Helen Grimsley
@helengrimsley.bsky.social
Postdoc, Powell lab
Memorial Sloan Kettering
🧬 DNA repair, replication, drug resistance 🧬
Memorial Sloan Kettering
🧬 DNA repair, replication, drug resistance 🧬
The expression or phosphorylation of 4E–BP1 and eIF4E may serve as predictive biomarkers to guide use of capivasertib in the clinic.
October 14, 2025 at 11:24 AM
The expression or phosphorylation of 4E–BP1 and eIF4E may serve as predictive biomarkers to guide use of capivasertib in the clinic.
Targeting the eIF4F complex may offer a promising strategy to overcome acquired Capivarsertib resistance.
October 14, 2025 at 11:24 AM
Targeting the eIF4F complex may offer a promising strategy to overcome acquired Capivarsertib resistance.
We also developed Single Molecule Analysis of ssDNA gaps (SMAss) that quantitatively resolved ssDNA gap dynamics.
October 8, 2025 at 12:58 PM
We also developed Single Molecule Analysis of ssDNA gaps (SMAss) that quantitatively resolved ssDNA gap dynamics.
Reposted by Helen Grimsley
Reposted by Helen Grimsley
