gsbardella.bsky.social
@gsbardella.bsky.social
Medicinal Chemist/Chemical Biologist; Professor at the University of Salerno; epigenetics; EFMC EC Secretary; ChemMedChem EB Chair; cooking, food, and wine lover; opinions are my own
ORCID: orcid.org/0000-0003-0748-1145
ORCID: orcid.org/0000-0003-0748-1145
Join @youngscinet.bsky.social for "Under Pressure: A Mental Health Conversation for the Academic Community," a virtual workshop aimed at building resilience, support and creating a healthier future for yourself and academia.
October 10 - 1PM
🔗 us06web.zoom.us/webinar/regi...
October 10 - 1PM
🔗 us06web.zoom.us/webinar/regi...
September 30, 2025 at 6:54 AM
Join @youngscinet.bsky.social for "Under Pressure: A Mental Health Conversation for the Academic Community," a virtual workshop aimed at building resilience, support and creating a healthier future for yourself and academia.
October 10 - 1PM
🔗 us06web.zoom.us/webinar/regi...
October 10 - 1PM
🔗 us06web.zoom.us/webinar/regi...
The new issue of #ChemMedChem (@chemistryeurope.bsky.social) is out (chemistry-europe.onlinelibrary.wiley.com/toc/18607187...) with a Front Cover illustrating the crystal structure of the N-terminal domain of clathrin with the known binding sites colored and a selection of Pitstop 2 analogues.
August 26, 2025 at 9:10 AM
The new issue of #ChemMedChem (@chemistryeurope.bsky.social) is out (chemistry-europe.onlinelibrary.wiley.com/toc/18607187...) with a Front Cover illustrating the crystal structure of the N-terminal domain of clathrin with the known binding sites colored and a selection of Pitstop 2 analogues.
An Highlight article just accepted in #ChemMedChem (@chemistryeurope.bsky.social) spotlights #balinatunfib, an orally available small molecule jointly developed by Sanofi and UCB preventing TNFα from effectively binding to its receptors.
chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/...
chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/...
June 21, 2025 at 9:27 AM
An Highlight article just accepted in #ChemMedChem (@chemistryeurope.bsky.social) spotlights #balinatunfib, an orally available small molecule jointly developed by Sanofi and UCB preventing TNFα from effectively binding to its receptors.
chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/...
chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/...
The new issue of #ChemMedChem (@chemistryeurope.bsky.social) is out (chemistry-europe.onlinelibrary.wiley.com/toc/18607187...)!
June 18, 2025 at 7:33 AM
The new issue of #ChemMedChem (@chemistryeurope.bsky.social) is out (chemistry-europe.onlinelibrary.wiley.com/toc/18607187...)!
The last talk of the day at the 11th Novalix Conference “Biophysics in Drug Discovery” was the terrific keynote lecture by Stefan Knapp on "Comprehensive Characterization of Chemical Tools and New Modalities such as PROTACs".
@thesgc.bsky.social
@thesgc.bsky.social
May 21, 2025 at 10:04 PM
The last talk of the day at the 11th Novalix Conference “Biophysics in Drug Discovery” was the terrific keynote lecture by Stefan Knapp on "Comprehensive Characterization of Chemical Tools and New Modalities such as PROTACs".
@thesgc.bsky.social
@thesgc.bsky.social
Amazing keynote lecture by Amanda Garner at the 11th Novalix Conference—Biophysics in Drug Discovery in Strasbourg.
Amanda delivered a brilliant talk on "Enabling Technologies for Revealing Druggable Paths in RNA Biology".
@acsmedi.bsky.social
Amanda delivered a brilliant talk on "Enabling Technologies for Revealing Druggable Paths in RNA Biology".
@acsmedi.bsky.social
May 21, 2025 at 9:59 PM
Amazing keynote lecture by Amanda Garner at the 11th Novalix Conference—Biophysics in Drug Discovery in Strasbourg.
Amanda delivered a brilliant talk on "Enabling Technologies for Revealing Druggable Paths in RNA Biology".
@acsmedi.bsky.social
Amanda delivered a brilliant talk on "Enabling Technologies for Revealing Druggable Paths in RNA Biology".
@acsmedi.bsky.social
Great talk by @mariaduca-cnrs.bsky.social at the 11th Novalix Conference about Biophysics in Drug Discovery. Maria presented a few of her group projects, talking on how to target RNA using synthetic small molecules and how to discover an characterize RNA binders. Brilliant!
May 21, 2025 at 9:56 PM
Great talk by @mariaduca-cnrs.bsky.social at the 11th Novalix Conference about Biophysics in Drug Discovery. Maria presented a few of her group projects, talking on how to target RNA using synthetic small molecules and how to discover an characterize RNA binders. Brilliant!
The new issue of #ChemMedChem (@chemistryeurope.bsky.social) is out!
chemistry-europe.onlinelibrary.wiley.com/toc/18607187...
chemistry-europe.onlinelibrary.wiley.com/toc/18607187...
May 21, 2025 at 9:53 PM
The new issue of #ChemMedChem (@chemistryeurope.bsky.social) is out!
chemistry-europe.onlinelibrary.wiley.com/toc/18607187...
chemistry-europe.onlinelibrary.wiley.com/toc/18607187...
An amazing, totally inspirational and emotional journey! The @acs.org Priestley Medal talk by @francesarnold.bsky.social at #ACSSpring2025
March 24, 2025 at 12:13 AM
An amazing, totally inspirational and emotional journey! The @acs.org Priestley Medal talk by @francesarnold.bsky.social at #ACSSpring2025
The new issue of #ChemMedChem (@chemistryeurope.bsky.social) is out!
chemistry-europe.onlinelibrary.wiley.com/toc/18607187...
chemistry-europe.onlinelibrary.wiley.com/toc/18607187...
March 9, 2025 at 9:27 PM
The new issue of #ChemMedChem (@chemistryeurope.bsky.social) is out!
chemistry-europe.onlinelibrary.wiley.com/toc/18607187...
chemistry-europe.onlinelibrary.wiley.com/toc/18607187...
A Career doing STUFF, a Guest Editorial by Mike Hann for the #ChemMedChem (@chemistryeurope.bsky.social) MedChem Musings series, summarises the many things he did during his 45 year-career in drug discovery. Practical advices and inspiration for future generations of researchers.
lnkd.in/dNNy7FaE
lnkd.in/dNNy7FaE
February 27, 2025 at 12:21 PM
A Career doing STUFF, a Guest Editorial by Mike Hann for the #ChemMedChem (@chemistryeurope.bsky.social) MedChem Musings series, summarises the many things he did during his 45 year-career in drug discovery. Practical advices and inspiration for future generations of researchers.
lnkd.in/dNNy7FaE
lnkd.in/dNNy7FaE
The new issue of #ChemMedChem (@chemistryeurope.bsky.social) is out!
chemistry-europe.onlinelibrary.wiley.com/toc/18607187...
chemistry-europe.onlinelibrary.wiley.com/toc/18607187...
February 21, 2025 at 7:58 AM
The new issue of #ChemMedChem (@chemistryeurope.bsky.social) is out!
chemistry-europe.onlinelibrary.wiley.com/toc/18607187...
chemistry-europe.onlinelibrary.wiley.com/toc/18607187...
Understanding of how structural elements impact #atropisomer stability enables the more efficient optimization of this important feature. A new manuscript just accepted in #ChemMedChem (@chemistryeurope.bsky.social)
chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/...
chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/...
February 5, 2025 at 10:01 PM
Understanding of how structural elements impact #atropisomer stability enables the more efficient optimization of this important feature. A new manuscript just accepted in #ChemMedChem (@chemistryeurope.bsky.social)
chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/...
chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/...
Concluding remarks by Claudia Höbartner at #EFMCISCB25. Thanks to sponsors, exhibitors, committees, secretariat and, above all, participants that made this event a very successful one. See you again in 2027!
@euromedchem.bsky.social
@youngscinet.bsky.social
@euromedchem.bsky.social
@youngscinet.bsky.social
January 31, 2025 at 11:14 PM
Concluding remarks by Claudia Höbartner at #EFMCISCB25. Thanks to sponsors, exhibitors, committees, secretariat and, above all, participants that made this event a very successful one. See you again in 2027!
@euromedchem.bsky.social
@youngscinet.bsky.social
@euromedchem.bsky.social
@youngscinet.bsky.social
An amazing KL by Akane Kawamura (@kawamuragroup.bsky.social) opened the session on “Chemical Biology of Chromatin and the Epitranscriptome” at #EFMCISCB25, chaired by Paola Arimondo. Akane thrilled the audience with her work on 2OG Oxygenases in Epigenetic Regulation.
@euromedchem.bsky.social
@euromedchem.bsky.social
January 31, 2025 at 9:57 AM
An amazing KL by Akane Kawamura (@kawamuragroup.bsky.social) opened the session on “Chemical Biology of Chromatin and the Epitranscriptome” at #EFMCISCB25, chaired by Paola Arimondo. Akane thrilled the audience with her work on 2OG Oxygenases in Epigenetic Regulation.
@euromedchem.bsky.social
@euromedchem.bsky.social
Chaired by Claudia Höbartner, the last day at #EFMCISCB25 starts with the PL by Cynthia Burrows (@uofupress.bsky.social) thrilling the audience with her nanopore studies on chemically modified RNA. @euromedchem.bsky.social
January 31, 2025 at 8:23 AM
Chaired by Claudia Höbartner, the last day at #EFMCISCB25 starts with the PL by Cynthia Burrows (@uofupress.bsky.social) thrilling the audience with her nanopore studies on chemically modified RNA. @euromedchem.bsky.social
The 2nd day at #EFMCISCB25 starts early with a Career Panel Discussion, featuring @stephanhacker2.bsky.social, @kawamuragroup.bsky.social, Cristoph Dumelin, and Thais Gazzi, chaired by Laia Josa Culleré.
@euromedchem.bsky.social
@youngscinet.bsky.social
@euromedchem.bsky.social
@youngscinet.bsky.social
January 30, 2025 at 7:08 AM
The 2nd day at #EFMCISCB25 starts early with a Career Panel Discussion, featuring @stephanhacker2.bsky.social, @kawamuragroup.bsky.social, Cristoph Dumelin, and Thais Gazzi, chaired by Laia Josa Culleré.
@euromedchem.bsky.social
@youngscinet.bsky.social
@euromedchem.bsky.social
@youngscinet.bsky.social
And now is the turn of @euromedchem.bsky.social President, @luvah.bsky.social, introducing EFMC and its many activities in the Medicinal Chemistry and Chemical Biology field and to cheer the attendees of #EFMCISCB25
January 29, 2025 at 1:14 PM
And now is the turn of @euromedchem.bsky.social President, @luvah.bsky.social, introducing EFMC and its many activities in the Medicinal Chemistry and Chemical Biology field and to cheer the attendees of #EFMCISCB25
And finally the #EFMCISCB25 is starting, opened by Uwe Grether, co-chair of the event together with Claudia Hobartner.
@euromedchem.bsky.social
@euromedchem.bsky.social
January 29, 2025 at 1:05 PM
And finally the #EFMCISCB25 is starting, opened by Uwe Grether, co-chair of the event together with Claudia Hobartner.
@euromedchem.bsky.social
@euromedchem.bsky.social
A β-glucuronidase-responsive albumin-binding prodrug programmed to release a potent Isocombretastatin A-4 analog within the tumor microenvironment.
Just accepted in #ChemMedChem @chemistryeurope.bsky.social
chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/...
Just accepted in #ChemMedChem @chemistryeurope.bsky.social
chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/...
January 28, 2025 at 9:55 PM
A β-glucuronidase-responsive albumin-binding prodrug programmed to release a potent Isocombretastatin A-4 analog within the tumor microenvironment.
Just accepted in #ChemMedChem @chemistryeurope.bsky.social
chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/...
Just accepted in #ChemMedChem @chemistryeurope.bsky.social
chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/...
Just arrived in Basel, ready for the @euromedchem.bsky.social #EFMCISCB25 starting tomorrow!
January 28, 2025 at 9:49 PM
Just arrived in Basel, ready for the @euromedchem.bsky.social #EFMCISCB25 starting tomorrow!
A new methodology to derive biomolecular structure ensembles from distance distribution measurements via a library of tagged proteins bound to an unlabeled and otherwise unmodified target biologic.
Just accepted in #ChemMedChem (@chemistryeurope.bsky.social)
lnkd.in/eAiqfVWa
Just accepted in #ChemMedChem (@chemistryeurope.bsky.social)
lnkd.in/eAiqfVWa
January 17, 2025 at 6:30 PM
A new methodology to derive biomolecular structure ensembles from distance distribution measurements via a library of tagged proteins bound to an unlabeled and otherwise unmodified target biologic.
Just accepted in #ChemMedChem (@chemistryeurope.bsky.social)
lnkd.in/eAiqfVWa
Just accepted in #ChemMedChem (@chemistryeurope.bsky.social)
lnkd.in/eAiqfVWa
The new issue of #ChemMedChem (@chemistryeurope.bsky.social) is out!
chemistry-europe.onlinelibrary.wiley.com/toc/18607187...
chemistry-europe.onlinelibrary.wiley.com/toc/18607187...
January 15, 2025 at 10:53 AM
The new issue of #ChemMedChem (@chemistryeurope.bsky.social) is out!
chemistry-europe.onlinelibrary.wiley.com/toc/18607187...
chemistry-europe.onlinelibrary.wiley.com/toc/18607187...
LAST CHANCE TO JOIN @euromedchem.bsky.social EFMC-ISCB 2025!
Do not miss this key event in chemical biology, already attracting over 225 participants! (www.efmc-iscb.org/speakers)
Day pass available. Register Now! (www.efmc-iscb.org/registration)
#EFMCISCB25
@youngscinet.bsky.social
Do not miss this key event in chemical biology, already attracting over 225 participants! (www.efmc-iscb.org/speakers)
Day pass available. Register Now! (www.efmc-iscb.org/registration)
#EFMCISCB25
@youngscinet.bsky.social
January 15, 2025 at 10:50 AM
LAST CHANCE TO JOIN @euromedchem.bsky.social EFMC-ISCB 2025!
Do not miss this key event in chemical biology, already attracting over 225 participants! (www.efmc-iscb.org/speakers)
Day pass available. Register Now! (www.efmc-iscb.org/registration)
#EFMCISCB25
@youngscinet.bsky.social
Do not miss this key event in chemical biology, already attracting over 225 participants! (www.efmc-iscb.org/speakers)
Day pass available. Register Now! (www.efmc-iscb.org/registration)
#EFMCISCB25
@youngscinet.bsky.social