Griffiths Lab
@griffithslab.bsky.social
Discovering the remarkable intracellular dynamics of killer T cells
Reposted by Griffiths Lab
New JCS snapshot - Cytotoxic T lymphocytes adapt to the loss of Cdc42
@adamrochussen.bsky.social presents the key findings from their recent JCS paper with Claire Ma and Gillian Griffiths @griffithslab.bsky.social.
journals.biologists.com/jcs/article/...
@adamrochussen.bsky.social presents the key findings from their recent JCS paper with Claire Ma and Gillian Griffiths @griffithslab.bsky.social.
journals.biologists.com/jcs/article/...
September 10, 2025 at 3:23 PM
New JCS snapshot - Cytotoxic T lymphocytes adapt to the loss of Cdc42
@adamrochussen.bsky.social presents the key findings from their recent JCS paper with Claire Ma and Gillian Griffiths @griffithslab.bsky.social.
journals.biologists.com/jcs/article/...
@adamrochussen.bsky.social presents the key findings from their recent JCS paper with Claire Ma and Gillian Griffiths @griffithslab.bsky.social.
journals.biologists.com/jcs/article/...
Sometimes, knocking out a gene isn't a good way to figure out the function of that gene ...
In our new @jcellsci.bsky.social paper, we report potent transcriptional adaptation by cytotoxic T lymphocytes (CTLs) in response to CRISPR/Cas9-mediated deletion of the important polarity protein CDC42 🧵⬇️
In our new @jcellsci.bsky.social paper, we report potent transcriptional adaptation by cytotoxic T lymphocytes (CTLs) in response to CRISPR/Cas9-mediated deletion of the important polarity protein CDC42 🧵⬇️
August 4, 2025 at 7:31 PM
Sometimes, knocking out a gene isn't a good way to figure out the function of that gene ...
In our new @jcellsci.bsky.social paper, we report potent transcriptional adaptation by cytotoxic T lymphocytes (CTLs) in response to CRISPR/Cas9-mediated deletion of the important polarity protein CDC42 🧵⬇️
In our new @jcellsci.bsky.social paper, we report potent transcriptional adaptation by cytotoxic T lymphocytes (CTLs) in response to CRISPR/Cas9-mediated deletion of the important polarity protein CDC42 🧵⬇️
As promised at my seminar at NCBS, here is the video showing what happens to the centrosome in a “confused T cell” that is contacting two targets with equal signals.
January 17, 2025 at 10:34 AM
As promised at my seminar at NCBS, here is the video showing what happens to the centrosome in a “confused T cell” that is contacting two targets with equal signals.
Welcome to the dynamic world of T cells!
January 8, 2025 at 9:59 AM
Welcome to the dynamic world of T cells!