Houming Chen
@hmchen93.bsky.social
plant cell biologist / postdoc @ unige
Happy to share our latest manuscript about Brassinosteroid recognition 😎 hope it offers a broad and intensive understanding of BR ligands--BRI1-LIKE receptors mechanism.
A mechanistic framework for the recognition of chemically diverse brassinosteroids by BRI1-family receptor kinases https://www.biorxiv.org/content/10.1101/2025.08.08.669299v1
August 9, 2025 at 10:00 PM
Happy to share our latest manuscript about Brassinosteroid recognition 😎 hope it offers a broad and intensive understanding of BR ligands--BRI1-LIKE receptors mechanism.
Reposted by Houming Chen
Our latest on brassinosteroid signaling: Ligand binding spectrum, specificity & selectivity of all BR receptors in Arabidopsis. By @albertocaregnato.bsky.social , @hmchen93.bsky.social and our great chemistry collaborators Mirek Kvasnica, Jana Oklestkova and Mirek Strnad.
August 9, 2025 at 9:01 PM
Our latest on brassinosteroid signaling: Ligand binding spectrum, specificity & selectivity of all BR receptors in Arabidopsis. By @albertocaregnato.bsky.social , @hmchen93.bsky.social and our great chemistry collaborators Mirek Kvasnica, Jana Oklestkova and Mirek Strnad.
Reposted by Houming Chen
Nice analysis of ITPK and VIH inositol pyrophophate kinase over-expression lines in Arabidopsis. onlinelibrary.wiley.com/doi/10.1111/...
Enhancing inositol pyrophosphate accumulation in plants alters growth, phosphate homeostasis, and insect herbivory
This research investigates the physiological and biochemical impacts of increasing inositol pyrophosphates, molecules involved in plant phosphate sensing and jasmonic acid signaling, in Arabidopsis. ...
onlinelibrary.wiley.com
July 11, 2025 at 9:54 AM
Nice analysis of ITPK and VIH inositol pyrophophate kinase over-expression lines in Arabidopsis. onlinelibrary.wiley.com/doi/10.1111/...
Reposted by Houming Chen
Shedding light on the structure-function mechanisms of LRR-RPs. Our research merges #AlphaFold3, years of literature and functional validation to reveal diverse ligand-binding mechanisms and a conserved co-receptor association mechanism. www.biorxiv.org/content/10.1...
July 9, 2025 at 11:45 AM
Shedding light on the structure-function mechanisms of LRR-RPs. Our research merges #AlphaFold3, years of literature and functional validation to reveal diverse ligand-binding mechanisms and a conserved co-receptor association mechanism. www.biorxiv.org/content/10.1...
Reposted by Houming Chen
New Online! Mechanisms of auxin action in plant growth and development
Mechanisms of auxin action in plant growth and development
Nature Reviews Molecular Cell Biology, Published online: 19 May 2025; doi:10.1038/s41580-025-00851-2The phytohormone auxin coordinates plant growth by forming local maxima and gradients through cell-to-cell transport and metabolic control. Recent research has identified novel signalling mechanisms involving extracellular auxin perception and auxin-mediated cyclic AMP production.
bit.ly
May 19, 2025 at 1:54 PM
New Online! Mechanisms of auxin action in plant growth and development
novel and in-depth work 👍🏻
Delighted to share one piece of my postdoc work in preprint: Through forward genetic screening for suberin deposition in root endodermis, we identified SUBER GENE 1 (SBG1) by GWAS as a novel regulator for suberization by interacting with Type One Protein Phosphatase. www.biorxiv.org/content/10.1...
May 13, 2025 at 6:10 PM
novel and in-depth work 👍🏻
Reposted by Houming Chen
New Article: "Structural mechanism underlying PHO1;H1-mediated phosphate transport in Arabidopsis" rdcu.be/d62pA
Phosphate transporter PHO1: cryo-EM, biochemical & physiological analysis. Molecular and regulatory mechanism of transport mediated by the SPX–EXS family. #PlantScience
Phosphate transporter PHO1: cryo-EM, biochemical & physiological analysis. Molecular and regulatory mechanism of transport mediated by the SPX–EXS family. #PlantScience
January 21, 2025 at 2:50 PM
New Article: "Structural mechanism underlying PHO1;H1-mediated phosphate transport in Arabidopsis" rdcu.be/d62pA
Phosphate transporter PHO1: cryo-EM, biochemical & physiological analysis. Molecular and regulatory mechanism of transport mediated by the SPX–EXS family. #PlantScience
Phosphate transporter PHO1: cryo-EM, biochemical & physiological analysis. Molecular and regulatory mechanism of transport mediated by the SPX–EXS family. #PlantScience
Reposted by Houming Chen
BPMs regulate Arabidopsis seedling development by promoting auxin-independent degradation of the Aux/IAA protein IAA10 https://www.biorxiv.org/content/10.1101/2024.11.26.625463v1
BPMs regulate Arabidopsis seedling development by promoting auxin-independent degradation of the Aux/IAA protein IAA10 https://www.biorxiv.org/content/10.1101/2024.11.26.625463v1
After germination, seedlings undergo etiolated development (skotomorphogenesis), enabling them to gr
www.biorxiv.org
November 28, 2024 at 7:03 PM
BPMs regulate Arabidopsis seedling development by promoting auxin-independent degradation of the Aux/IAA protein IAA10 https://www.biorxiv.org/content/10.1101/2024.11.26.625463v1
Reposted by Houming Chen
Perspectives on a co-option of a familiar signaling pathway for embryo patterning, where phosphorylation of SCREAM by MPK3/6 triggers different outcomes. But..Symmetric Cell Division is EXCITING and essential for generating a mirror-symmetric Guard Cell pair😘🌱.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Yoda screams again - Nature Plants
Nature Plants - Yoda screams again
www.nature.com
December 11, 2024 at 3:54 PM
Perspectives on a co-option of a familiar signaling pathway for embryo patterning, where phosphorylation of SCREAM by MPK3/6 triggers different outcomes. But..Symmetric Cell Division is EXCITING and essential for generating a mirror-symmetric Guard Cell pair😘🌱.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Houming Chen
Super excited to announce that our SCRM story is officially published!!! 🎉🎉🎉
Want to discover the exciting new functions of ICE1/SCRM?
Want to dive into the latest model of plant embryo initiation?
Don’t miss out—check it out here:
nph.onlinelibrary.wiley.com/doi/10.1111/...
Want to discover the exciting new functions of ICE1/SCRM?
Want to dive into the latest model of plant embryo initiation?
Don’t miss out—check it out here:
nph.onlinelibrary.wiley.com/doi/10.1111/...
Phosphorylation‐dependent activation of the bHLH transcription factor ICE1/SCRM promotes polarization of the Arabidopsis zygote
In Arabidopsis thaliana, the asymmetric cell division (ACD) of the zygote gives rise to the embryo proper and an extraembryonic suspensor, respectively. This process is controlled by the ERECTA-YODA...
nph.onlinelibrary.wiley.com
November 17, 2024 at 7:46 PM
Super excited to announce that our SCRM story is officially published!!! 🎉🎉🎉
Want to discover the exciting new functions of ICE1/SCRM?
Want to dive into the latest model of plant embryo initiation?
Don’t miss out—check it out here:
nph.onlinelibrary.wiley.com/doi/10.1111/...
Want to discover the exciting new functions of ICE1/SCRM?
Want to dive into the latest model of plant embryo initiation?
Don’t miss out—check it out here:
nph.onlinelibrary.wiley.com/doi/10.1111/...
Super excited to announce that our SCRM story is officially published!!! 🎉🎉🎉
Want to discover the exciting new functions of ICE1/SCRM?
Want to dive into the latest model of plant embryo initiation?
Don’t miss out—check it out here:
nph.onlinelibrary.wiley.com/doi/10.1111/...
Want to discover the exciting new functions of ICE1/SCRM?
Want to dive into the latest model of plant embryo initiation?
Don’t miss out—check it out here:
nph.onlinelibrary.wiley.com/doi/10.1111/...
Phosphorylation‐dependent activation of the bHLH transcription factor ICE1/SCRM promotes polarization of the Arabidopsis zygote
In Arabidopsis thaliana, the asymmetric cell division (ACD) of the zygote gives rise to the embryo proper and an extraembryonic suspensor, respectively. This process is controlled by the ERECTA-YODA...
nph.onlinelibrary.wiley.com
November 17, 2024 at 7:46 PM
Super excited to announce that our SCRM story is officially published!!! 🎉🎉🎉
Want to discover the exciting new functions of ICE1/SCRM?
Want to dive into the latest model of plant embryo initiation?
Don’t miss out—check it out here:
nph.onlinelibrary.wiley.com/doi/10.1111/...
Want to discover the exciting new functions of ICE1/SCRM?
Want to dive into the latest model of plant embryo initiation?
Don’t miss out—check it out here:
nph.onlinelibrary.wiley.com/doi/10.1111/...