Alexandre Hofer
@hofalex.bsky.social
R&D bioorganic chemist in biotech.
High affinity to nucleotides and nucleic acids.
All views my own.
High affinity to nucleotides and nucleic acids.
All views my own.
Imagine a small molecule that degrades a target protein like PROTACs, but does so independently of any of the host cell's degradation machinery, so you can go and do targeted protein degradation in gram-negative bacteria: doi.org/10.26434/che...
July 24, 2025 at 5:33 AM
Imagine a small molecule that degrades a target protein like PROTACs, but does so independently of any of the host cell's degradation machinery, so you can go and do targeted protein degradation in gram-negative bacteria: doi.org/10.26434/che...
Great transition into the new year with a well-organised party...
January 1, 2025 at 3:53 PM
Great transition into the new year with a well-organised party...
A white Christmas for once...
December 26, 2024 at 10:54 PM
A white Christmas for once...
Little copycats in the house...
December 23, 2024 at 8:40 AM
Little copycats in the house...
Do not confuse...
November 16, 2024 at 9:36 PM
Do not confuse...
Thanks @cambridgeindy.bsky.social for publishing my view on closing the Mill Road Bridge for private vehicles.
October 3, 2024 at 10:51 AM
Thanks @cambridgeindy.bsky.social for publishing my view on closing the Mill Road Bridge for private vehicles.
Quite faint in the middle of town, but one could clearly see the northern lights in Cambridge, UK.
May 11, 2024 at 8:58 AM
Quite faint in the middle of town, but one could clearly see the northern lights in Cambridge, UK.
When you only have scientific magazines at hand for some arts and crafts with your daughter...
December 18, 2023 at 11:51 AM
When you only have scientific magazines at hand for some arts and crafts with your daughter...