Our data collectively support a model according to which VPS13C acts upstream of OSBP/ORP lipid transport proteins to orchestrate bulk lipid transport in synchrony with lysosomal damage and repair, thereby maintaining lysosome integrity

As ER-lysosome contact sites bridged by VPS13C have a gap width that cannot be resolved by light microscopy, we used a ratiometric approach to simultaneously trace fluorescence levels of ER-derived lipids & ER membrane proteins on the surface of damaged lysosomes containing pHrodo-labeled microbeads

🚨🚨🚨 We are launching the 2nd application round for the Erasmus Mundus Joint Master’s Program MemBioMed, offering cutting-edge training on exploring the complex behavior of cellular membranes & unlocking their therapeutic potential. Students can apply here: life.univ-cotedazur.eu/internationa...

I am proud to 📣 today’s superb thesis defense by Milena Wessing on “Molecular dissection of ceramide-induced apoptosis: a bottom-up approach”. Two papers describing Milena’s heroic efforts are close to submission. It was a privilege serving as her “Doktorvater” 🥂

I am pleased to 📣 today’s superb thesis defense by Christian Schroer on “Chemical strategies for studying lipid signaling and transport”. Part of his work was recently published in the JLR; the other part will follow soon. A very proud and somewhat tipsy “Doktorvater” 🥂

🚨🚨 We are proud to launch MemBioMed, a new international Master program offering interdisciplinary training in biomembrane research at 3 sites: Université de Côte d'Azur 🇫🇷 Università di Genova 🇮🇹 & Osnabrück University 🇩🇪. We offer 15 scholarships & encourage talented students to apply by April 6th ♻️🙏

"Democracy needs Science. Science needs Democracy". Germany is facing a landmark federal election. I am proud to be part of a university whose presidential board takes a clear stance that argues from the self-image of science. Please share👇

MD simulations and experiments in cells reveal core structural determinants that govern binding of Hexokinase I to mitochondrial VDACs, a liaison with far-reaching physiological implications. Another great collaborative effort with @melolab.bsky.social and @cg-martini.bsky.social! rdcu.be/d9lO8

🚨🚨 We are proud to launch MemBioMed, a new international Master program offering interdisciplinary training in biomembrane research at 3 sites: Université de Côte d'Azur 🇫🇷 Università di Genova 🇮🇹 & Osnabrück University 🇩🇪. We offer 15 scholarships & encourage talented students to apply by April 6th ♻️🙏

📯📯Do not miss the Sphingolipid Biology Young Researcher Contest on Tue 14th January! Free registration at sphingolipidbiology.com/registrations. Please repost!📯📯