Hiren Joshi
@glyco.me
Glycobioinfonaut, Associate Professor at the Copenhagen Center for Glycomics, University of Copenhagen. @hirenj.11 on Signal
Peter Panum was a Dane working in Germany, and the amazing brutalist building we were based in (and are now next to) is named after him.
November 12, 2025 at 7:08 AM
Peter Panum was a Dane working in Germany, and the amazing brutalist building we were based in (and are now next to) is named after him.
Questionably fun fact: The study of endotoxin in modern age was kicked off by Peter Panum (studying putrid fluids). He had also done work on albumen, releasing “something” with dilute acid hydrolysis. Eichwald in 1865 did that same reaction on mucin, arguably starting the study of glycoproteins.
November 12, 2025 at 7:08 AM
Questionably fun fact: The study of endotoxin in modern age was kicked off by Peter Panum (studying putrid fluids). He had also done work on albumen, releasing “something” with dilute acid hydrolysis. Eichwald in 1865 did that same reaction on mucin, arguably starting the study of glycoproteins.
Pretty low-effort example of plagiarism here.
October 25, 2025 at 11:54 AM
Pretty low-effort example of plagiarism here.
Sad, but probably inevitable news from Vodafone AU. I have been sitting on an ancient mobile phone plan for the past 25 years, with no minimum cost for infrequent usage, and they’re finally removing the plan. Are there any reputable places to port Australian mobile numbers to for e.g., VOIP?
August 8, 2025 at 8:49 AM
Sad, but probably inevitable news from Vodafone AU. I have been sitting on an ancient mobile phone plan for the past 25 years, with no minimum cost for infrequent usage, and they’re finally removing the plan. Are there any reputable places to port Australian mobile numbers to for e.g., VOIP?
Kim Jong-un inspects the latest in North Korean shark tank technology.
June 26, 2025 at 1:51 PM
Kim Jong-un inspects the latest in North Korean shark tank technology.
This Lorenz Oken guy might just be on to something. The article mixes slime and mucus interchangeably, but it is a good read about the relative rarity of complex life. www.asimov.press/p/slime
June 21, 2025 at 2:14 PM
This Lorenz Oken guy might just be on to something. The article mixes slime and mucus interchangeably, but it is a good read about the relative rarity of complex life. www.asimov.press/p/slime
CCG (incl @manno.se and @xylobecs.bsky.social) representing at the half marathon across the Øresund bridge today. Lovely weather for it!
June 15, 2025 at 5:09 PM
CCG (incl @manno.se and @xylobecs.bsky.social) representing at the half marathon across the Øresund bridge today. Lovely weather for it!
Well, it turns out that you can actually make PyMOL do quite a lot of stuff. Here's the full workflow, integrating the amazing ReGlyco into PyMOL to re-glycosylate the LDLA linker. There's some serious magic needed to get it running as fast as it is within PyMOL. @elisafadda.bsky.social
June 10, 2025 at 10:05 PM
Well, it turns out that you can actually make PyMOL do quite a lot of stuff. Here's the full workflow, integrating the amazing ReGlyco into PyMOL to re-glycosylate the LDLA linker. There's some serious magic needed to get it running as fast as it is within PyMOL. @elisafadda.bsky.social
A little bit of glycan binding structure for your Tuesday.
May 6, 2025 at 10:33 AM
A little bit of glycan binding structure for your Tuesday.
I have this script I use to munge citations in word docs, that spelunks into the XML and creates Zotero/Mendeley compatible field codes. I figured it couldn’t be that hard to get it working for EndNote. It was. Even Gemini told me not to, which made me even more determined. Now it works.
April 23, 2025 at 7:45 PM
I have this script I use to munge citations in word docs, that spelunks into the XML and creates Zotero/Mendeley compatible field codes. I figured it couldn’t be that hard to get it working for EndNote. It was. Even Gemini told me not to, which made me even more determined. Now it works.
The ream is defined as 20 quires of 25 sheets. And why…?
April 9, 2025 at 3:17 PM
The ream is defined as 20 quires of 25 sheets. And why…?
I mean, it’s one ream of paper, Fiona. What would it cost, $10?
April 9, 2025 at 3:26 AM
I mean, it’s one ream of paper, Fiona. What would it cost, $10?
"Your scientists were so preoccupied with whether or not they could that they didn't stop to think if they should" @elisafadda.bsky.social , you know we could make an awesome plugin.
April 1, 2025 at 9:02 PM
"Your scientists were so preoccupied with whether or not they could that they didn't stop to think if they should" @elisafadda.bsky.social , you know we could make an awesome plugin.
Yet still a vast improvement over the old model!
March 30, 2025 at 11:06 AM
Yet still a vast improvement over the old model!
I’m as against the AI slop it’s all too easy to make, but it’s still pretty impressive tech. I always test the latest stuff on my standard prompt - riffing on Harrison Ford in “Extraordinary Measures”.
March 30, 2025 at 9:51 AM
I’m as against the AI slop it’s all too easy to make, but it’s still pretty impressive tech. I always test the latest stuff on my standard prompt - riffing on Harrison Ford in “Extraordinary Measures”.
March 21, 2025 at 5:49 PM
Do we need another isoform expressed? Pretty common to have two isoforms of ST8SIA expressed in a cell. Do most of the other cells also have a dormant capacity to make PolySia (activated by having whatever this other factor is?)
January 16, 2025 at 9:06 PM
Do we need another isoform expressed? Pretty common to have two isoforms of ST8SIA expressed in a cell. Do most of the other cells also have a dormant capacity to make PolySia (activated by having whatever this other factor is?)
My daughter is learning the art of text messaging, in a bilingual manner. Sometimes messages don’t quite come across in the way she expected.
January 15, 2025 at 7:13 AM
My daughter is learning the art of text messaging, in a bilingual manner. Sometimes messages don’t quite come across in the way she expected.
Wait, is that WINE as in WINE Is Not an Emulator, i.e., the windows compatibility layer on Linux? If so..
December 20, 2024 at 6:03 AM
Wait, is that WINE as in WINE Is Not an Emulator, i.e., the windows compatibility layer on Linux? If so..
Already there! You can go to the list, and click on pin, fiddle around a bit, and get your BlueSky feed to default to glyco all the time, because we all know that's the only thing worth social media-ing about!
November 19, 2024 at 2:15 PM
Already there! You can go to the list, and click on pin, fiddle around a bit, and get your BlueSky feed to default to glyco all the time, because we all know that's the only thing worth social media-ing about!
It kind of just flops the sugars on the structure. We know α-Man doesn’t really change secondary structure on β-strands/sheets (e.g., cadherins). So I guess that’s consistent. Otherwise 🤷🏽♂️ ? We might be able to see this using CryoEM/whatever.
August 22, 2024 at 4:24 PM
It kind of just flops the sugars on the structure. We know α-Man doesn’t really change secondary structure on β-strands/sheets (e.g., cadherins). So I guess that’s consistent. Otherwise 🤷🏽♂️ ? We might be able to see this using CryoEM/whatever.
If you’re interested in putting glycoproteins into #alphafold3 but don’t know which glycans to put in, I have a tool for you. You can either search for proteins, and it will pre-populate a JSON job file for you, or you can draw biologically plausible glycans, and get the AF code for them.
May 13, 2024 at 4:13 PM
If you’re interested in putting glycoproteins into #alphafold3 but don’t know which glycans to put in, I have a tool for you. You can either search for proteins, and it will pre-populate a JSON job file for you, or you can draw biologically plausible glycans, and get the AF code for them.
October 11, 2023 at 5:49 PM
I think I need to spend some time digesting exactly what is going on here.
October 10, 2023 at 12:21 PM
I think I need to spend some time digesting exactly what is going on here.