Gregg Thomas
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Gregg Thomas
@gwct.bio
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Bioinformatics Scientist at Harvard FAS Informatics. Evolution, Genomics, Phylogenetics. Dog walker. He/him. gwct.bio // informatics.fas.harvard.edu
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Great to work with @ekopania.bsky.social, @jeffreygood.bsky.social, and everyone else on this project! I was happy to be able to present Emily's cool figure showing dN/dS of genes in different tissues and different time-points at Evolution a couple years ago:
A color figure (3) from the paper linked in the quoted post. The top panel A shows a drawing of the male rodent reproductive tract with different tissues shaded different colors, from dark blue to red, indicating median dN/dS values for genes expressed in those tissues. Below are colored cells using the same color scale from five different stages of spermatogenesis. Panels B and C below are graphs with points on the x-axise corresponding to the four cell stages shown above, with the y-axis for panel B being the proportion of genes under positive selection for each time point and for panel C being the proportion of genes expressed during that stage that are testis-specific. The points in panel B hover around the genome-wide average shown with a dotted horizontal line, while the points in panel C increase steadily above the genome-wide average, peaking in stage 4 (spermatids).
November 14, 2024 at 7:44 PM