Shuaiqi Guo
guo-lab.bsky.social
Shuaiqi Guo
@guo-lab.bsky.social
Assistant Professor of Anatomy and Cell Biology at McGill University in Montreal, Canada

Microbial motility, adhesion, biofilm formation, cryo-FIB, cryo-ET.
Happy to share a nice story lead by graduate student @mingyu-wang.bsky.social who designed very short peptides that disrupt Vibrio cholerae adhesion to human tissues. Great collaboration with the Lubell (Montreal), Klose (UTSA) and Davies (Queen's) labs.

febs.onlinelibrary.wiley.com/doi/10.1002/...
November 25, 2025 at 6:56 PM
Reposted by Shuaiqi Guo
As mentioned, here is the preprint by Jensen and @viollierpat.bsky.social on the in situ structure of the Tad pilus. www.biorxiv.org/content/10.1.... Nice work and great to see that we are seeing the same thing! Our preprint: www.biorxiv.org/content/10.1... #microsky
Great collaboration with @guo-lab.bsky.social to determine an in situ architectural model of the Tad pilus machine. Be on the lookout soon for a preprint on the same topic by Grant Jensen and @viollierpat.bsky.social. #microsky
November 8, 2025 at 7:35 PM
Great collaboration with @brunlabcaulo.bsky.social for resolving the Tad pilus machine structure by cryo-ET. Beautiful work by graduate students James Iarocci and Ryu Williston in our lab.

Preprint:https://www.biorxiv.org/content/10.1101/2025.11.05.686773v1
November 6, 2025 at 3:58 PM
Reposted by Shuaiqi Guo
Great collaboration with @guo-lab.bsky.social to determine an in situ architectural model of the Tad pilus machine. Be on the lookout soon for a preprint on the same topic by Grant Jensen and @viollierpat.bsky.social. #microsky
November 6, 2025 at 3:51 PM
Reposted by Shuaiqi Guo
Structure of the Pseudomonas aeruginosa PAO1 Type IV pilus
Finally out in PLOS Pathogens. Congrats Hannah Ochner and co-authors. @mrclmb.bsky.social

journals.plos.org/plospathogen...
December 16, 2024 at 3:53 PM