David Turner
@gastruloids.bsky.social
Stem cell and developmental biologist at the University of Liverpool
Huge thanks to @cci-liv.bsky.social for the amazing microscopes and technical support throughout this work!
June 30, 2025 at 7:50 AM
Huge thanks to @cci-liv.bsky.social for the amazing microscopes and technical support throughout this work!
Reposted by David Turner
We previously showed that DNA Typewriter can record high-resolution lineage trees in cultured cells (HEK293T). www.nature.com/articles/s41... But could we use it to study how clonal memory shapes cell fate decisions during development? (2/13)
A time-resolved, multi-symbol molecular recorder via sequential genome editing - Nature
A DNA memory device, DNA Typewriter, uses sequential prime editing to record the order of multiple cellular events.
www.nature.com
May 27, 2025 at 2:57 PM
We previously showed that DNA Typewriter can record high-resolution lineage trees in cultured cells (HEK293T). www.nature.com/articles/s41... But could we use it to study how clonal memory shapes cell fate decisions during development? (2/13)