Gene Ontology
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geneontology.bsky.social
Gene Ontology
@geneontology.bsky.social
950 followers 16 following 110 posts
The Gene Ontology (GO, geneontology.org) knowledgebase is the world’s largest source of information on gene function. Our mission is to develop a comprehensive, computational model of biological systems, ranging from the molecular to organism level.
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geneontology.bsky.social
It's started!

If you're not in Geneva right now you're missing out on the 2025 Spring GOC Meeting! If you've registered to attend remotely, please check your emails for links. Recordings will be available to GOC members and registered guests shortly after the meeting.
Photo of the fountain on Lake Geneva, taken by Tuyet Nguyen
May 6, 2025 at 8:19 AM
geneontology.bsky.social
Last chance to register for the upcoming Spring GOC Meeting!

To all Consortium members, if you're planning on coming in-person to the meeting next month in Geneva, remember to register today! Check your email for the registration link, agenda, and hotel info.
April 8, 2025 at 8:09 PM
geneontology.bsky.social
You know about the PAN-GO #Functionome, but have you explored the power of the Functional Category search? Learn how to find #humangenes of interest in just a few clicks, using the Functional Categories

community.alliancegenome.org/t/8362

🧬🧪 #GOSlims

ICYMI: community.alliancegenome.org/t/8343
March 12, 2025 at 11:17 PM
geneontology.bsky.social
The PAN-GO #Functionome was announced last week in @nature.com-but do you know how to use it?

Here's how to find functions for a selected human #gene:
➡️ community.alliancegenome.org/t/8353

ICYMI, more on the PAN-GO Functionome:
💡 community.alliancegenome.org/t/8343

🧪🧬 #science #research #human
GIF of how to use the PAN-GO Functionome website to find functions for a specific human gene; stationary slides are available in the Alliance Forums linked in post
March 3, 2025 at 11:47 PM
geneontology.bsky.social
Immediately address any missing or incorrect functions!
Contact us to have information added, altered, or removed
February 26, 2025 at 9:59 PM
geneontology.bsky.social
To perform a GO enrichment, paste a list of genes here. You can even load our sample list to try it out immediately!
February 26, 2025 at 9:59 PM
geneontology.bsky.social
The functional categories displayed in the graph can be filtered by selecting one, two, or all (default) categories here
February 26, 2025 at 9:59 PM
geneontology.bsky.social
The number of genes in each high-level functional category is shown in this graph, which is hidden by default on some mobile devices
February 26, 2025 at 9:59 PM
geneontology.bsky.social
The functional characteristics
(GO annotations) of each gene are here, divided by functional category (GO subset):
* Molecular Function
* Biological Process
* Cellular Component
February 26, 2025 at 9:59 PM
geneontology.bsky.social
When you start, you’re looking at the list of all protein coding genes
February 26, 2025 at 9:59 PM
geneontology.bsky.social
THE PAN-GO #FUNCTIONOME IS LIVE! Read our brand new #openaccess @nature.com paper and explore the PAN-GO Functionome, our most accurate and complete resource ever!

Paper links, press release, how to contribute and more on the @alliancegenome.bsky.social Forums: community.alliancegenome.org/t/8343
short animation of the various features of the functionome.geneontology.org website
February 26, 2025 at 9:50 PM
geneontology.bsky.social
Forgot to register for Quest for Orthologs 2024? Registration AND abstract submission dates have been extended to May 14!! Act now and join QFO8 in Montreal this July 17-18, right after ISCB's ISMB:
event.fourwaves.com/qfo8/pages
May 8, 2024 at 11:47 PM
geneontology.bsky.social
Don't be the weak link! If you link to GO terms, GO_REFs, GO-CAMs, or the ontology, make sure you're using PURLs. Read more: community.alliancegenome.org/t/best-pract...

🧪
May 7, 2024 at 12:02 AM
geneontology.bsky.social
Best way to celebrate #itsgonnabemay? A bonus GO release to wrap up April! Details for the new, second April release (2024-04-24):
🧪

community.alliancegenome.org/t/second-apr...
April 30, 2024 at 10:49 PM
geneontology.bsky.social
Holy Pathways, Batman! Did you know you can find GO-powered Pathways on @alliancegenome.bsky.social pages? community.alliancegenome.org/t/go-cams-on...
April 29, 2024 at 11:58 PM
geneontology.bsky.social
Happy #DNADay2024! 🧬

Today's @alliancegenome.bsky.social forum post highlights some of the close ties between the Human Genome Project and the #GeneOntology: both Dr. David Botstein and Dr. Paul Thomas.
community.alliancegenome.org/t/happy-dna-...
🧪
April 25, 2024 at 10:39 PM
geneontology.bsky.social
Rice, wheat, bamboo, maize... the Poaceae family is immense. Read the new Nature Communications publication that looks at WGD in the massive grass family:
#wholegenomeduplication 🧪

community.alliancegenome.org/t/go-and-who...
April 24, 2024 at 11:36 PM
geneontology.bsky.social
Ever try to look up a term in AmiGO, but the results included extra terms? That's a feature not a 🐞! Read about how we use closures to show you ontology search results- and how you can restrict this if needed
🧪
community.alliancegenome.org/t/tuesdaytip...
April 23, 2024 at 11:49 PM
geneontology.bsky.social
New GO release! 2024-04-18 is available now!
current.geneontology.org
release.geneontology.org/2024-04-18 10.5281/zenodo.10999780
🧪

42,271 GO terms
7,668,043 annotations
1,536,109 gene products
5,404 species
More info & release notes:
community.alliancegenome.org/t/april-2024...
April 22, 2024 at 11:46 PM
geneontology.bsky.social
It's now more crucial than ever to cite resources you wish to keep using- GO, @alliancegenome.bsky.social, etc. In addition to citing these references, GO asks users/tool devs/etc. to include the GO Release. Does GO really change that much?... Yes! 🧪
community.alliancegenome.org/t/archive-of...
April 18, 2024 at 10:42 PM
geneontology.bsky.social
Today's paper highlight: new Scientific Reports publication that uses #GeneOntology and could help advance research on liver cancer #CancerResearch
🧪

community.alliancegenome.org/t/go-and-hep...
April 17, 2024 at 11:39 PM
geneontology.bsky.social
#TuesdayTips: Did you know there's a free #OpenAccess GO Handbook? We're highlighting the first chapter, which is an overview of #ontologies in general:
🧪

community.alliancegenome.org/t/go-handboo...
April 16, 2024 at 9:45 PM
geneontology.bsky.social
Sugar: eating it is easy... studying the ~9Gb sugarcane genome, not so easy. Read how Bao et al. assembled the ultra-complex modern hybrid sugarcane genome, and how GO helped identify important genes
community.alliancegenome.org/t/go-and-hyb...
🧪🌾
April 13, 2024 at 1:17 AM
geneontology.bsky.social
Quest for Orthologs 2024: if orthology predictions are your thing, you need to be in Montreal this summer!
🧪
Meeting info:
➡️ QfO-8 website: event.fourwaves.com/qfo8/pages
📣 Sharable meeting announcement:
community.alliancegenome.org/t/quest-for-...
April 11, 2024 at 10:44 PM
geneontology.bsky.social
GO is meant to be computer readable- but do you know anything about the group of people that maintain the GO knowledgebase?
community.alliancegenome.org/t/the-people...
🧪
April 9, 2024 at 11:25 PM