UCSC Genome Browser
@genomebrowser.bsky.social
The UCSC Genome Browser is a public, freely available, open-source web-based graphical viewer for displaying genome sequences and their annotations.
We are pleased to announce the hg38 SpliceAI Wildtype tracks. These tracks show the scores for the genome sequence itself, without variants, from predicted splice donor and splice acceptor sites. More at bit.ly/spliceAIWt
October 17, 2025 at 6:14 PM
We are pleased to announce the hg38 SpliceAI Wildtype tracks. These tracks show the scores for the genome sequence itself, without variants, from predicted splice donor and splice acceptor sites. More at bit.ly/spliceAIWt
We are happy to announce the hg38 Panmask Easy 151b Regions track. It contains a set of sample-agnostic easy regions where short-read variant calling reaches high accuracy and can be used to filter variant calls for clinical or research samples. More at bit.ly/Panmask
September 25, 2025 at 6:55 PM
We are happy to announce the hg38 Panmask Easy 151b Regions track. It contains a set of sample-agnostic easy regions where short-read variant calling reaches high accuracy and can be used to filter variant calls for clinical or research samples. More at bit.ly/Panmask
We are excited to announce the release of the CoLoRSdb small and structural variant tracks for the human assemblies GRCh38/hg38 and CHM13/hs1.
Learn more about this release at:
genome.ucsc.edu/gold...
Learn more about this release at:
genome.ucsc.edu/gold...
September 25, 2025 at 1:08 AM
We are excited to announce the release of the CoLoRSdb small and structural variant tracks for the human assemblies GRCh38/hg38 and CHM13/hs1.
Learn more about this release at:
genome.ucsc.edu/gold...
Learn more about this release at:
genome.ucsc.edu/gold...
We are pleased to announce the release of the Developmental Disorders Genotype-to-Phenotype (DDG2P) track for hg19 and hg38. The DDG2P track displays genes associated with severe developmental disorders.
Learn more at:
genome.ucsc.edu/gold...
Learn more at:
genome.ucsc.edu/gold...
September 19, 2025 at 8:08 PM
We are pleased to announce the release of the Developmental Disorders Genotype-to-Phenotype (DDG2P) track for hg19 and hg38. The DDG2P track displays genes associated with severe developmental disorders.
Learn more at:
genome.ucsc.edu/gold...
Learn more at:
genome.ucsc.edu/gold...
We are excited to announce the release of the MaveDB Experiment Heatmaps and Alignment track for hg38. Each heatmap shows the results of many small substitutions that were tested within a gene to examine their functional consequences.
Learn more at:
http://bit.ly/4lCIlLq
Learn more at:
http://bit.ly/4lCIlLq
August 21, 2025 at 10:11 PM
We are excited to announce the release of the MaveDB Experiment Heatmaps and Alignment track for hg38. Each heatmap shows the results of many small substitutions that were tested within a gene to examine their functional consequences.
Learn more at:
http://bit.ly/4lCIlLq
Learn more at:
http://bit.ly/4lCIlLq
New Capture long-seq (CLS) long-read lncRNAs tracks are available for hg38 and mm10. These tracks represent the results of targeted long-read RNA sequencing aimed at identifying lowly expressed lncRNAs.
See our news for more: bit.ly/CLSlongRead
See our news for more: bit.ly/CLSlongRead
August 13, 2025 at 4:43 PM
New Capture long-seq (CLS) long-read lncRNAs tracks are available for hg38 and mm10. These tracks represent the results of targeted long-read RNA sequencing aimed at identifying lowly expressed lncRNAs.
See our news for more: bit.ly/CLSlongRead
See our news for more: bit.ly/CLSlongRead
We are pleased to announce new PanelApp Australia tracks for hg38/hg19 in the PanelApp composite track. These display expert, crowdsourced diagnostic disease panels for genes, CNVs, and STRs, with data distinct from the Genomics England PanelApp. More at bit.ly/PanelAppAustr...
August 8, 2025 at 11:50 PM
We are pleased to announce new PanelApp Australia tracks for hg38/hg19 in the PanelApp composite track. These display expert, crowdsourced diagnostic disease panels for genes, CNVs, and STRs, with data distinct from the Genomics England PanelApp. More at bit.ly/PanelAppAustr...
We’re excited to announce support for bedMethyl and bigMethyl, new track formats for visualizing base-resolution DNA methylation from bisulfite sequencing or similar methods at single-base resolution across the genome in the UCSC Genome Browser. More info: genome.ucsc.edu/gold...
July 31, 2025 at 10:21 PM
We’re excited to announce support for bedMethyl and bigMethyl, new track formats for visualizing base-resolution DNA methylation from bisulfite sequencing or similar methods at single-base resolution across the genome in the UCSC Genome Browser. More info: genome.ucsc.edu/gold...
We’re adding two new UI features to the Genome Browser: a gear icon in the grey bar and an "X" to quickly remove tracks. We’d love your feedback—thanks for helping us improve!
🔗 forms.gle/s2QnMrbEYu...
🔗 forms.gle/s2QnMrbEYu...
July 29, 2025 at 7:18 PM
We’re adding two new UI features to the Genome Browser: a gear icon in the grey bar and an "X" to quickly remove tracks. We’d love your feedback—thanks for helping us improve!
🔗 forms.gle/s2QnMrbEYu...
🔗 forms.gle/s2QnMrbEYu...
New ENCODE4 long-read RNA-seq transcripts track for hg38 and mm10. Triplets (e.g. [1,1,3]) indicate start site, exon combination, and stop site for each transcript. Enrichment scores show how these change across tissue and cell line samples.
Read more: genome.ucsc.edu/gold...
Read more: genome.ucsc.edu/gold...
July 16, 2025 at 6:27 PM
New ENCODE4 long-read RNA-seq transcripts track for hg38 and mm10. Triplets (e.g. [1,1,3]) indicate start site, exon combination, and stop site for each transcript. Enrichment scores show how these change across tissue and cell line samples.
Read more: genome.ucsc.edu/gold...
Read more: genome.ucsc.edu/gold...
We have two new pathogenicity prediction score tracks available in our Deleteriousness Predictions super track: MCAP and MutScore!
Both are aimed at interpreting the pathogenicity of variants in a clinical setting.
See our news for more: bit.ly/UCSCmutScoreMCAP
Both are aimed at interpreting the pathogenicity of variants in a clinical setting.
See our news for more: bit.ly/UCSCmutScoreMCAP
July 15, 2025 at 10:01 PM
We have two new pathogenicity prediction score tracks available in our Deleteriousness Predictions super track: MCAP and MutScore!
Both are aimed at interpreting the pathogenicity of variants in a clinical setting.
See our news for more: bit.ly/UCSCmutScoreMCAP
Both are aimed at interpreting the pathogenicity of variants in a clinical setting.
See our news for more: bit.ly/UCSCmutScoreMCAP
We turn 25 today!
July 7th marks the 25th anniversary of the human genome going online and the start of the UCSC Genome Browser.
Then vs. now, we have 165k monthly visitors, and our codebase is over three million lines of code.
See our news for more: bit.ly/genomeBrowser...
July 7th marks the 25th anniversary of the human genome going online and the start of the UCSC Genome Browser.
Then vs. now, we have 165k monthly visitors, and our codebase is over three million lines of code.
See our news for more: bit.ly/genomeBrowser...
July 7, 2025 at 9:45 PM
We turn 25 today!
July 7th marks the 25th anniversary of the human genome going online and the start of the UCSC Genome Browser.
Then vs. now, we have 165k monthly visitors, and our codebase is over three million lines of code.
See our news for more: bit.ly/genomeBrowser...
July 7th marks the 25th anniversary of the human genome going online and the start of the UCSC Genome Browser.
Then vs. now, we have 165k monthly visitors, and our codebase is over three million lines of code.
See our news for more: bit.ly/genomeBrowser...
We have a new training page with updated tutorials covering our most popular tools. Each includes an annotated screenshot, guided walkthroughs, and an interactive click-through tutorial.
See our news for more: bit.ly/genomeBrowser...
See our news for more: bit.ly/genomeBrowser...
June 26, 2025 at 10:51 PM
We have a new training page with updated tutorials covering our most popular tools. Each includes an annotated screenshot, guided walkthroughs, and an interactive click-through tutorial.
See our news for more: bit.ly/genomeBrowser...
See our news for more: bit.ly/genomeBrowser...
We are happy to announce the release of the EVA SNP Release 7 tracks, now available for 40 assemblies and covering nearly 910 million variants.
Learn more at http://genome.ucsc.e....
Learn more at http://genome.ucsc.e....
June 12, 2025 at 7:44 PM
We are happy to announce the release of the EVA SNP Release 7 tracks, now available for 40 assemblies and covering nearly 910 million variants.
Learn more at http://genome.ucsc.e....
Learn more at http://genome.ucsc.e....
We are excited to announce the release of the Varaico tracks for human assemblies hg38 and hg19. Varaico stands for "Variation Research Advancing Insight in Complex Organisms". Varaico was created using literature mining, similar to AVADA.
Learn more at:
genome.ucsc.edu/gold...
Learn more at:
genome.ucsc.edu/gold...
May 21, 2025 at 11:57 PM
We are excited to announce the release of the Varaico tracks for human assemblies hg38 and hg19. Varaico stands for "Variation Research Advancing Insight in Complex Organisms". Varaico was created using literature mining, similar to AVADA.
Learn more at:
genome.ucsc.edu/gold...
Learn more at:
genome.ucsc.edu/gold...
The pext track is also present in our new Exon Relevance RTS, which can assist in variant interpretation by evaluating if the variant is present in an exon required for the gene product's function.
See our news for more: bit.ly/ExonRelevance...
See our news for more: bit.ly/ExonRelevance...
May 16, 2025 at 6:35 PM
The pext track is also present in our new Exon Relevance RTS, which can assist in variant interpretation by evaluating if the variant is present in an exon required for the gene product's function.
See our news for more: bit.ly/ExonRelevance...
See our news for more: bit.ly/ExonRelevance...
We have a new Recommended Track Set (RTS), Exon Relevance, and a new track, gnomAD Proportion Expression Across Transcript Scores (pext) for hg38.
The pext track shows @gnomad-project.bsky.social data in combination with GTExV10 to compute a metric quantifying isoform expression for variants.
The pext track shows @gnomad-project.bsky.social data in combination with GTExV10 to compute a metric quantifying isoform expression for variants.
May 16, 2025 at 6:35 PM
We have a new Recommended Track Set (RTS), Exon Relevance, and a new track, gnomAD Proportion Expression Across Transcript Scores (pext) for hg38.
The pext track shows @gnomad-project.bsky.social data in combination with GTExV10 to compute a metric quantifying isoform expression for variants.
The pext track shows @gnomad-project.bsky.social data in combination with GTExV10 to compute a metric quantifying isoform expression for variants.
Announcing the new Pseudogenes track for hg38! The composite track contains pseudogene predictions and their corresponding parent genes, as identified by PseudoPipe. This release includes the Pseudogene Parents and Pseudogenes tracks.
Learn more at genome.ucsc.edu/gold....
Learn more at genome.ucsc.edu/gold....
March 31, 2025 at 11:40 PM
Announcing the new Pseudogenes track for hg38! The composite track contains pseudogene predictions and their corresponding parent genes, as identified by PseudoPipe. This release includes the Pseudogene Parents and Pseudogenes tracks.
Learn more at genome.ucsc.edu/gold....
Learn more at genome.ucsc.edu/gold....
We are excited to share new AlphaMissense tracks for the hg38/hg19 human assemblies. AlphaMissense scores predict the pathogenicity of missense variants for all possible single amino acid substitutions in the human proteome.
See our news for more: genome.ucsc.edu/gold...
See our news for more: genome.ucsc.edu/gold...
March 12, 2025 at 2:30 AM
We are excited to share new AlphaMissense tracks for the hg38/hg19 human assemblies. AlphaMissense scores predict the pathogenicity of missense variants for all possible single amino acid substitutions in the human proteome.
See our news for more: genome.ucsc.edu/gold...
See our news for more: genome.ucsc.edu/gold...
We are pleased to announce the release of the MITOMAP track for hg38/hg19. MITOMAP is a human mitochondrial genome database. This release includes the MITOMAP Control and Coding Variants track & the MITOMAP Disease Mutations track.
Learn more at genome.ucsc.edu/gold....
Learn more at genome.ucsc.edu/gold....
March 6, 2025 at 11:45 PM
We are pleased to announce the release of the MITOMAP track for hg38/hg19. MITOMAP is a human mitochondrial genome database. This release includes the MITOMAP Control and Coding Variants track & the MITOMAP Disease Mutations track.
Learn more at genome.ucsc.edu/gold....
Learn more at genome.ucsc.edu/gold....
We are excited to announce the new Splicing Impact super track for hg38 and hg19. This super track includes AbSplice Scores, SpliceAI, and, for hg38, the new SpliceVarDB track. Learn more at http://genome.ucsc.e....
March 5, 2025 at 8:17 PM
We are excited to announce the new Splicing Impact super track for hg38 and hg19. This super track includes AbSplice Scores, SpliceAI, and, for hg38, the new SpliceVarDB track. Learn more at http://genome.ucsc.e....
We are happy to announce the release of new highlight features for track hubs. Items can now be striped with a colored background to appear "highlighted" compared to the other items in the display.
Learn more about this release at:
genome.ucsc.edu/gold...
Learn more about this release at:
genome.ucsc.edu/gold...
March 3, 2025 at 11:24 PM
We are happy to announce the release of new highlight features for track hubs. Items can now be striped with a colored background to appear "highlighted" compared to the other items in the display.
Learn more about this release at:
genome.ucsc.edu/gold...
Learn more about this release at:
genome.ucsc.edu/gold...
We are excited to announce the release of the enGenome VarChat track for hg38 and hg19. This track uses AI to search papers for variants, providing information such as its gene, HGVS nomenclature, and dbSNP rsID. Learn more at genome.ucsc.edu/gold....
February 24, 2025 at 10:29 PM
We are excited to announce the release of the enGenome VarChat track for hg38 and hg19. This track uses AI to search papers for variants, providing information such as its gene, HGVS nomenclature, and dbSNP rsID. Learn more at genome.ucsc.edu/gold....
The Clinical Interpretation of Variants in Cancer (CIViC) track for hg19/GRCh37 and hg38/GRCh38 is now available. The details page for a feature will list diseases and therapies that have been associated with a genomic variant.
Learn more at:
genome.ucsc.edu/gold...
Learn more at:
genome.ucsc.edu/gold...
February 20, 2025 at 10:48 PM
The Clinical Interpretation of Variants in Cancer (CIViC) track for hg19/GRCh37 and hg38/GRCh38 is now available. The details page for a feature will list diseases and therapies that have been associated with a genomic variant.
Learn more at:
genome.ucsc.edu/gold...
Learn more at:
genome.ucsc.edu/gold...