Han Kim
hankimlab.bsky.social
Han Kim
@hankimlab.bsky.social
Heart, fat, Irx, development and metabolism. Scientist and Associate Professor @HeartInstitute @uOttawa
Reposted by Han Kim
I am happy to share the latest preprint from our lab (@ircm.bsky.social, @umontreal.ca, @mcgill.ca) exploring why and how the liver gets fatty when you are fasting, and how this could impact MASLD.

www.biorxiv.org/content/10.1...

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Glucagon-induced PGC-1α4/PPARγ promotes hepatic lipid storage and macrosteatosis in fasting and MASLD
The liver plays a central role in regulating the transition between fasting and feeding states, coordinating glycogen breakdown, gluconeogenesis, fatty acid catabolism, and lipid storage. Disruptions ...
www.biorxiv.org
September 26, 2025 at 2:43 PM