George Birchenough
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gobletcellguy.bsky.social
George Birchenough
@gobletcellguy.bsky.social
Updates from the Birchenough Lab, one of the Mucin Biology Groups based at the University of Gothenburg. All things goblet cell, mucus and mucin. Check us out:
www.birchenoughlab.org
https://www.medkem.gu.se/mucinbiology/
Here is black mirror's creator Charlie Brooker guest hosting a long running British satirical news show the same week that Trump was first elected, enjoy 🫠
youtu.be/LZIDgYEvDn4?...
Charlie Brooker HIGNFY Intro - 11/11/2016
YouTube video by BluebackHotrod
youtu.be
April 19, 2025 at 9:50 PM
Fair point, but I think there are issues with the paper itself - missing methods regarding enzymatic treatment of colonic mucus, amongst others.
February 23, 2025 at 8:08 AM
I think it's safe to say that the reviewers were not into glycobiology, which is a shame because it's the mechanistic basis of the paper.. 🫠
February 22, 2025 at 11:48 AM
Here's another for you, also a Nature family journal funnily enough 😅:
www.nature.com/articles/s41...
February 21, 2025 at 2:29 PM
This was ultimately traced back to significant flagellar upreg in the FimH KO bugs, but I think that an important moral of the story here is that for highly motile bugs, the mucus "barrier" really isn't 🫣
February 17, 2025 at 3:43 PM
Interestingly loss of the #FimH adhesin disrupted UPEC mucosal associations in vivo, but weirdly dramatically increased its capacity to penetrate the mucus barrier ex vivo
February 17, 2025 at 3:40 PM
Huh, not sure why that link didn't work... anyway it's pinned to my profile 😆
February 17, 2025 at 9:13 AM