Gilbert Han
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gilberthan.bsky.social
Gilbert Han
@gilberthan.bsky.social
Bioinformaticians. My pages : https://gilberthan1011.github.io
No one deserves to be treated like this.
Just want to note that the person who sequenced it and gave the go-ahead for Holmes to publish was Zhang Yongzhen, who’s since paid a pretty heavy price for it (not trying to take anything away from Holmes)
This Chinese virologist shared crucial Covid-19 data. Then his research hit hurdles | CNN
Scientist was lauded for his 2020 disclosure, but in the years since, people who know him say he has faced unprecedented roadblocks in his career in China.
www.cnn.com
January 11, 2025 at 4:27 AM
Reposted by Gilbert Han
EpiAgent: Foundation model for single-cell epigenomic data https://www.biorxiv.org/content/10.1101/2024.12.19.629312v1
December 22, 2024 at 2:47 AM
Reposted by Gilbert Han
I'm writing up a brief history of the tidyverse? What do you want to know about it? #rstats
November 25, 2024 at 3:24 PM
Reposted by Gilbert Han
The promised GitHub repository is live: github.com/cxli233/Colo...
November 25, 2024 at 4:30 AM
I recently developed an R package called linkSet, designed to handle promoter-enhancer interactions. I've just published a blog post shows how it can help process HiC and PC-HiC datasets. I would greatly appreciate any feedback from those who try it out.. gilberthan1011.github.io/blog/2024/wh...
Why we need LinkSet? | Gilbert Han
Introduction to the motivation of LinkSet
gilberthan1011.github.io
November 23, 2024 at 9:49 AM
Reposted by Gilbert Han
I am happy to share the link to video and pdf of 2nd lecture at College de France on biological information. I present & discuss general properties of Biological Codes (genetic, transcriptional, signalling and adhesion codes) dealing with balance btw diversity and specificity.

tinyurl.com/5dv39v4v
November 22, 2024 at 9:59 AM
Reposted by Gilbert Han
One enhancer can activate two endogenous genes simultaneously and across a TAD Boundary. Check out our new preprint.
www.biorxiv.org/content/10.1...
November 5, 2024 at 1:44 PM
Reposted by Gilbert Han
A stimulating workshop on the subject of Waddington Landscapes in Lyon last week, prompted me to compose some thoughts on dynamical landscapes, gene regulatory networks, and single cell transcriptomics

briscoelab.org/morphogenalia/
Briscoe Lab
Developmental Dynamics of Tissue Formation
briscoelab.org
November 12, 2024 at 12:21 PM
Reposted by Gilbert Han
A nice complement to @lpachter.bsky.social 's lab preprint www.biorxiv.org/content/10.1...
November 19, 2024 at 7:03 AM
Reposted by Gilbert Han
Hi Everyone! 👋 Allow me to introduce myself. I'm Kate. I'm a postdoc studying early mammalian development, mechanics, and reproductive aging. Check out one of my favorite developmental stages in a mouse embryo in this video:
November 14, 2024 at 1:09 AM
Reposted by Gilbert Han
For so many, there was a book - often read ~20yo - that had a very big influence on their next steps. Do you have a book story like that? Do tell!

My book was Crick's "Astonishing Hypothesis". I got to feature my 30yo tattered copy in a recent photo shoot.

www.thetransmitter.org/summer-readi...
November 18, 2024 at 12:00 PM
Reposted by Gilbert Han
(1/8) 🚀 Excited to share our findings on a large-scale ChIP-seq assay for 166 previously uncharacterized human transcription factors (TFs) and their roles in both regulatory regions, and more strikingly, the “dark matter” genome. 🌌 doi.org/10.1101/2024....
Extensive binding of uncharacterized human transcription factors to genomic dark matter
Most of the human genome is thought to be non-functional, and includes large segments often referred to as “dark matter” DNA. The genome also encodes hundreds of putative and poorly characterized tran...
doi.org
November 15, 2024 at 7:02 PM
Reposted by Gilbert Han
Here is the link to video of introduction course @cdf1530 on biological information. A historical perspective on evolution of representations of the genome, highlighting contributions of von Neumann, Jacob&Monod, Waddington, Alberch etc.
Video (french)+pdf (english):

tinyurl.com/y4k44cd4
November 16, 2024 at 9:53 AM
I've created a navigation website featuring the Bioinfomatics Bluesky packages I'm interested in, along with other resources. Please let me know if there's anything I should add. You can check it out here.
gilberthan1011.github.io/nav/#/?page=...
Bioinfo Explorer
Curated Bioinformatics Resources
gilberthan1011.github.io
November 15, 2024 at 1:01 PM