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Huntington’s disease research news. In plain language. Written by scientists. hdbuzz.net
Editors - @sjh508 @rjharding
To close out 2025, we're celebrating those who move Huntington's disease research forward, from scientists to families, closing this year with the gratitude we feel for the HD community.
November 11, 2025 at 5:18 PM
November 10, 2025 at 4:28 PM
October 25, 2025 at 3:43 PM
October 20, 2025 at 2:02 PM
Chris shared this slide, summarizing the complexities of biomarkers. #HDCongress2025
October 13, 2025 at 9:14 PM
The incomparable Dr. Nancy Wexler has been a driving force for advancing HD research. #HDCongress2025
October 13, 2025 at 7:56 PM
Oh look, Dr. Ed Wild, HDBuzz Editor Emeritus and co-founder, made an appearance too. #HDCongress2025
October 13, 2025 at 6:37 PM
Now we're hearing from someone avid HDBuzz readers will know well, Dr. Jeff Carroll. #HSCongress2025
October 13, 2025 at 6:36 PM
October 13, 2025 at 4:57 PM
October 13, 2025 at 3:25 PM
He cautions providers in the room to be careful about their language in the clinic, to avoid making folks feel excluded when discussing clinical trials. This is particularly important for the HD-ISS because it is currently a research tool, not a clinical classification for HD. #HDCongress2025
October 13, 2025 at 2:31 PM
HDBuzz is front and center for Day 3 of #HDCongress2025 to bring you updates!
October 13, 2025 at 2:20 PM
The audience loved his visual to explain how he used to think about academia as a magical world, versus his stark idea of industry, and how that thinking has evolved to one of partnership through innovation and exploration. #HDCongress2025
October 12, 2025 at 7:29 PM
New data from Skyhawk! #HDCongress2025
October 12, 2025 at 4:54 PM
October 12, 2025 at 4:29 PM
Novartis' Phase 3 trial design for votoplam. #HDCongress2025
October 12, 2025 at 4:27 PM
The most important graphs shows that for people who received AMT-130, their HD symptoms progressed more slowly 3 years after the initial surgery - based on how much their scores on thinking, function, and movement tests changed over time compared to a control group. #HDCongress2025
October 11, 2025 at 6:42 PM
October 11, 2025 at 6:34 PM
uniQure reports promising results from a key clinical study, showing that its experimental gene therapy, AMT-130, may slow the progress of Huntington's disease

en.hdbuzz.net/the-first-do...
September 24, 2025 at 6:01 PM
Pridopidine has been studied for decades as a possible treatment for Huntington’s disease. The PROOF-HD trial didn’t meet its primary goals, but its full results are now published—making valuable data available for the HD community.

en.hdbuzz.net/proof-in-the...
September 10, 2025 at 4:39 PM
From gut microbes to muscle health, August’s HD research uncovered new biomarkers, protein maps, and lifestyle clues. Each finding brings us closer to earlier detection and smarter treatments.

Full Article: en.hdbuzz.net/august-2025-...
August 28, 2025 at 2:18 PM
The gut and brain talk nonstop along a busy two-way superhighway. In Huntington’s disease, this route can get jammed, rerouted, or even carry harmful cargo — connecting gut microbes, inflammation, and brain health in unexpected ways.

en.hdbuzz.net/the-gut-brai...
August 15, 2025 at 11:12 AM
August 12, 2025 at 2:59 PM
Huntington’s isn’t just a brain disease — it affects the whole body. New research shows that muscle, fat, and nutrition changes can happen early in HD, even before symptoms are obvious. Keeping an eye on these shifts could help to receive better care.

Full Article: shorturl.at/j0Xgc
August 7, 2025 at 4:10 PM
Today we're spotlighting an article from April 2025 highlighting how research links antidepressant use to faster cognitive decline in people with dementia, but don’t jump to conclusions for Huntington’s disease. HD is different, and more research is needed before applying these findings.
August 6, 2025 at 7:43 PM