I unfortunately have to conclude that my testing setup likely is flawed, and that in these circumstances (single person in a world, running on desktop) the differences are more likely explained by measuring error and me as a player not being able to replicate movements 100% exactly in both runs

With the settings recommended by you for the profile inspector, it causes a observable visual difference in VRchat: The VRchat menu should be transparent, it is now opaque.
Looking back through the list of changes, the change to texture filtering seems like the most likely culprit.

As you can see, frame time data and fps data for some reason don't seem to line up. I'm not entirely sure what could be causing this issue. That's however not the biggest problem.

My fourth artfight attack this season, attacking Cowboyhell artfight.net/attack/12219...

Third artfight attack this season: Attacking @f4celess.bsky.social artfight.net/attack/11087...
(This one is a 3d model, as opposed to my other attacks, which are just drawings)

My second artfight attack this season: attacking @byinky.bsky.social artfight.net/attack/10221...

My first artfight attack this season, attacking @Elitelexx.bsky.social artfight.net/attack/90755...