Gopinath Chattopadhyay
@gopinath21.bsky.social
Postdoc @UZH_Science in the Wagner lab. Into protein evolution, gene regulation & microbial adaptation. He/him.
Here we mapped ~250,000 variants of a classic regulatory element in E. coli. Even this tiny 9-bp sequence encodes a rugged, environment-sensitive fitness landscape.
It shows how gene regulation can constrain—or enable—evolution, depending on the context.
It shows how gene regulation can constrain—or enable—evolution, depending on the context.
July 28, 2025 at 12:59 PM
Here we mapped ~250,000 variants of a classic regulatory element in E. coli. Even this tiny 9-bp sequence encodes a rugged, environment-sensitive fitness landscape.
It shows how gene regulation can constrain—or enable—evolution, depending on the context.
It shows how gene regulation can constrain—or enable—evolution, depending on the context.