PAE looks like this. The iPTM score is also 0.74, so these helices are really unreliable, and they take up a considerable amount of amino acids in the total sequence.

AF3 predictions for a 500 kDa protein without (left) and with (right) a known 40 kDa binding partner. Apparently disordered regions collapsing into low confidence cytosolic helices. Is AF hallucinating these helices?

pain, just literal pain