Gabriel Esteban Valdebenito
gabbov.bsky.social
Gabriel Esteban Valdebenito
@gabbov.bsky.social
Postdoctoral Fellow at MGH and Harvard Medical School 🇺🇸 Previously at University College London 🇬🇧
Very cool to see more work exploring how NAD availability and redox state shape developmental tempo. Congrats to Nisha and Francois on this preprint!
How is developmental speed regulated ? 🪰

Happy to share my PhD story from Schweisguth Lab @devstempasteur.bsky.social. Here we show that cellular NAD+ availability and redox constrain developmental speed in the fly eye.

www.biorxiv.org/content/10.1...

A big thanks to everyone involved!
November 14, 2025 at 12:40 AM
its lasers?
A peacock showing off its art.
August 6, 2025 at 2:50 AM
Reposted by Gabriel Esteban Valdebenito
In preprints: setting the tempo of development

@gabbov.bsky.social and @mdiazcuadros.bsky.social highlight two preprints that describe how developmental timing is set by cell-intrinsic mechanisms.

journals.biologists.com/dev/article/...
July 25, 2025 at 2:11 PM
Reposted by Gabriel Esteban Valdebenito
New In Preprints from @dev-journal.bsky.social by Valdebenito & Diaz-Cuadros

Highlights recent work investigating how the rate of development is controlled from @trayon.bsky.social & Coussement et al

In preprints: setting the tempo of development url: journals.biologists.com/dev/article/...
In preprints: setting the tempo of development | Development | The Company of Biologists
journals.biologists.com
July 25, 2025 at 8:09 AM
Thrilled to have written this piece for Development’s “In Preprints” series!

I got to comment on two amazing preprints that explore how embryos set their pace of development.

Check it out here 👇
👉
journals.biologists.com/dev/article/...
In preprints: setting the tempo of development | Development | The Company of Biologists
journals.biologists.com
July 21, 2025 at 4:58 PM
Inhibition of the PI3K-AKT-MTORC1 axis reduces the burden of the m.3243A>G mtDNA mutation by promoting mitophagy and improving mitochondrial function

www.tandfonline.com/doi/full/10....
Inhibition of the PI3K-AKT-MTORC1 axis reduces the burden of the m.3243A>G mtDNA mutation by promoting mitophagy and improving mitochondrial function
Mitochondrial DNA (mtDNA) encodes genes essential for oxidative phosphorylation. The m.3243A>G mutation causes severe disease, including myopathy, lactic acidosis and stroke-like episodes (MELAS) a...
www.tandfonline.com
December 13, 2024 at 8:09 PM
Hi academic Twitter, I mean, bluesky people!
December 4, 2024 at 1:03 AM
Reposted by Gabriel Esteban Valdebenito
📢New preprint alert 📢
Somite-independent regeneration of the axolotl primary body axis. biorxiv.org/content/10.110…
This is the combined effort of a fantastic group of people over many years. Read below to see why you should care⬇️ 1/8
February 3, 2024 at 5:18 PM