Sarah Rice
@grainofscience.bsky.social
🇪🇺 Genetics and Epigenetics
Osteoarthritis Researcher 🎩
Versus Arthritis Career Development Fellow.
Newcastle University
research.ncl.ac.uk/ricelab
Osteoarthritis Researcher 🎩
Versus Arthritis Career Development Fellow.
Newcastle University
research.ncl.ac.uk/ricelab
The Rice Lab is moving! From January we will be based at the University of Manchester @manchester.ac.uk within the @arthritisuk.bsky.social Centre for Genetics and Genomics. Really excited about our new environment and our future research. I will be advertising PDRA and Tech posts in the New Year 🥳
October 23, 2025 at 11:27 AM
The Rice Lab is moving! From January we will be based at the University of Manchester @manchester.ac.uk within the @arthritisuk.bsky.social Centre for Genetics and Genomics. Really excited about our new environment and our future research. I will be advertising PDRA and Tech posts in the New Year 🥳
I am shocked by the belief that it is ok to be rude in manuscript reviews. Constructive criticism & challenging drawn conclusions is integral to peer review, but journal editors need to speak out and tell reviewers when their comments are unacceptable. We're better than this.
August 4, 2025 at 12:02 PM
I am shocked by the belief that it is ok to be rude in manuscript reviews. Constructive criticism & challenging drawn conclusions is integral to peer review, but journal editors need to speak out and tell reviewers when their comments are unacceptable. We're better than this.
Reposted by Sarah Rice
Absolutely delighted to share the labs latest work. We identify and characterise two pathways for D-ribulose utilisation in pathogenic EHEC and Citrobacter.
Convergent evolution of distinct D-ribulose utilisation pathways in attaching and effacing pathogens - Nature Communications
Cottam et al. identify distinct pathways for D-ribulose utilisation in pathogenic Escherichia coli and Citrobacter rodentium, providing mechanistic details and suggesting convergent evolution towards ...
www.nature.com
July 30, 2025 at 9:24 AM
Absolutely delighted to share the labs latest work. We identify and characterise two pathways for D-ribulose utilisation in pathogenic EHEC and Citrobacter.
Reposted by Sarah Rice
In his memory, Western has opened an equity-based graduate scholarship. Please consider supporting his final initiative if you are able: www.westernconnect.ca/beier ; thank you for all the time you spent and laughs you shared with him. We love and miss him so much already. - The Beiers
July 24, 2025 at 3:09 PM
In his memory, Western has opened an equity-based graduate scholarship. Please consider supporting his final initiative if you are able: www.westernconnect.ca/beier ; thank you for all the time you spent and laughs you shared with him. We love and miss him so much already. - The Beiers
Reposted by Sarah Rice
Hi all. Frank passed peacefully with the love of his family on July 18, 2025 in London, ON. He was a wonderful human being who shared much of his life with you. We could not have asked for a better father, grandfather, friend, colleague, or mentor. 1/
July 24, 2025 at 3:06 PM
Hi all. Frank passed peacefully with the love of his family on July 18, 2025 in London, ON. He was a wonderful human being who shared much of his life with you. We could not have asked for a better father, grandfather, friend, colleague, or mentor. 1/
Just when you thought all had gone quiet on the COLGALT2 front- get ready to hear more! Delighted that @hammofish.bsky.social and I have been awarded a four year grant from MRC @ukri.org to study the role of this enzyme in the skeleton. Will be advertising PDRA and RA posts in due course! #orthosky
July 15, 2025 at 5:17 PM
Just when you thought all had gone quiet on the COLGALT2 front- get ready to hear more! Delighted that @hammofish.bsky.social and I have been awarded a four year grant from MRC @ukri.org to study the role of this enzyme in the skeleton. Will be advertising PDRA and RA posts in due course! #orthosky
Reposted by Sarah Rice
New from The Strain Team:
🎊 Springer Nature Discovers MDPI 🎊
Springer Nature has spawned a copycat journal series called "Discover" mimicking #MDPI journal titles and citation behaviours. We even made a browser game to prove it (see 🔗).
Gross! 😀 1/n
#ResearchIntegrity #SciPub #AcademicSky
🎊 Springer Nature Discovers MDPI 🎊
Springer Nature has spawned a copycat journal series called "Discover" mimicking #MDPI journal titles and citation behaviours. We even made a browser game to prove it (see 🔗).
Gross! 😀 1/n
#ResearchIntegrity #SciPub #AcademicSky
Spinger Nature Discovers MDPI – The Strain on Scientific Publishing
Home page for the paper ‘The Strain on Scientific Publishing’ by Mark A Hanson, Dan Brockington, Paolo Crosetto and Pablo Gomez Barreiro
the-strain-on-scientific-publishing.github.io
June 10, 2025 at 5:49 AM
New from The Strain Team:
🎊 Springer Nature Discovers MDPI 🎊
Springer Nature has spawned a copycat journal series called "Discover" mimicking #MDPI journal titles and citation behaviours. We even made a browser game to prove it (see 🔗).
Gross! 😀 1/n
#ResearchIntegrity #SciPub #AcademicSky
🎊 Springer Nature Discovers MDPI 🎊
Springer Nature has spawned a copycat journal series called "Discover" mimicking #MDPI journal titles and citation behaviours. We even made a browser game to prove it (see 🔗).
Gross! 😀 1/n
#ResearchIntegrity #SciPub #AcademicSky
Reposted by Sarah Rice
Today, I take the reigns as Chair, Human Evolutionary Biology, Harvard. Big thankyou to Dan Lieberman outgoing Chair & Joe Henrich, previous Chair. They did tremendous jobs advancing HEB's intellectual/academic vibrancy. I'll work hard for all students, postdocs & faculty in this changing landscape
May 29, 2025 at 1:23 PM
Today, I take the reigns as Chair, Human Evolutionary Biology, Harvard. Big thankyou to Dan Lieberman outgoing Chair & Joe Henrich, previous Chair. They did tremendous jobs advancing HEB's intellectual/academic vibrancy. I'll work hard for all students, postdocs & faculty in this changing landscape
Reposted by Sarah Rice
We are responding legally to our President’s illegal acts! All should do the same
www.nytimes.com/2025/05/23/u...
www.nytimes.com/2025/05/23/u...
Harvard Sues Trump Administration Over Move to Bar International Students
www.nytimes.com
May 23, 2025 at 12:50 PM
We are responding legally to our President’s illegal acts! All should do the same
www.nytimes.com/2025/05/23/u...
www.nytimes.com/2025/05/23/u...
Reposted by Sarah Rice
1) Despite the chaos, I am very pleased to present the terrific research conducted by my post-doc @clarissacoveney.bsky.social. acrjournals.onlinelibrary.wiley.com/doi/10.1002/...
Complex regulatory interactions at GDF5 shape joint morphology and osteoarthritis disease risk
Objectives To reveal causal level osteoarthritis (OA) disease biology by targeting regulatory interactions at GDF5. Methods By investigating different GDF5 regulatory regions (R2, R3-5, R7-R9, R18...
acrjournals.onlinelibrary.wiley.com
May 21, 2025 at 2:11 PM
1) Despite the chaos, I am very pleased to present the terrific research conducted by my post-doc @clarissacoveney.bsky.social. acrjournals.onlinelibrary.wiley.com/doi/10.1002/...
Reposted by Sarah Rice
Does anyone have a Col156 plasmid (small, high-copy, not co-integrated on an F) handy they’d be willing to share? 🧪
May 20, 2025 at 8:17 PM
Does anyone have a Col156 plasmid (small, high-copy, not co-integrated on an F) handy they’d be willing to share? 🧪
It doesn't matter how many times I try to grasp this, I'll never know what you mean when you talk about "top down" or "bottom up" approaches. So please find another way to convey to me whatever point you need to make. This is a hill I'll die on.
a woman wearing glasses is drinking from a mason jar and saying `` girls , bottoms up ! ''
ALT: a woman wearing glasses is drinking from a mason jar and saying `` girls , bottoms up ! ''
media.tenor.com
May 8, 2025 at 1:16 PM
It doesn't matter how many times I try to grasp this, I'll never know what you mean when you talk about "top down" or "bottom up" approaches. So please find another way to convey to me whatever point you need to make. This is a hill I'll die on.
Reposted by Sarah Rice
Remember when you first learned about genetics at school? All those fascinating examples of human traits that are each apparently determined by just a single gene? Time to check in on some of your favourites to see how they’re doing. 🧬🧵🧪 1/n
May 2, 2025 at 2:50 PM
Remember when you first learned about genetics at school? All those fascinating examples of human traits that are each apparently determined by just a single gene? Time to check in on some of your favourites to see how they’re doing. 🧬🧵🧪 1/n
For the 3rd #EpigeneticsOA workshop, 77 attendees united to discuss progress and potential of our field. Delighted to see the meeting report in print! Whether you made it, or missed out, catch up w/ the outcomes here --> bit.ly/42YeWnT #orthosky @oacjournal.bsky.social @versusarthritis.bsky.social
From mechanism to medicine: the progress and potential of epigenetics in osteoarthritis
Osteoarthritis (OA) is a chronic, degenerative disease of the articular joints. The disease presents an enormous clinical and economic burden globally…
bit.ly
May 3, 2025 at 8:35 AM
For the 3rd #EpigeneticsOA workshop, 77 attendees united to discuss progress and potential of our field. Delighted to see the meeting report in print! Whether you made it, or missed out, catch up w/ the outcomes here --> bit.ly/42YeWnT #orthosky @oacjournal.bsky.social @versusarthritis.bsky.social
Reposted by Sarah Rice
Congrats to our very own Kevin Burt for scoring among the highest-rated abstracts by early career investigators at #OARSI2025.
April 24, 2025 at 8:27 AM
Congrats to our very own Kevin Burt for scoring among the highest-rated abstracts by early career investigators at #OARSI2025.
Reposted by Sarah Rice
So nice to be back home in Korea and excited to be at #OARSI2025! Stop by poster #595 where I’m presenting on chromatin accessibility QTLs in resting/FNF-stimulated primary human chondrocytes. I’ve been integrating eQTL, sQTL, and Hi-C data to better understand gene regulation in osteoarthritis.
April 25, 2025 at 2:37 PM
So nice to be back home in Korea and excited to be at #OARSI2025! Stop by poster #595 where I’m presenting on chromatin accessibility QTLs in resting/FNF-stimulated primary human chondrocytes. I’ve been integrating eQTL, sQTL, and Hi-C data to better understand gene regulation in osteoarthritis.
Hanging with my symbiont @curlygeneticist.bsky.social #OARSI2025
April 25, 2025 at 3:07 PM
Hanging with my symbiont @curlygeneticist.bsky.social #OARSI2025
I'm honoured to be in Korea this week to collect my Rising Star Award at #OARSI2025 Thank you so much to
OARSI for this award, and @beierlab.bsky.social for generously nominating me. Having a wonderful time all round 🇰🇷
OARSI for this award, and @beierlab.bsky.social for generously nominating me. Having a wonderful time all round 🇰🇷
April 25, 2025 at 6:21 AM
I'm honoured to be in Korea this week to collect my Rising Star Award at #OARSI2025 Thank you so much to
OARSI for this award, and @beierlab.bsky.social for generously nominating me. Having a wonderful time all round 🇰🇷
OARSI for this award, and @beierlab.bsky.social for generously nominating me. Having a wonderful time all round 🇰🇷
After a few days exploring Seoul, I’m exited to be in sunny Incheon for #OARSI2025
April 24, 2025 at 7:19 AM
After a few days exploring Seoul, I’m exited to be in sunny Incheon for #OARSI2025
Excited to be in South Korea for #OARSI2025 I’ve landed a few days early and I’m making the most of it!
April 21, 2025 at 2:06 PM
Excited to be in South Korea for #OARSI2025 I’ve landed a few days early and I’m making the most of it!
Congratulations to @fornerislab.bsky.social on the publication of their work to characterise COLGALT1 this week in @natcomms.nature.com. This is a really beautiful study and it is great to see it in print! 👏🏼
Excited to share our new Nature Communications paper describing the molecular structure and the biochemical characterization of human #collagen #galactosyltransferase GLT25D1/COLGALT1 #glycotime www.nature.com/articles/s41...
Molecular structure and enzymatic mechanism of the human collagen hydroxylysine galactosyltransferase GLT25D1/COLGALT1 - Nature Communications
Hydroxylysine galactosylation is essential for collagen maturation. This work reveals the molecular structure of human GLT25D1, its catalytic residues, and a noncatalytic structural domain stabilized ...
www.nature.com
April 18, 2025 at 8:40 AM
Congratulations to @fornerislab.bsky.social on the publication of their work to characterise COLGALT1 this week in @natcomms.nature.com. This is a really beautiful study and it is great to see it in print! 👏🏼
Well done to my PhD Student Abby Brumwell on delivering a great talk to a full room at the @mosmedcdt.bsky.social annual conference this afternoon! #ProudPI @cgm-newcastle.bsky.social
April 15, 2025 at 3:53 PM
Well done to my PhD Student Abby Brumwell on delivering a great talk to a full room at the @mosmedcdt.bsky.social annual conference this afternoon! #ProudPI @cgm-newcastle.bsky.social
Reposted by Sarah Rice
New preprint on 3D heterochromatin architecture in human cells! Great collab with @sergiocruzleon.bsky.social & @johannesbetz.bsky.social from @hummerlab.bsky.social, @marinalusic.bsky.social & the Turoňová lab. Many thanks to my supervisor @becklab.bsky.social. bioRxiv: tinyurl.com/3a74uanv 🧵👇
April 11, 2025 at 9:04 AM
New preprint on 3D heterochromatin architecture in human cells! Great collab with @sergiocruzleon.bsky.social & @johannesbetz.bsky.social from @hummerlab.bsky.social, @marinalusic.bsky.social & the Turoňová lab. Many thanks to my supervisor @becklab.bsky.social. bioRxiv: tinyurl.com/3a74uanv 🧵👇
Our Editorial is now online! Here, we discuss recent advancements and pertinent challenges in applying modern 'omics technologies to MSK tissues. This introduces our @oacjournal.bsky.social special edition. Still ~4 weeks left if you have a paper in the works! www.sciencedirect.com/science/arti...
A timely assessment of the state of transcriptomic and epigenomic profiling in OA: Opportunities for advancements
www.sciencedirect.com
April 5, 2025 at 11:50 AM
Our Editorial is now online! Here, we discuss recent advancements and pertinent challenges in applying modern 'omics technologies to MSK tissues. This introduces our @oacjournal.bsky.social special edition. Still ~4 weeks left if you have a paper in the works! www.sciencedirect.com/science/arti...
The Rice Lab is going to Korea! If you are interested in our latest research on the DNA methylome and proteome of primary human skeletal tissues, stop by Abby's poster and catch our talks in Sunday's multiomics session.
@mosmedcdt.bsky.social
@oarsi-eci.bsky.social
@versusarthritis.bsky.social
@mosmedcdt.bsky.social
@oarsi-eci.bsky.social
@versusarthritis.bsky.social
April 4, 2025 at 8:37 AM
The Rice Lab is going to Korea! If you are interested in our latest research on the DNA methylome and proteome of primary human skeletal tissues, stop by Abby's poster and catch our talks in Sunday's multiomics session.
@mosmedcdt.bsky.social
@oarsi-eci.bsky.social
@versusarthritis.bsky.social
@mosmedcdt.bsky.social
@oarsi-eci.bsky.social
@versusarthritis.bsky.social