Goutham Atla
@gouthamatla.bsky.social
Genetics and Epigenetics of Cardio Metabolic Traits. Oxford.
Research collaborator @ Imperial College London, visiting scientist @ Broad Institute.
Research collaborator @ Imperial College London, visiting scientist @ Broad Institute.
Reposted by Goutham Atla
An HNF1A-A1CF transcription splicing axis regulates insulin secretion, and breaks down in T2D.
Amazing work led by Edgar Bernardo + Matias de Vas + major contributions from Diego Balboa, Silvia Bonas, Mirabai Cuenca, Fanny Mollandin, Merce Planas, Miquel Torrent, MA Maestro and many others
Amazing work led by Edgar Bernardo + Matias de Vas + major contributions from Diego Balboa, Silvia Bonas, Mirabai Cuenca, Fanny Mollandin, Merce Planas, Miquel Torrent, MA Maestro and many others
HNF1A and A1CF coordinate a beta cell transcription-splicing axis that is disrupted in type 2 diabetes
Bernardo et al. uncover a transcription-splicing regulatory axis driven by HNF1A and
A1CF in pancreatic β cells. Targeted perturbations, single-cell studies, and human
genetic evidence demonstrate tha...
www.cell.com
August 6, 2025 at 8:14 PM
An HNF1A-A1CF transcription splicing axis regulates insulin secretion, and breaks down in T2D.
Amazing work led by Edgar Bernardo + Matias de Vas + major contributions from Diego Balboa, Silvia Bonas, Mirabai Cuenca, Fanny Mollandin, Merce Planas, Miquel Torrent, MA Maestro and many others
Amazing work led by Edgar Bernardo + Matias de Vas + major contributions from Diego Balboa, Silvia Bonas, Mirabai Cuenca, Fanny Mollandin, Merce Planas, Miquel Torrent, MA Maestro and many others
Reposted by Goutham Atla
Happy to announce that HPAP now has some 180 human pancreatic analyzed by highly multiplexed CODEX analysis. Thanks to Dr. Powers and the whole HPAP team! Here is the link to the experiment data download page: hpap.pmacs.upenn.edu/explore/down...
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🧪
hpap.pmacs.upenn.edu
June 30, 2025 at 7:21 PM
Happy to announce that HPAP now has some 180 human pancreatic analyzed by highly multiplexed CODEX analysis. Thanks to Dr. Powers and the whole HPAP team! Here is the link to the experiment data download page: hpap.pmacs.upenn.edu/explore/down...
🧪
🧪
Reposted by Goutham Atla
@saramostafavi.bsky.social (@Genentech) & I (@Stanford) r excited to announce co-advised postdoc positions for candidates with deep expertise in ML for bio (especially sequence to function models, causal perturbational models & single cell models). See details below. Pls RT 1/
June 19, 2025 at 8:55 PM
@saramostafavi.bsky.social (@Genentech) & I (@Stanford) r excited to announce co-advised postdoc positions for candidates with deep expertise in ML for bio (especially sequence to function models, causal perturbational models & single cell models). See details below. Pls RT 1/
Reposted by Goutham Atla
our work on the molecular differences between transcription factor isoforms is out now in Molecular Cell!
key point: 2/3rds of TF isos differ in properties like DNA binding & transcriptional activity
many are "negative regulators" & misexpressed in cancer
www.sciencedirect.com/science/arti...
key point: 2/3rds of TF isos differ in properties like DNA binding & transcriptional activity
many are "negative regulators" & misexpressed in cancer
www.sciencedirect.com/science/arti...
March 26, 2025 at 5:11 PM
our work on the molecular differences between transcription factor isoforms is out now in Molecular Cell!
key point: 2/3rds of TF isos differ in properties like DNA binding & transcriptional activity
many are "negative regulators" & misexpressed in cancer
www.sciencedirect.com/science/arti...
key point: 2/3rds of TF isos differ in properties like DNA binding & transcriptional activity
many are "negative regulators" & misexpressed in cancer
www.sciencedirect.com/science/arti...
Reposted by Goutham Atla
Excited to share this position for a computational biologist to work on Translational Diabetes Genomics in Diverse populations. Great opportunities to learn and grow and expand your career ! Please share!
broadinstitute.avature.net/en_US/career...
broadinstitute.avature.net/en_US/career...
Computational Associate II- Translational Diabetes Genomics In Diverse Populations
Job DescriptionApply your computational and mathematical skills to solving the hardest problems in big-data genomics and have a wide impact on science and clinical practice, including diabetes and...
broadinstitute.avature.net
March 10, 2025 at 2:02 AM
Excited to share this position for a computational biologist to work on Translational Diabetes Genomics in Diverse populations. Great opportunities to learn and grow and expand your career ! Please share!
broadinstitute.avature.net/en_US/career...
broadinstitute.avature.net/en_US/career...
Reposted by Goutham Atla
Still time to apply!
Applications from US welcome – four years can feel longer or shorter depending on where you are 😉
Applications from US welcome – four years can feel longer or shorter depending on where you are 😉
📣 Hiring, please forward widely!!
Two postdoc openings to work on genomics of diabetes
1. Computational regulatory genomics/statistical genetics.
2. Experimental cell-based modeling
DM if interested
@crg.eu
shorturl.at/O3wMi
shorturl.at/ieyZy
Two postdoc openings to work on genomics of diabetes
1. Computational regulatory genomics/statistical genetics.
2. Experimental cell-based modeling
DM if interested
@crg.eu
shorturl.at/O3wMi
shorturl.at/ieyZy
Postdoctoral scientist, gene regulatory mechanisms and diabetes | CRG Online Recruitment Portal
The Centre for Genomic Regulation (CRG) is an international biomedical research institute of excellence, based in Barcelona, Spain, with more than 400 scientists from 44 countries. The CRG is composed by an interdisciplinary, motivated and creative scientific team which is supported both by a flexible and efficient administration and by high-end and innovative technologies.
shorturl.at
February 2, 2025 at 8:18 PM
Still time to apply!
Applications from US welcome – four years can feel longer or shorter depending on where you are 😉
Applications from US welcome – four years can feel longer or shorter depending on where you are 😉
An amazing podcast discussing about the genetic nurture, polygenic burden in rare diseases, probably applicable to cardiometabolic traits podcasts.apple.com/gb/podcast/t...
EP 169: Common variants in rare neurological diseases with Hilary Martin of the Wellcome Sanger Institute
Podcast Episode · The Genetics Podcast · 09/01/2025 · 46m
podcasts.apple.com
January 21, 2025 at 6:50 PM
An amazing podcast discussing about the genetic nurture, polygenic burden in rare diseases, probably applicable to cardiometabolic traits podcasts.apple.com/gb/podcast/t...