@gomeslabo.bsky.social
Happy to collaborate o this work. Nice to see the role of bin1 in alzheimer
🧠 What if Alzheimer’s risk starts at the synapse?
In our new study led by Mariana Barata, we show that BIN1, a key AD risk gene, regulates inhibitory synapses—loss of BIN1 → hyperexcitability before Aβ.
www.cell.com/cell-reports...
In our new study led by Mariana Barata, we show that BIN1, a key AD risk gene, regulates inhibitory synapses—loss of BIN1 → hyperexcitability before Aβ.
www.cell.com/cell-reports...
Alzheimer’s genetic risk factor Bin1 controls synapse vesicle exo-endocytosis in inhibitory synapses
Barata et al. show that the Alzheimer’s risk gene BIN1 is critical for the stability
of inhibitory synapses. BIN1 deficiency accelerates the synaptic vesicle endocytic
cycle, leading to synapse loss a...
www.cell.com
July 20, 2025 at 1:48 PM
Happy to collaborate o this work. Nice to see the role of bin1 in alzheimer
Reposted
Our latest: how to generate the notochord
"Timely TGFβ signalling inhibition induces notochord"
A thread:
www.nature.com/articles/s41...
"Timely TGFβ signalling inhibition induces notochord"
A thread:
www.nature.com/articles/s41...
Timely TGFβ signalling inhibition induces notochord - Nature
Through analysis of developing chick embryos and in vitro differentiation of embryonic stem cells, a study develops a method to generate a model of the human trunk with a notochord.
www.nature.com
December 19, 2024 at 8:52 AM
Our latest: how to generate the notochord
"Timely TGFβ signalling inhibition induces notochord"
A thread:
www.nature.com/articles/s41...
"Timely TGFβ signalling inhibition induces notochord"
A thread:
www.nature.com/articles/s41...
Stretching muscle with Lego water recycling Pumpy parts from @henriqueslab.bsky.social
December 19, 2024 at 3:07 PM
Stretching muscle with Lego water recycling Pumpy parts from @henriqueslab.bsky.social