Max Heiman
@heiman.bsky.social
Associate Professor of Genetics
Harvard Medical School, Boston Children's Hospital
It should be fun, or what's the point?
http://heimanlab.com
Harvard Medical School, Boston Children's Hospital
It should be fun, or what's the point?
http://heimanlab.com
I agree, I think CGC dues us probably the best proxy - hadn't thought of that before
November 7, 2025 at 10:43 PM
I agree, I think CGC dues us probably the best proxy - hadn't thought of that before
that's good as a high end probably, I think that's more like all the labs that have ever been (minus a smaller number without lab codes). consistent with a guess of around 500-800ish currently?
November 7, 2025 at 10:36 PM
that's good as a high end probably, I think that's more like all the labs that have ever been (minus a smaller number without lab codes). consistent with a guess of around 500-800ish currently?
That's about what I guesstimated but nice to hear you thinking that way too. I got there because I think I remember there were ~200ish R01s ~ten years ago (before R35 shift), some people had more than one, some had NSF/other, many non-US, but ~500-750 (1000 at high end) seemed like a good guess.
November 7, 2025 at 10:35 PM
That's about what I guesstimated but nice to hear you thinking that way too. I got there because I think I remember there were ~200ish R01s ~ten years ago (before R35 shift), some people had more than one, some had NSF/other, many non-US, but ~500-750 (1000 at high end) seemed like a good guess.
Not sure - paper, preprint, or research grant (incl. startup) in last 5 years?
I guess CGC annual dues could be a good estimate too.
I guess CGC annual dues could be a good estimate too.
November 7, 2025 at 10:32 PM
Not sure - paper, preprint, or research grant (incl. startup) in last 5 years?
I guess CGC annual dues could be a good estimate too.
I guess CGC annual dues could be a good estimate too.
I mean, it's pretty clear. It refers to peer review members disclosing any information about the applications being reviewed.
It's clearly not limiting the guidance NIH can provide or the general freedom of people to complain about typos etc as long as it's not connected to the apps they review.
It's clearly not limiting the guidance NIH can provide or the general freedom of people to complain about typos etc as long as it's not connected to the apps they review.
November 3, 2025 at 5:15 PM
I mean, it's pretty clear. It refers to peer review members disclosing any information about the applications being reviewed.
It's clearly not limiting the guidance NIH can provide or the general freedom of people to complain about typos etc as long as it's not connected to the apps they review.
It's clearly not limiting the guidance NIH can provide or the general freedom of people to complain about typos etc as long as it's not connected to the apps they review.
In my view it's 100% a breach of confidentiality and review integrity.
"Confidentiality in NIH peer review prohibits a peer reviewer member from: [...]
Disclosing, **in any manner**, information about the committee deliberations, discussions, evaluations, or documents [...]"
emphasis added
"Confidentiality in NIH peer review prohibits a peer reviewer member from: [...]
Disclosing, **in any manner**, information about the committee deliberations, discussions, evaluations, or documents [...]"
emphasis added
November 3, 2025 at 4:01 PM
In my view it's 100% a breach of confidentiality and review integrity.
"Confidentiality in NIH peer review prohibits a peer reviewer member from: [...]
Disclosing, **in any manner**, information about the committee deliberations, discussions, evaluations, or documents [...]"
emphasis added
"Confidentiality in NIH peer review prohibits a peer reviewer member from: [...]
Disclosing, **in any manner**, information about the committee deliberations, discussions, evaluations, or documents [...]"
emphasis added
Reposted by Max Heiman
From the lab of Maxwell Heiman discussing the interesting topic of apical ECM and the function of sensing organs and how these ECM proteins can both mechanically and biochemically modulate the organ's functions.
doi.org/10.1016/j.cd...
doi.org/10.1016/j.cd...
October 30, 2025 at 5:48 PM
From the lab of Maxwell Heiman discussing the interesting topic of apical ECM and the function of sensing organs and how these ECM proteins can both mechanically and biochemically modulate the organ's functions.
doi.org/10.1016/j.cd...
doi.org/10.1016/j.cd...
hey are you stopping by? longwood area worm meeting is tomorrow! come hang out
October 27, 2025 at 10:07 PM
hey are you stopping by? longwood area worm meeting is tomorrow! come hang out
...or non-robustness! Idea reminds me of Etchberger et al 2008 doi.org/10.1242/dev.... that showed (I'm oversimplifying) promoters with ideal consensus sites are high affinity and constitutive, those with less-ideal sites are low affinity and expressed conditionally (require co-factors for binding).
October 22, 2025 at 8:59 AM
...or non-robustness! Idea reminds me of Etchberger et al 2008 doi.org/10.1242/dev.... that showed (I'm oversimplifying) promoters with ideal consensus sites are high affinity and constitutive, those with less-ideal sites are low affinity and expressed conditionally (require co-factors for binding).
and when I say "we", I actually mean an amazing Bard College undergrad Kaitlyn Choi who did it as her senior thesis project, and who I got to remotely mentor by email as a postdoc
October 15, 2025 at 11:34 PM
and when I say "we", I actually mean an amazing Bard College undergrad Kaitlyn Choi who did it as her senior thesis project, and who I got to remotely mentor by email as a postdoc
1. How is the C. elegans community so consistently amazing with 0.5% of R01s?
2. Is that post-2015 drop-off just a migration to R35s or a real change in NIH funding allocation?
2. Is that post-2015 drop-off just a migration to R35s or a real change in NIH funding allocation?
October 11, 2025 at 9:19 PM
1. How is the C. elegans community so consistently amazing with 0.5% of R01s?
2. Is that post-2015 drop-off just a migration to R35s or a real change in NIH funding allocation?
2. Is that post-2015 drop-off just a migration to R35s or a real change in NIH funding allocation?