Zeta
hm4nn.bsky.social
Zeta
@hm4nn.bsky.social
A Systems neuroscientist
Dandi, dandiarchive.org, Brainlife brainlife.io/about/ etc are pretty good. But perhaps fostering meaningful interactions between experimentalist and theoretician are ultimate solution.
November 17, 2025 at 2:54 PM
Reposted by Zeta
1. Overshoot 1.5°C unavoidable, but returning below is possible
Every five years without substantial CO2 emission reductions locks in an additional temperature increase of about 0.1°C, and implies an additional need of around 200 billion tonnes CO2 of negative emissions to return to 1.5°C.
Búzios Scientific Statement

100 climate researchers, coordinated by @pik-potsdam.bsky.social & @iiasa.ac.at, released a joint statement to inform the #COP30 negotiations and provide guidance on difficult but doable global efforts designed to limit dangerous overshoot of 1.5°C as much as possible.
Búzios Scientific Statement.pdf
drive.google.com
November 15, 2025 at 9:01 PM
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Quick! My book THE BIG PICTURE: On the Origins of Life, Meaning, and the Universe Itself has a limited-time Kindle deal going on. Get the Ebook for just $1.99 while it lasts. A rousing exploration of the science and philosophy of naturalism for just two bucks!

www.amazon.com/Big-Picture-...
The Big Picture: On the Origins of Life, Meaning, and the Universe Itself
The Big Picture: On the Origins of Life, Meaning, and the Universe Itself - Kindle edition by Carroll, Sean M. . Download it once and read it on your Kindle device, PC, phones or tablets. Use features like bookmarks, note taking and highlighting while reading The Big Picture: On the Origins of Life, Meaning, and the Universe Itself.
www.amazon.com
November 13, 2025 at 8:40 PM
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Bifurcations—an underexplored concept in neuroscience—can help explain how small differences in neural circuits give rise to entirely novel functions, writes Xiao-Jing Wang.

#neuroskyence

www.thetransmitter.org/neural-dynam...
The missing half of the neurodynamical systems theory
Bifurcations—an underexplored concept in neuroscience—can help explain how small differences in neural circuits give rise to entirely novel functions.
www.thetransmitter.org
October 27, 2025 at 1:51 PM
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Rest in peace, Dr. Jane Goodall💚
October 1, 2025 at 6:22 PM
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Time to go shopping! Our neural dynamics hardware schematics and CAD files are available to download on www.allenneuraldynamics.org/tools?catego...

#OpenScienceWeek
September 17, 2025 at 10:26 PM
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For those interested in open neuroscience learning tools, check out the preprint for “RetINaBox: A hands-on tool for experimental neuroscience" that a couple students in my lab worked on in collaboration with the Trenholm lab:

www.biorxiv.org/content/10.1...

🧠📈 🧪
RetINaBox: A hands-on learning tool for experimental neuroscience
An exciting aspect of neuroscience research is developing and testing hypotheses via experimentation. However, due to logistical and financial hurdles, this compelling part of neuroscience research is...
www.biorxiv.org
September 15, 2025 at 3:02 PM
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Want to collaborate with the International Brain Laboratory on your own project? We have funding to work with groups anywhere in the world to do new large-scale projects and we are looking for new partners! Learn more and apply: www.internationalbrainlab.com/ibl-core-apply
September 11, 2025 at 12:27 PM
I would have thought the opposite: it is because the degree of uncertainty/unreliability that pushes things from subconscious to consciousness.
But here's one intuition, which the data supports: if you see something unconsciously, you don't know how well you saw it. In other words, you can't monitor the reliability of your perceptual states without consciousness. This isn't just an 'assumption', there's some evidence for this.
September 1, 2025 at 3:51 AM
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We were asked to write a commentary on NeuroAI for Nat. Rev. Neuro. with Sadra Sadeh, so here it is: www.nature.com/articles/s41...
www.nature.com
August 8, 2025 at 10:31 AM
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1
To predict the behaviour of a primate, would you rather base your guess on a closely related species or one with a similar brain shape? We looked at brains & behaviours of 70 species, you’ll be surprised!

🧵Thread on our new preprint with @r3rt0.bsky.social , doi.org/10.1101/2025...
July 27, 2025 at 5:26 PM
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1/ Mapping synaptic connectivity between individual neurons is extremely laborious. We developed BRISC, a new method that makes it possible to map inputs onto 100s of neurons in the same animal in a matter of weeks! Led by Alex Becalick and @antblot.bsky.social. 🧵

www.biorxiv.org/content/10.1...
Barcoded Rabies In Situ Connectomics for high-throughput reconstruction of neural circuits
Sequencing of oligonucleotide barcodes holds promise as a high-throughput approach for reconstructing synaptic connectivity at scale. Rabies viruses can act as a vehicle for barcode transmission, than...
www.biorxiv.org
July 21, 2025 at 7:58 AM
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In this “Brain Inspired” episode, Paul Middlebrooks and Xiao-Jing Wang discuss how neuroscience has changed over the past 50 years, and how Wang believes modern theoretical tools will lead to a new era of “cross-levels mechanistic understanding.” Listen now: www.thetransmitter.org/brain-inspir...
Xiao-Jing Wang outlines the future of theoretical neuroscience
Wang discusses why he decided the time was right for a new theoretical neuroscience textbook and how bifurcation is a key missing concept in neuroscience explanations.
www.thetransmitter.org
July 2, 2025 at 2:40 PM
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Curious about the history of the manifold/trajectory view of neural activity.

My own first exposure was Gilles Laurent's chapter in "21 Problems in Systems Neuroscience", where he cites odor trajectories in locust AL (2005). This was v inspiring as a biophysics student studying dynamical systems...
February 21, 2025 at 7:11 PM
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Must-read for anyone interested in cognitive maps & the hippocampus.
1/12 How do animals build an internal map? In our new paper, we tracked thousands of mouse CA1 neurons over days/weeks as they learned a VR navigation task. @nspruston.bsky.social & co-1st author @johanwinn.bsky.social
Video: www.youtube.com/watch?v=yw_4...
Paper: www.nature.com/articles/s41...
Learning produces an orthogonalized state machine in the hippocampus
YouTube video by Weinan Sun
www.youtube.com
February 13, 2025 at 1:26 AM
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The NIH BRAIN Initiatives Impacts in Systems and Computational Neuroscience, 2014-2023 https://www.biorxiv.org/content/10.1101/2025.01.30.635684v1
February 1, 2025 at 1:15 PM
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As someone who has reported on AI for 7 years and covered China tech as well, I think the biggest lesson to be drawn from DeepSeek is the huge cracks it illustrates with the current dominant paradigm of AI development. A long thread. 1/
January 27, 2025 at 2:12 PM
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New book "Explanation in Biology" with Cambridge University Press is out & open access!

Covers (1) causal explanation & (2) non-causal/mathematical explanation in life sciences--bio, neuro, etc 🌿🧬🧠

Introduction to philosophical work on scientific explanation!

www.cambridge.org/core/element...
January 21, 2025 at 3:23 PM
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Ever wanted to do deep learning with a neural net that is one-to-one mapped to 65.05% of the fruit fly brain? 😄

Before this year ends, I will quickly advertise our code release of `flyvis.`

Docs: t.ly/YqWzR
Repo: t.ly/pMWpp

Work with @jakhmack.bsky.social, @srinituraga.bsky.social and colleagues
December 30, 2024 at 8:38 PM
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AI grad students: spend the summer imbedded in the neuroscience / neuroAI community at CSHL

Apply now for a paid summer internship !
Are you a grad student in AI interested in neuroscience and neuroAI?

Become a summer neuroAI intern at CSHL!

www.schooljobs.com/careers/cshl...
December 11, 2024 at 2:25 PM
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Three must read papers for PhD students. #scisky #PhD #science #research #academicsky

1. The importance of stupidity in scientific research

Open Access
journals.biologists.com/jcs/article/...
November 24, 2024 at 1:54 PM
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Excited to release what we’ve been working on at Amaranth Foundation, our latest whitepaper, NeuroAI for AI safety! A detailed, ambitious roadmap for how neuroscience research can help build safer AI systems while accelerating both virtual neuroscience and neurotech. 1/N
December 2, 2024 at 4:17 PM