Helmet Karim
@helmetkarim.bsky.social
Assistant professor of Psychiatry and Bioengineering at University of Pittsburgh
Reposted by Helmet Karim
Preprint is now published: doi.org/10.1002/hbm....
Special thanks to co-authors @twktan.bsky.social @kimnganngt.bsky.social @csabaorban.bsky.social
Special thanks to co-authors @twktan.bsky.social @kimnganngt.bsky.social @csabaorban.bsky.social
November 4, 2025 at 12:32 AM
Preprint is now published: doi.org/10.1002/hbm....
Special thanks to co-authors @twktan.bsky.social @kimnganngt.bsky.social @csabaorban.bsky.social
Special thanks to co-authors @twktan.bsky.social @kimnganngt.bsky.social @csabaorban.bsky.social
Reposted by Helmet Karim
Excellent commentary from Haroon & Miller on our REMBRANDT late-life depression study led by Andrew Gerlach (www.nature.com/articles/s41...)
www.nature.com/articles/s41...
www.nature.com/articles/s41...
July 7, 2025 at 2:30 PM
Excellent commentary from Haroon & Miller on our REMBRANDT late-life depression study led by Andrew Gerlach (www.nature.com/articles/s41...)
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Helmet Karim
This study explored relapse & recurrence in late-life depression, finding widespread 🧠 network configuration was required for resilience, while failure to reconfigure was associated w/ vulnerability to relapse
www.nature.com/artic...
www.nature.com/artic...
Network homeostasis: functional brain network alterations and relapse in remitted late-life depression
Neuropsychopharmacology - Network homeostasis: functional brain network alterations and relapse in remitted late-life depression
www.nature.com
July 2, 2025 at 6:28 PM
This study explored relapse & recurrence in late-life depression, finding widespread 🧠 network configuration was required for resilience, while failure to reconfigure was associated w/ vulnerability to relapse
www.nature.com/artic...
www.nature.com/artic...
A recent study investigated the role of repetitive transcranial magnetic stimulation (rTMS) in sustaining remission in patients with treatment-resistant depression.
Full article: jamanetwork.com/journals/jam...
Full article: jamanetwork.com/journals/jam...
June 24, 2025 at 12:04 PM
A recent study investigated the role of repetitive transcranial magnetic stimulation (rTMS) in sustaining remission in patients with treatment-resistant depression.
Full article: jamanetwork.com/journals/jam...
Full article: jamanetwork.com/journals/jam...
A recent study explored the effects of low-intensity transcranial focused ultrasound (LIFU) on amygdala activation during emotional processing. Utilizing MRI-guided LIFU, researchers aimed to modulate the amygdala's response to emotional stimuli.
June 23, 2025 at 5:50 PM
A recent study explored the effects of low-intensity transcranial focused ultrasound (LIFU) on amygdala activation during emotional processing. Utilizing MRI-guided LIFU, researchers aimed to modulate the amygdala's response to emotional stimuli.
Reposted by Helmet Karim
New finding! 5-day accelerated TMS (no MRI needed) showed major PTSD symptom relief in n~100 Veterans—77% response, 62% remission. Fast, scalable, and effective with scalp-based targeting. A big step for accessible PTSD care. 👉 www.sciencedirect.com/science/arti... #TMS #PTSD
Pragmatic Accelerated Transcranial Magnetic Stimulation for Posttraumatic Stress Disorder
www.sciencedirect.com
May 12, 2025 at 11:49 AM
New finding! 5-day accelerated TMS (no MRI needed) showed major PTSD symptom relief in n~100 Veterans—77% response, 62% remission. Fast, scalable, and effective with scalp-based targeting. A big step for accessible PTSD care. 👉 www.sciencedirect.com/science/arti... #TMS #PTSD
I encourage everyone to visit this site 5calls.org/all/. Make your calls to your representatives to make your voice heard.
Highly encourage everyone to call about recent scientific funding changes: 5calls.org/issue/nih-ns....
Highly encourage everyone to call about recent scientific funding changes: 5calls.org/issue/nih-ns....
All topics ⭑ 5 Calls
Spend 5 minutes. Make 5 calls. Make your voice heard.
5calls.org
February 10, 2025 at 1:26 AM
I encourage everyone to visit this site 5calls.org/all/. Make your calls to your representatives to make your voice heard.
Highly encourage everyone to call about recent scientific funding changes: 5calls.org/issue/nih-ns....
Highly encourage everyone to call about recent scientific funding changes: 5calls.org/issue/nih-ns....
Reposted by Helmet Karim
New essay on NIH and indirect costs:
goodscience.substack.com/p/indirect-c...
goodscience.substack.com/p/indirect-c...
Indirect Costs at NIH . . .
I wasn’t planning on spending part of a Saturday writing about cost accounting principles and the like, but NIH-world was hit with a doozy of a policy announcement on Friday night:
goodscience.substack.com
February 8, 2025 at 11:53 PM
New essay on NIH and indirect costs:
goodscience.substack.com/p/indirect-c...
goodscience.substack.com/p/indirect-c...
Reposted by Helmet Karim
Instead of cutting costs for working families, Donald Trump is slashing the federal investments that fund their lifesaving care, fuel their local economy, and lower their health care costs.
It’s cruel, short-sighted, and will cost jobs and devastate millions of families.
It’s cruel, short-sighted, and will cost jobs and devastate millions of families.
NIH cuts billions of dollars in biomedical funding, effective immediately
Researchers say it would hurt facilities that work on medical issues such as cancer research and heart disease. Elon Musk contends the old policy was ‘a ripoff.’
www.washingtonpost.com
February 8, 2025 at 10:06 PM
Instead of cutting costs for working families, Donald Trump is slashing the federal investments that fund their lifesaving care, fuel their local economy, and lower their health care costs.
It’s cruel, short-sighted, and will cost jobs and devastate millions of families.
It’s cruel, short-sighted, and will cost jobs and devastate millions of families.
Reposted by Helmet Karim
Another banger from the REMBRANDT study!
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Brain and cardiovascular responses to acute stress in remitted and recurrent late-life depression - Neuropsychopharmacology
Neuropsychopharmacology - Brain and cardiovascular responses to acute stress in remitted and recurrent late-life depression
www.nature.com
February 6, 2025 at 7:45 PM
Another banger from the REMBRANDT study!
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Helmet Karim
Hi Bluesky!
I'm Noah Schweitzer, a 5th year Bioengineering PhD candidate at the University of Pittsburgh. I will be wrapping up my dissertation this summer, focusing on sex-specific vascular dysfunction in AD in humans and mice. I'll soon be on the hunt for postdoc positions so I'm happy to connect🤠
I'm Noah Schweitzer, a 5th year Bioengineering PhD candidate at the University of Pittsburgh. I will be wrapping up my dissertation this summer, focusing on sex-specific vascular dysfunction in AD in humans and mice. I'll soon be on the hunt for postdoc positions so I'm happy to connect🤠
January 9, 2025 at 7:22 PM
Hi Bluesky!
I'm Noah Schweitzer, a 5th year Bioengineering PhD candidate at the University of Pittsburgh. I will be wrapping up my dissertation this summer, focusing on sex-specific vascular dysfunction in AD in humans and mice. I'll soon be on the hunt for postdoc positions so I'm happy to connect🤠
I'm Noah Schweitzer, a 5th year Bioengineering PhD candidate at the University of Pittsburgh. I will be wrapping up my dissertation this summer, focusing on sex-specific vascular dysfunction in AD in humans and mice. I'll soon be on the hunt for postdoc positions so I'm happy to connect🤠
Reposted by Helmet Karim
Felix’ story is devastating, relatable, and underlines why we should be concerned about psychedelic hype:
www.paperlesspost.com/go/7BbrzXXhb...
www.paperlesspost.com/go/7BbrzXXhb...
You're invited to "Farewell, Felix." Tap here to RSVP - Paperless Post Flyer
We are all devastated by Felix’s untimely death on 5th December 2024. He had been struggling with severe mental illness since early 2023.
There will be a funeral on 11th January in north London which...
www.paperlesspost.com
January 5, 2025 at 12:35 PM
Felix’ story is devastating, relatable, and underlines why we should be concerned about psychedelic hype:
www.paperlesspost.com/go/7BbrzXXhb...
www.paperlesspost.com/go/7BbrzXXhb...
Reposted by Helmet Karim
Hi all! This is Layla Banihashemi, Associate Professor of Psychiatry & BioE at Pitt. I'm a neuroscientist researching stress-control circuits and their relationships with adversity & trauma. Come find me All the way in the back (😄) at poster W300 sharing new data from our 7T R01 study! #ACNP2024
We are officially on the ground in Phoenix so it's time for the #ACNP2024 role call 📣
Introduce yourself, your science, tell us if you're a veteran or first-timer, promote your poster/talk/favorite social - whatever you want, this is your space to say it ⬇️
Introduce yourself, your science, tell us if you're a veteran or first-timer, promote your poster/talk/favorite social - whatever you want, this is your space to say it ⬇️
a poster of a witch and a girl with the words say something
ALT: a poster of a witch and a girl with the words say something
media.tenor.com
December 11, 2024 at 5:17 PM
Hi all! This is Layla Banihashemi, Associate Professor of Psychiatry & BioE at Pitt. I'm a neuroscientist researching stress-control circuits and their relationships with adversity & trauma. Come find me All the way in the back (😄) at poster W300 sharing new data from our 7T R01 study! #ACNP2024
Hey #ACNP2024, come check out our poster tonight (M78) on using cTBS to modulate nucleus accumbens to dmPFC connectivity and its effects on positive affect. See our blue sky poster (it's a 1 minute gif)!
December 9, 2024 at 11:45 PM
Hey #ACNP2024, come check out our poster tonight (M78) on using cTBS to modulate nucleus accumbens to dmPFC connectivity and its effects on positive affect. See our blue sky poster (it's a 1 minute gif)!
Reposted by Helmet Karim
Hey #ACNP2024, I’m Andrew Gerlach, Asst. Prof. of psychiatry at Pitt studying late life depression and anxiety, primarily with MRI. If you’re still around on Wednesday afternoon, stop by poster 82 to chat about the intrinsic networks and involved in antidepressant placebo response!
We are officially on the ground in Phoenix so it's time for the #ACNP2024 role call 📣
Introduce yourself, your science, tell us if you're a veteran or first-timer, promote your poster/talk/favorite social - whatever you want, this is your space to say it ⬇️
Introduce yourself, your science, tell us if you're a veteran or first-timer, promote your poster/talk/favorite social - whatever you want, this is your space to say it ⬇️
a poster of a witch and a girl with the words say something
ALT: a poster of a witch and a girl with the words say something
media.tenor.com
December 8, 2024 at 4:06 PM
Hey #ACNP2024, I’m Andrew Gerlach, Asst. Prof. of psychiatry at Pitt studying late life depression and anxiety, primarily with MRI. If you’re still around on Wednesday afternoon, stop by poster 82 to chat about the intrinsic networks and involved in antidepressant placebo response!
Hi I'm Helmet Karim, I'm an assistant professor of Psychiatry at U. Of Pittsburgh. Come see my hot topics talk at 5p tonight or my poster M78 on dmpfc TMS!
We are officially on the ground in Phoenix so it's time for the #ACNP2024 role call 📣
Introduce yourself, your science, tell us if you're a veteran or first-timer, promote your poster/talk/favorite social - whatever you want, this is your space to say it ⬇️
Introduce yourself, your science, tell us if you're a veteran or first-timer, promote your poster/talk/favorite social - whatever you want, this is your space to say it ⬇️
a poster of a witch and a girl with the words say something
ALT: a poster of a witch and a girl with the words say something
media.tenor.com
December 8, 2024 at 11:48 PM
Hi I'm Helmet Karim, I'm an assistant professor of Psychiatry at U. Of Pittsburgh. Come see my hot topics talk at 5p tonight or my poster M78 on dmpfc TMS!
Reposted by Helmet Karim
Excited for @helmetkarim.bsky.social ‘s hot topic talk on TMS at #ACNP2024!
December 8, 2024 at 11:01 PM
Excited for @helmetkarim.bsky.social ‘s hot topic talk on TMS at #ACNP2024!
Reposted by Helmet Karim
✨Our paper is out in Nature today! ✨
In this work, we investigated how we can leverage study designs to improve the replicability of brain-wide association studies (BWAS)
👇👇👇
www.nature.com/articles/s41...
In this work, we investigated how we can leverage study designs to improve the replicability of brain-wide association studies (BWAS)
👇👇👇
www.nature.com/articles/s41...
Study design features increase replicability in brain-wide association studies - Nature
Optimizing study design is critical for increasing standardized effect sizes and replicability, and the features that increase replicability in cross-sectional and longitudinal brain-wide association ...
www.nature.com
November 28, 2024 at 2:20 AM
✨Our paper is out in Nature today! ✨
In this work, we investigated how we can leverage study designs to improve the replicability of brain-wide association studies (BWAS)
👇👇👇
www.nature.com/articles/s41...
In this work, we investigated how we can leverage study designs to improve the replicability of brain-wide association studies (BWAS)
👇👇👇
www.nature.com/articles/s41...
Reposted by Helmet Karim
