Gyunghee Jo
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gyungheejo.bsky.social
Gyunghee Jo
@gyungheejo.bsky.social
Postdoc at Scripps Research - Ward lab
Published back-to-back with a beautifully done study by Lederhofer & Borst et al., who identified antibodies with a similar recurring motif and explored their function through structural and in vivo studies🧪🐁
doi.org/10.1038/s414...
Structural convergence and water-mediated substrate mimicry enable broad neuraminidase inhibition by human antibodies - Nature Communications
Monoclonal antibodies targeting the conserved neuraminidase catalytic site mimic sialic acid and use coordinated water molecules to inhibit diverse influenza A and B viruses, including H5N1, providing...
doi.org
August 2, 2025 at 6:03 PM