Jennifer Estall
dnachicken.bsky.social
Jennifer Estall
@dnachicken.bsky.social
Diabetes Researcher, Canadian, mother of dragons
I am happy to share the latest preprint from our lab (@ircm.bsky.social, @umontreal.ca, @mcgill.ca) exploring why and how the liver gets fatty when you are fasting, and how this could impact MASLD.

www.biorxiv.org/content/10.1...

🧵1/6
Glucagon-induced PGC-1α4/PPARγ promotes hepatic lipid storage and macrosteatosis in fasting and MASLD
The liver plays a central role in regulating the transition between fasting and feeding states, coordinating glycogen breakdown, gluconeogenesis, fatty acid catabolism, and lipid storage. Disruptions ...
www.biorxiv.org
September 26, 2025 at 2:43 PM
Just thought I would share this recent study in 2.5M children, if people want to see some of the research. Spoiler: No association was found. Acetaminophen Use During Pregnancy and Children’s Risk of Autism, ADHD, and Intellectual Disability url: jamanetwork.com/journals/jam...
Acetaminophen Use During Pregnancy and Children’s Risk of Autism, ADHD, and Intellectual Disability
This nationwide cohort study with sibling control analysis examines the association of acetaminophen use during pregnancy with children’s risk of autism, ADHD, and intellectual disability.
jamanetwork.com
September 24, 2025 at 5:19 PM
Reposted by Jennifer Estall
September 15, 2025 at 8:57 PM
Reposted by Jennifer Estall
🧵(2/3) Cont' beginning of Sept 2025:
2) “Glycerol and glycerol-3-phosphate: multifaceted metabolites in metabolism, cancer and other diseases” PMID: 40927981
3) “Osteocalcin has many tricks to get γ-carboxylated” PMID: 40913186
Links in last thread
September 15, 2025 at 8:57 PM
Reposted by Jennifer Estall
🧵(1/3) Our first post highlighting publications coming from CIRTN groups (first half of September 2025)! We have works from the labs of Drs. Marc Prentki, Timothy Kieffer and Mathieu Ferron.
1)“From β soloist to endocrine symphony: Subtype-complete islets conduct glucose harmony” PMID 40912231
September 15, 2025 at 8:57 PM
An amazing line up, as always! This is a highly recommended conference for anyone in metabolism.
Can't wait for the Sable Award Lecture at #METPHYS2025

Which one of these stellar scientists get's your vote for this years award?

The Sable Award recognizes Outstanding Contributions to the field of Metabolic Physiology

Registration closes April 15
www.sablesys.com/metphys2025-...
April 11, 2025 at 9:53 PM