Hannah Stuart
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htstuart.bsky.social
Hannah Stuart
@htstuart.bsky.social
Incoming Group Leader @embl.org Barcelona
https://www.embl.org/groups/stuart/
Postdoc @jamesbriscoe.bsky.social @crick.ac.uk & tanakalab.org @imbavienna.bsky.social
PhD @josesilvalab.bsky.social @scicambridge.bsky.social
Reposted by Hannah Stuart
(1/8) Very Happy to share our lab’s 3D post-implantation human embryo model, made via signalling reprograming!
🙌 Huge thanks to the entire team and our collaborators, special shout-out to @cc0447.bsky.social (led the work) and @jinjin-0101.bsky.social (comp. analysis).
www.cell.com/cell-stem-ce...
Signaling reprogramming via Stat3 activation unravels high-fidelity human post-implantation embryo modeling
Enhanced STAT3 activation combined with TGF-β inhibition reprograms human PSCs into cells specifying all early embryonic lineages. Upon 3D suspension culture, these cells self-organize within 6 days i...
www.cell.com
September 16, 2025 at 4:12 PM
Reposted by Hannah Stuart
(1/3) A while back, my then-PhD student @htstuart.bsky.social stumbled on a finding that changed our lab’s direction 👀✨. Turns out, STAT3 mediated reprogramming generates intermediates (Gata6GFP+ cells) going through an earlier developmental stage with increased developmental potential 🚀
September 15, 2025 at 1:51 AM
Reposted by Hannah Stuart
📢 Recruitment for the EMBL International PhD Programme is officially open!

At EMBL, we train young scientists to become skilled and creative future leaders in academia and other sectors. Join us and get a head start on your career in life sciences!

bit.ly/47mmiFF
September 1, 2025 at 9:07 AM
Reposted by Hannah Stuart
A perfect start in the new year! 🌱 Regenerating tissues are just an amazing spatio temporal controlled process! Our new manuscript explores how cell heterogeneity and bistability orchestrate intestinal regeneration. 🧵 biorxiv.org/cgi/content/...
Cell heterogeneity and fate bistability drive tissue patterning during intestinal regeneration
Tissue regeneration relies on the ability of cells to undergo de novo patterning. While tissue patterning has been viewed as the transition from initially identical un-patterned cells to an arrangemen...
biorxiv.org
January 15, 2025 at 5:32 PM
Reposted by Hannah Stuart
🌛Western sessions: Our classic VGZT seminars will continue bi-weekly on Thursdays, featuring the same time and format as before. Check out the speaker lineup and in the future, look for the 🌙 symbol in the flyers for individual sessions. [2/4]
December 30, 2024 at 10:48 AM
Reposted by Hannah Stuart
📢Vote for the 2024 Development cover image of the year

@dev-journal.bsky.social featured 24 cover images in 2024. Now is the chance to pick your favourite!

Browse through the images and vote by 13 Jan:
https://thenode.biologists.com/vote-for-the-2024-development-cover-image-of-the-year/

#DevBio
December 27, 2024 at 1:56 PM