Additionally, Tsirkas et al. show that R-loops, under specific conditions, can be beneficial for cells, by reducing excessive RNAPII load on highly-transcribing genes, thus preventing potential TRCs.

We are very happy to see this project led by @ioannistsirkas.bsky.social reach the final stages! 🥳

Wishing you all the best as you move on to your next adventure, we are so proud of you! It’s been great having you in the lab — we’ll miss you!

Thank you, Umberto!

Happy to hear it, thank you Marcelo!

Thank you, Daphne!