Global Pneumococcal Sequencing Project
globalpneumoseq.bsky.social
Global Pneumococcal Sequencing Project
@globalpneumoseq.bsky.social
GPS, the Global Pneumococcal Sequencing project funded by The Bill and Melinda Gates Foundation is sequencing ~50,000 pneumococci to monitor global vaccine implementation and impact.
https://www.pneumogen.net/gps/
Here’s how the pipeline works 👇
September 24, 2025 at 1:02 PM
Potential new pbp substitutions that link to beta-lactam resistance in S pneumoniae
September 22, 2025 at 11:48 AM
By linking their shifts in the phenotypic map above with the amino acid changes in PBP protein, we could pinpoint particular substitutions and its impact on resistance.
September 22, 2025 at 11:48 AM
Some pneumococcal lineages are more resistance to beta-lactams - coincides with our observations in the #GPS_project
September 22, 2025 at 11:48 AM
AMR cartography to show the MIC values of multiple antibiotics
September 22, 2025 at 11:48 AM
Last week in #Europneumo2025, the GPS core team presents

1) Database of 26k pneumococcal genomes @harryhung.bsky.social
2) Global population structure of serotype 12F @dralannah.bsky.social
3) SeroBA - WGS-based tool to detect 102 known pneumococcal serotypes @OliverLorenz
June 2, 2025 at 10:46 PM