal cells are replaced every few days. Scientists always assumed that excess cells were pushed out to remove them, but now show that cells instead pull at each other in a sort of tug-of-war game to remove the weakest ones. 👉 www.hubrecht.eu/intestinal-cells-pull
@hansclevers.bsky.social
@hansclevers.bsky.social
Congratulations to the Bothma group for becoming the very first lab at our institute to achieve a LEAF Silver certificate!
We are proud to see our labs adopting more sustainable practices, and we will continue working to make the Hubrecht Institute future-proof!
We are proud to see our labs adopting more sustainable practices, and we will continue working to make the Hubrecht Institute future-proof!
August 29, 2025 at 11:56 AM
Congratulations to the Bothma group for becoming the very first lab at our institute to achieve a LEAF Silver certificate!
We are proud to see our labs adopting more sustainable practices, and we will continue working to make the Hubrecht Institute future-proof!
We are proud to see our labs adopting more sustainable practices, and we will continue working to make the Hubrecht Institute future-proof!
Just one month left to apply for the Hubrecht International PhD Program! This fully funded 4-year PhD offers the opportunity to join a high-profile lab in molecular & developmental biology, exceptional training, and mentorship from leading scientists.
Apply before September 15 www.hubrecht.eu/hipp/
Apply before September 15 www.hubrecht.eu/hipp/
August 14, 2025 at 10:02 AM
Just one month left to apply for the Hubrecht International PhD Program! This fully funded 4-year PhD offers the opportunity to join a high-profile lab in molecular & developmental biology, exceptional training, and mentorship from leading scientists.
Apply before September 15 www.hubrecht.eu/hipp/
Apply before September 15 www.hubrecht.eu/hipp/
We are deeply saddened by the passing of our colleague Catherine Rabouille.
Catherine was senior group leader at the Hubrecht Institute, an exceptional cell biologist, a passionate mentor, and a driving force for diversity and inclusion in science.
Full tribute: www.hubrecht.eu/in-memoriam-...
Catherine was senior group leader at the Hubrecht Institute, an exceptional cell biologist, a passionate mentor, and a driving force for diversity and inclusion in science.
Full tribute: www.hubrecht.eu/in-memoriam-...
August 11, 2025 at 1:21 PM
We are deeply saddened by the passing of our colleague Catherine Rabouille.
Catherine was senior group leader at the Hubrecht Institute, an exceptional cell biologist, a passionate mentor, and a driving force for diversity and inclusion in science.
Full tribute: www.hubrecht.eu/in-memoriam-...
Catherine was senior group leader at the Hubrecht Institute, an exceptional cell biologist, a passionate mentor, and a driving force for diversity and inclusion in science.
Full tribute: www.hubrecht.eu/in-memoriam-...
🧬 Looking for a PhD position in molecular or developmental biology? 🔬
✉️ The Hubrecht Institute now has its very own PhD program! Applications are open and will be accepted until September 15th. Read more here 👉 www.hubrecht.eu/hipp/
✉️ The Hubrecht Institute now has its very own PhD program! Applications are open and will be accepted until September 15th. Read more here 👉 www.hubrecht.eu/hipp/
July 10, 2025 at 11:19 AM
🧬 Looking for a PhD position in molecular or developmental biology? 🔬
✉️ The Hubrecht Institute now has its very own PhD program! Applications are open and will be accepted until September 15th. Read more here 👉 www.hubrecht.eu/hipp/
✉️ The Hubrecht Institute now has its very own PhD program! Applications are open and will be accepted until September 15th. Read more here 👉 www.hubrecht.eu/hipp/
🧬 How do epigenetic modifications change over time in the same cell? Are they maintained during cell divisions?
Researchers from the Kind and Van Oudenaarden groups have found a way to study these types of questions: www.nature.com/articles/s41.... Read more below! 👇
@jopkind.bsky.social
Researchers from the Kind and Van Oudenaarden groups have found a way to study these types of questions: www.nature.com/articles/s41.... Read more below! 👇
@jopkind.bsky.social
July 10, 2025 at 9:10 AM
🧬 How do epigenetic modifications change over time in the same cell? Are they maintained during cell divisions?
Researchers from the Kind and Van Oudenaarden groups have found a way to study these types of questions: www.nature.com/articles/s41.... Read more below! 👇
@jopkind.bsky.social
Researchers from the Kind and Van Oudenaarden groups have found a way to study these types of questions: www.nature.com/articles/s41.... Read more below! 👇
@jopkind.bsky.social
🧬What makes one cell different from another? Kim de Luca developed methods that help answer this question. They can be used to study DNA organization, regulation and repair in single cells. Today she successfully defended her thesis. Congratulations Kim!🎓 Read more 👉 www.hubrecht.eu/phd-kim-de-l...
June 30, 2025 at 2:46 PM
🧬What makes one cell different from another? Kim de Luca developed methods that help answer this question. They can be used to study DNA organization, regulation and repair in single cells. Today she successfully defended her thesis. Congratulations Kim!🎓 Read more 👉 www.hubrecht.eu/phd-kim-de-l...
The Den Hertog group uncovered a surprising mechanism in zebrafish tail development: when cells from Kupffer’s vesicle fail to migrate, a second tail-like structure can form. The discovery emerged during a screen of fungal metabolites. www.hubrecht.eu/tail-develop... @dev-journal.bsky.social
June 24, 2025 at 9:05 AM
The Den Hertog group uncovered a surprising mechanism in zebrafish tail development: when cells from Kupffer’s vesicle fail to migrate, a second tail-like structure can form. The discovery emerged during a screen of fungal metabolites. www.hubrecht.eu/tail-develop... @dev-journal.bsky.social
On 🌎World Sickle Cell Day🩸 we share a new gene therapy approach that holds promise for patients with sickle cell disease, thalassemia and possibly other genetic diseases.🧬 Researchers from the Hubrecht Institute, Erasmus MC, Sanquin and Oncode found a new method to switch genes on.
June 19, 2025 at 12:34 PM
On 🌎World Sickle Cell Day🩸 we share a new gene therapy approach that holds promise for patients with sickle cell disease, thalassemia and possibly other genetic diseases.🧬 Researchers from the Hubrecht Institute, Erasmus MC, Sanquin and Oncode found a new method to switch genes on.
Organoid group researchers created mini airway submucosal glands, or organoids, that produce region-specific mucus and function just like real glands in our lungs. A powerful tool to study how our airways repair themselves, react to inflammation, and fight off viruses.
@cp-cellstemcell.bsky.social
@cp-cellstemcell.bsky.social
June 13, 2025 at 1:03 PM
Organoid group researchers created mini airway submucosal glands, or organoids, that produce region-specific mucus and function just like real glands in our lungs. A powerful tool to study how our airways repair themselves, react to inflammation, and fight off viruses.
@cp-cellstemcell.bsky.social
@cp-cellstemcell.bsky.social