Thank you for your kind words Marcin!

It's not exactly the same thing: the preprint reports a state found while preparing the case study, but not reported in the case study. 😉

An interesting opinion here (on an instance of the social network we should all be using 😉): neuromatch.social/@neuralrecko...

I agree about the diminishing need for journals. But can't we do this without AI? Shouldn't we be doing this without AI, even?

Corporate journals giving us one more reason to submit our papers to society journals instead.

Not even: is some crystal structures (I think including the original 1AOI), the tail of H4 binds to the acidic patch of another nucleosome in the neighboring unit cell. 🧬🙃🧬

Some pioneer TFs.
A good review about factors binding to the acidic patch: doi.org/10.1016/j.sb...
A few years ago I looked for a conserved acidic patch binding sequence motif, but found that there didn't seem to be any: the only common residue was the Arg anchor. Maybe time to revisit this?

This is impressive! And very helpful to the whole community, so thanks a lot for taking the time to make it work and sharing the results!
(But also not thank you: I really didn't need one more distraction in a busy fall semester... 😅 I have a dataset with a very small protein lying around...)

Great point. Make it opt out, not opt in, for authors to see feedback.

We need to grow a culture of rapid and constructive feedback to replace ‘peer review’… which is outdated, was not designed and is not fit for purpose.

How can we do that if public reviews are not even seen by the authors?

How exactly do you set up the remove duplicates job to answer this question?
I have a similar case: different conformations of a hexameric (D3) complex, and I'd like to know if the different conformations of the subunits (found by symexp and 3D classification) can occur in the same hexamer or not.

Thanks for sharing @olibclarke.bsky.social. I wonder if many more "hollow" complexes are co-purified with binding-partners. Let's all put more datasets on EMPIAR to revisit processing with new creative approaches like Oli's.

It's one of the best time investments I've made. Great for making figures, posters, or any visual really. It even has a tool to make slides! (which produces a file that opens in a web browser, so can be displayed on any computer regardless of which presentation software is available).

Simple drawings are fine. But if you want to re-use and adapt your drawings later, you should really use a vector format, so not Paint nor Gimp (both raster editors). Inkscape is an excellent vector drawing program: inkscape.org
A bunch of others are listed here: en.wikipedia.org/wiki/Compari...

www.jiscmail.ac.uk/cgi-bin/wa-j...

Post this to CCPEM tomorrow. 👌 🍿