A reduction in apical/basal tension, on the other hand, would produce extensive cell extrusion after a period of relative stability. When extrapolated to a living tissue, these observations could be explained by cell-cell and cell-matrix adhesion, relying on F-actin-generated tension across cells.

Making a long story short, and skipping the quantitative part (if interested, ask Santi), what we found is that the relatively crowded simulated pseudostratified epithelium was stable as long as apical/basal tension was kept high relative to lateral tension. An example is reproduced in the video.

So, what do we do at the CBND? This 20-yo video summarizes a lot of it, all around neuroepithelial cell polarity and its transition to neuronal polarity, largely on the retina, but also looking at morphogenetic processes like neurulation. Mostly on zebrafish, a bit on chick. Look at the ALT text!