Gopinath Chattopadhyay
@gopinath21.bsky.social
Postdoc @UZH_Science in the Wagner lab. Into protein evolution, gene regulation & microbial adaptation. He/him.
Reposted by Gopinath Chattopadhyay
Excited / nervous to share the “magnum opus” of my postdoc in Andreas Wagner’s lab!
"De-novo promoters emerge more readily from random DNA than from genomic DNA"
This project is the accumulation of 4 years of work, and lays the foundation for my future group. In short, we… (1/4)
"De-novo promoters emerge more readily from random DNA than from genomic DNA"
This project is the accumulation of 4 years of work, and lays the foundation for my future group. In short, we… (1/4)
De-novo promoters emerge more readily from random DNA than from genomic DNA
Promoters are DNA sequences that help to initiate transcription. Point mutations can create de-novo promoters, which can consequently transcribe inactive genes or create novel transcripts. We know lit...
www.biorxiv.org
August 28, 2025 at 6:37 AM
Excited / nervous to share the “magnum opus” of my postdoc in Andreas Wagner’s lab!
"De-novo promoters emerge more readily from random DNA than from genomic DNA"
This project is the accumulation of 4 years of work, and lays the foundation for my future group. In short, we… (1/4)
"De-novo promoters emerge more readily from random DNA than from genomic DNA"
This project is the accumulation of 4 years of work, and lays the foundation for my future group. In short, we… (1/4)
🚨 New preprint from the Andreas Wagner lab
lab at University of Zurich, with Andrei Papkou:
🧬 "The fitness landscape of the E. coli lac operator is highly rugged in two environments"
🔗 biorxiv.org/content/10.1...
🧡 Powered by URPP Evolution in Action
lab at University of Zurich, with Andrei Papkou:
🧬 "The fitness landscape of the E. coli lac operator is highly rugged in two environments"
🔗 biorxiv.org/content/10.1...
🧡 Powered by URPP Evolution in Action
The fitness landscape of the E.coli lac operator is highly rugged in two different environments
We know little about the fitness landscapes of bacterial operators, regulatory DNA elements that are crucial to regulate metabolic genes like those of the lac operon for lactose utilization. For examp...
biorxiv.org
July 28, 2025 at 12:59 PM
🚨 New preprint from the Andreas Wagner lab
lab at University of Zurich, with Andrei Papkou:
🧬 "The fitness landscape of the E. coli lac operator is highly rugged in two environments"
🔗 biorxiv.org/content/10.1...
🧡 Powered by URPP Evolution in Action
lab at University of Zurich, with Andrei Papkou:
🧬 "The fitness landscape of the E. coli lac operator is highly rugged in two environments"
🔗 biorxiv.org/content/10.1...
🧡 Powered by URPP Evolution in Action