Climate Change and Maternal Child Health Lab
@gayenlab-iisc.bsky.social
Lab handle of Srimonta Gayen, Associate Professor, DBG, IISc Bangalore.
Interested in DevBio, epigenetics, XCI-XCU, environment-epigenome crosstalk during development.
Interested in DevBio, epigenetics, XCI-XCU, environment-epigenome crosstalk during development.
Reposted by Climate Change and Maternal Child Health Lab
We are excited to share our new preprint:
SMARCA2/4-Dependent Chromatin Remodelling Establishes Gene Regulatory Programs in Early Human Embryos and Blastoids.
www.biorxiv.org/content/10.64898/2025.12.01.691499v1
SMARCA2/4-Dependent Chromatin Remodelling Establishes Gene Regulatory Programs in Early Human Embryos and Blastoids.
www.biorxiv.org/content/10.64898/2025.12.01.691499v1
December 3, 2025 at 6:53 PM
We are excited to share our new preprint:
SMARCA2/4-Dependent Chromatin Remodelling Establishes Gene Regulatory Programs in Early Human Embryos and Blastoids.
www.biorxiv.org/content/10.64898/2025.12.01.691499v1
SMARCA2/4-Dependent Chromatin Remodelling Establishes Gene Regulatory Programs in Early Human Embryos and Blastoids.
www.biorxiv.org/content/10.64898/2025.12.01.691499v1
Reposted by Climate Change and Maternal Child Health Lab
So exciting to see this in print! Ever wondered how embryonic cells know what (fate) to become during early development? In particular when they might see different signaling cues? We investigated this!
And a lovely cover from Zoe Ruiz and @oliveringe.bsky.social!
www.cell.com/developmenta...
And a lovely cover from Zoe Ruiz and @oliveringe.bsky.social!
www.cell.com/developmenta...
Combinatorial BMP4 and activin direct the choice between alternate routes to endoderm in a stem cell model of human gastrulation
Inge et al. show that human endoderm originates from two converging developmental
routes with distinct dynamics and efficiencies yet similar developmental potential.
Combinatorial activin and BMP4 sig...
www.cell.com
December 2, 2025 at 1:47 PM
So exciting to see this in print! Ever wondered how embryonic cells know what (fate) to become during early development? In particular when they might see different signaling cues? We investigated this!
And a lovely cover from Zoe Ruiz and @oliveringe.bsky.social!
www.cell.com/developmenta...
And a lovely cover from Zoe Ruiz and @oliveringe.bsky.social!
www.cell.com/developmenta...
XCI-ited to share that @Runumi from our lab recently attended the Gordon Research Conference on "Epigenetic Variation: Mechanisms and Impact across Systems" held in Barcelona, Spain. She presented her work on role of #m6A-RNA in #embryogenesis and dosage compensation #X-inactivation.
November 24, 2025 at 5:54 AM
XCI-ited to share that @Runumi from our lab recently attended the Gordon Research Conference on "Epigenetic Variation: Mechanisms and Impact across Systems" held in Barcelona, Spain. She presented her work on role of #m6A-RNA in #embryogenesis and dosage compensation #X-inactivation.
Thrilled to share that @Avinchal from our lab presented her work on effect of heat-humidity stress on fetal development and #epigenetic regulation in the recent #GordonConference on "Epigenetic Variation: Mechanisms and Impact across Systems" #ClimateChange #GlobalWarming #MaternalChildHealth
November 21, 2025 at 12:59 PM
Thrilled to share that @Avinchal from our lab presented her work on effect of heat-humidity stress on fetal development and #epigenetic regulation in the recent #GordonConference on "Epigenetic Variation: Mechanisms and Impact across Systems" #ClimateChange #GlobalWarming #MaternalChildHealth
Interesting study showing how H3K36me2 modulation is critical for post-implantation DNAme re-establishment. #epigenetics #histone #EarlyDevelopment
Epigenetics Update – Reprogramming of H3K36me2 guides lineage-specific post-implantation de novo DNA methylation go.nature.com/43jkfzm
#Epigenetics #DNAm #H3K36me2 #Development
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High-resolution insights without cell sorting; epigenometech.com
#Epigenetics #DNAm #H3K36me2 #Development
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High-resolution insights without cell sorting; epigenometech.com
November 13, 2025 at 5:11 AM
Interesting study showing how H3K36me2 modulation is critical for post-implantation DNAme re-establishment. #epigenetics #histone #EarlyDevelopment
Reposted by Climate Change and Maternal Child Health Lab
Excited to receive the Best Poster Award at the 9th Asian chromatin meeting 2025 in IISER Pune! Huge thanks to my mentor Srimonta for his guidance. Thanks to organizers of #ACM2025 for this wonderful opportunity!
#iiscbangalore #EMBO
#iiscbangalore #EMBO
November 7, 2025 at 5:44 AM
Excited to receive the Best Poster Award at the 9th Asian chromatin meeting 2025 in IISER Pune! Huge thanks to my mentor Srimonta for his guidance. Thanks to organizers of #ACM2025 for this wonderful opportunity!
#iiscbangalore #EMBO
#iiscbangalore #EMBO
Runumi, from our lab, had a fantastic week at the @embo.org Epitranscriptome workshop at EMBL Heidelberg! She presented her work on the role of m6A RNA modification in #embryogenesis #stemcell specification and #Xinactivation. #EMBOEpitrans
Thanks to IISc, ANRF-India, DBT-India, @insdb.bsky.social
Thanks to IISc, ANRF-India, DBT-India, @insdb.bsky.social
November 7, 2025 at 5:37 AM
Runumi, from our lab, had a fantastic week at the @embo.org Epitranscriptome workshop at EMBL Heidelberg! She presented her work on the role of m6A RNA modification in #embryogenesis #stemcell specification and #Xinactivation. #EMBOEpitrans
Thanks to IISc, ANRF-India, DBT-India, @insdb.bsky.social
Thanks to IISc, ANRF-India, DBT-India, @insdb.bsky.social