Benjamin Friedrich
@friedrich-group.bsky.social
Biological algorithms of cell motility and pattern formation in active living matter, using theoretical physics https://physics-of-life.tu-dresden.de/friedrich
Pinned
Fully-funded PhD position at @poldresden.bsky.social in Dresden, Germany, to theoretically study sarcomere self-assembly in muscle cells, in collaboration with the experimental group of Frank Schnorrer @frankschnorrer.bsky.social
More information here:
physics-of-life.tu-dresden.de/friedrich
More information here:
physics-of-life.tu-dresden.de/friedrich
Reposted by Benjamin Friedrich
Why do secondary #tumors go for #MET during the metastatic cascade? Our new study suggests that immune evasion—rather than faster proliferation—might give them the edge.
👉 cell.com/iscience/ful...
#CancerResearch #TumorBiology #Immunology #Metastasis
👉 cell.com/iscience/ful...
#CancerResearch #TumorBiology #Immunology #Metastasis
Mesenchymal-epithelial transition reduces proliferation but increases immune evasion in tumor spheroids
Microenvironment; Biological process; Cancer
cell.com
August 3, 2025 at 6:59 PM
Why do secondary #tumors go for #MET during the metastatic cascade? Our new study suggests that immune evasion—rather than faster proliferation—might give them the edge.
👉 cell.com/iscience/ful...
#CancerResearch #TumorBiology #Immunology #Metastasis
👉 cell.com/iscience/ful...
#CancerResearch #TumorBiology #Immunology #Metastasis
Reposted by Benjamin Friedrich
How do individual proteins sculpt the epithelial basement membrane?
Our new study uncovers their role in network structure, nematic alignment & fractal patterns.
🔗 www.sciencedirect.com/science/arti...
#CellBiology #ECM #BasementMembrane
Our new study uncovers their role in network structure, nematic alignment & fractal patterns.
🔗 www.sciencedirect.com/science/arti...
#CellBiology #ECM #BasementMembrane
August 3, 2025 at 7:19 PM
How do individual proteins sculpt the epithelial basement membrane?
Our new study uncovers their role in network structure, nematic alignment & fractal patterns.
🔗 www.sciencedirect.com/science/arti...
#CellBiology #ECM #BasementMembrane
Our new study uncovers their role in network structure, nematic alignment & fractal patterns.
🔗 www.sciencedirect.com/science/arti...
#CellBiology #ECM #BasementMembrane
Reposted by Benjamin Friedrich
Fabulous job call @tudresden.bsky.social @cmcb-tud.bsky.social @dcgenomecenter.bsky.social is looking for a new head. Post is for two years in the first instance, remunerated at group leader level with lots of opportunity to drive development and science
www.verw.tu-dresden.de/StellAus/ste...
www.verw.tu-dresden.de/StellAus/ste...
Vacancy ID 12257
www.verw.tu-dresden.de
July 9, 2025 at 1:17 PM
Fabulous job call @tudresden.bsky.social @cmcb-tud.bsky.social @dcgenomecenter.bsky.social is looking for a new head. Post is for two years in the first instance, remunerated at group leader level with lots of opportunity to drive development and science
www.verw.tu-dresden.de/StellAus/ste...
www.verw.tu-dresden.de/StellAus/ste...
Sarcomeres are the contractile units of muscle 💪. During development, sarcomeres divide to add new sarcomeres - out now and on the cover. Great work by @clementrodier.bsky.social Ian Estabrook @frankschnorrer.bsky.social at @ibdm.bsky.social & @poldresden.bsky.social: doi.org/10.1126/scia...
July 10, 2025 at 11:12 AM
Sarcomeres are the contractile units of muscle 💪. During development, sarcomeres divide to add new sarcomeres - out now and on the cover. Great work by @clementrodier.bsky.social Ian Estabrook @frankschnorrer.bsky.social at @ibdm.bsky.social & @poldresden.bsky.social: doi.org/10.1126/scia...
Reposted by Benjamin Friedrich
🎉Paper alert!
Congratulations to the Friedrich group at PoL @friedrich-group.bsky.social and collaborators for their new findings (+cover!) published in Science Advances. They reveal a novel mechanism for muscle growth via division of sarcomeres, throughout myofibrils
Learn more: tud.link/35mkgk
Congratulations to the Friedrich group at PoL @friedrich-group.bsky.social and collaborators for their new findings (+cover!) published in Science Advances. They reveal a novel mechanism for muscle growth via division of sarcomeres, throughout myofibrils
Learn more: tud.link/35mkgk
Sarcomere Division: A New Mechanism of Muscle Growth Under Tension
Researchers from the Friedrich group at PoL have identified a novel sarcomere division mechanism, explaining how muscles add new contractile units under high mechanical stress.
tud.link
July 10, 2025 at 8:31 AM
🎉Paper alert!
Congratulations to the Friedrich group at PoL @friedrich-group.bsky.social and collaborators for their new findings (+cover!) published in Science Advances. They reveal a novel mechanism for muscle growth via division of sarcomeres, throughout myofibrils
Learn more: tud.link/35mkgk
Congratulations to the Friedrich group at PoL @friedrich-group.bsky.social and collaborators for their new findings (+cover!) published in Science Advances. They reveal a novel mechanism for muscle growth via division of sarcomeres, throughout myofibrils
Learn more: tud.link/35mkgk
Wonderful theory-experiment collaboration with @frankschnorrer.bsky.social on muscle growth: by detecting and analyzing thousands of sarcomeres, we discovered a mechanism of tension-driven sarcomere addition: a mother sarcomeres divide daughter sarcomeres - now out: www.science.org/doi/10.1126/...
July 10, 2025 at 10:31 AM
Wonderful theory-experiment collaboration with @frankschnorrer.bsky.social on muscle growth: by detecting and analyzing thousands of sarcomeres, we discovered a mechanism of tension-driven sarcomere addition: a mother sarcomeres divide daughter sarcomeres - now out: www.science.org/doi/10.1126/...
Reposted by Benjamin Friedrich
Outstanding success: 🎉 #TUDresden shines with 5 Clusters of Excellence. @dfg.de & @wissenschaftsrat.de announced that decision today. TUD has impressively proven its claim to be a top university for the 21st century.
ℹ️ tu-dresden.de/tu-dresden/n...
ℹ️ tu-dresden.de/tu-dresden/n...
May 22, 2025 at 4:54 PM
Outstanding success: 🎉 #TUDresden shines with 5 Clusters of Excellence. @dfg.de & @wissenschaftsrat.de announced that decision today. TUD has impressively proven its claim to be a top university for the 21st century.
ℹ️ tu-dresden.de/tu-dresden/n...
ℹ️ tu-dresden.de/tu-dresden/n...
Reposted by Benjamin Friedrich
The #ClustersOfExcellence have been selected: today, the Excellence Commission approved 70 projects for funding. 45 clusters will continue and 25 will be newly established. Funding starts on 1 Jan 2026 for 7 years, with €539 million per year. The full list: www.dfg.de/resource/blo... 1/3
May 22, 2025 at 6:10 PM
The #ClustersOfExcellence have been selected: today, the Excellence Commission approved 70 projects for funding. 45 clusters will continue and 25 will be newly established. Funding starts on 1 Jan 2026 for 7 years, with €539 million per year. The full list: www.dfg.de/resource/blo... 1/3
Reposted by Benjamin Friedrich
Good news: there will be 3 scholarships available for Physics of Life MSc students starting in 2025!
✅ €300/month for 1 year
✅ No separate application—admitted students are automatically considered.
Apply now ➡️ tud.link/vejrmx
#Biophysics #PhysicsofLife #StudyinGermany #Masters #Biology
✅ €300/month for 1 year
✅ No separate application—admitted students are automatically considered.
Apply now ➡️ tud.link/vejrmx
#Biophysics #PhysicsofLife #StudyinGermany #Masters #Biology
April 22, 2025 at 8:45 AM
Good news: there will be 3 scholarships available for Physics of Life MSc students starting in 2025!
✅ €300/month for 1 year
✅ No separate application—admitted students are automatically considered.
Apply now ➡️ tud.link/vejrmx
#Biophysics #PhysicsofLife #StudyinGermany #Masters #Biology
✅ €300/month for 1 year
✅ No separate application—admitted students are automatically considered.
Apply now ➡️ tud.link/vejrmx
#Biophysics #PhysicsofLife #StudyinGermany #Masters #Biology
Reposted by Benjamin Friedrich
One week left to apply to the Physics of Life MSc this year! Students learn first-class research skills and can also avail of #scholarships to aid their studies.
Learn more and apply: physics-of-life.tu-dresden.de/career-educa...
#internationalstudents #MSc #EnglishMSc #Physics #studyabroad
Learn more and apply: physics-of-life.tu-dresden.de/career-educa...
#internationalstudents #MSc #EnglishMSc #Physics #studyabroad
Good news: there will be 3 scholarships available for Physics of Life MSc students starting in 2025!
✅ €300/month for 1 year
✅ No separate application—admitted students are automatically considered.
Apply now ➡️ tud.link/vejrmx
#Biophysics #PhysicsofLife #StudyinGermany #Masters #Biology
✅ €300/month for 1 year
✅ No separate application—admitted students are automatically considered.
Apply now ➡️ tud.link/vejrmx
#Biophysics #PhysicsofLife #StudyinGermany #Masters #Biology
May 21, 2025 at 9:39 AM
One week left to apply to the Physics of Life MSc this year! Students learn first-class research skills and can also avail of #scholarships to aid their studies.
Learn more and apply: physics-of-life.tu-dresden.de/career-educa...
#internationalstudents #MSc #EnglishMSc #Physics #studyabroad
Learn more and apply: physics-of-life.tu-dresden.de/career-educa...
#internationalstudents #MSc #EnglishMSc #Physics #studyabroad
Reposted by Benjamin Friedrich
Delighted that our work on positional memory is now published. We asked how axolotl cells 'know' which part of the limb to regenerate after injury.
www.nature.com/articles/s41...
A joy to work with super team Sarah Plattner, Yuka Sugiura, Francisco Falcon and Elly Tanaka.
🧵1/14
www.nature.com/articles/s41...
A joy to work with super team Sarah Plattner, Yuka Sugiura, Francisco Falcon and Elly Tanaka.
🧵1/14
May 21, 2025 at 3:05 PM
Delighted that our work on positional memory is now published. We asked how axolotl cells 'know' which part of the limb to regenerate after injury.
www.nature.com/articles/s41...
A joy to work with super team Sarah Plattner, Yuka Sugiura, Francisco Falcon and Elly Tanaka.
🧵1/14
www.nature.com/articles/s41...
A joy to work with super team Sarah Plattner, Yuka Sugiura, Francisco Falcon and Elly Tanaka.
🧵1/14
Reposted by Benjamin Friedrich
Die #Exzellenzcluster stehen fest: Heute hat die Exzellenzkommission 70 Projekte zur Förderung ausgewählt. 45 Cluster werden fortgesetzt, 25 neu eingerichtet. Die Förderung beginnt ab 1. Jan. 2026 für 7 Jahre, die Fördersumme beträgt insg. 539 Mio. €/Jahr. Die Liste: www.dfg.de/resource/blo... 1/3
May 22, 2025 at 3:05 PM
Die #Exzellenzcluster stehen fest: Heute hat die Exzellenzkommission 70 Projekte zur Förderung ausgewählt. 45 Cluster werden fortgesetzt, 25 neu eingerichtet. Die Förderung beginnt ab 1. Jan. 2026 für 7 Jahre, die Fördersumme beträgt insg. 539 Mio. €/Jahr. Die Liste: www.dfg.de/resource/blo... 1/3
Fully-funded PhD position at @poldresden.bsky.social in Dresden, Germany, to theoretically study sarcomere self-assembly in muscle cells, in collaboration with the experimental group of Frank Schnorrer @frankschnorrer.bsky.social
More information here:
physics-of-life.tu-dresden.de/friedrich
More information here:
physics-of-life.tu-dresden.de/friedrich
April 6, 2025 at 6:53 PM
Fully-funded PhD position at @poldresden.bsky.social in Dresden, Germany, to theoretically study sarcomere self-assembly in muscle cells, in collaboration with the experimental group of Frank Schnorrer @frankschnorrer.bsky.social
More information here:
physics-of-life.tu-dresden.de/friedrich
More information here:
physics-of-life.tu-dresden.de/friedrich
Reposted by Benjamin Friedrich
🚀 Looking for an #HFSP ally? We’ve got you covered with #AtomicForceMicroscopy, #CellCulture, #Mechanobiological #Modeling, & more! 🤝 Interested? Let’s connect! 📧 Details 👉 physics-of-life.tu-dresden.de #Collaboration
PoL – Physics of Life | Team | PoL Groups | Elisabeth Fischer-Friedrich
Physics of Life: Discover new paradigms for understanding life and deepen our knowledge of living biological matter
physics-of-life.tu-dresden.de
March 9, 2025 at 5:50 PM
🚀 Looking for an #HFSP ally? We’ve got you covered with #AtomicForceMicroscopy, #CellCulture, #Mechanobiological #Modeling, & more! 🤝 Interested? Let’s connect! 📧 Details 👉 physics-of-life.tu-dresden.de #Collaboration
Reposted by Benjamin Friedrich
It’s the #filopodia, stupid! 🚀
We just released our new study uncovering how filopodia and hydrostatic #pressure contribute to the regulation of #membrane #tension.
👉 Check it out on bioRxiv: biorxiv.org/content/10.1...
#cellbiology #biophysics #actin #mechanobiology
We just released our new study uncovering how filopodia and hydrostatic #pressure contribute to the regulation of #membrane #tension.
👉 Check it out on bioRxiv: biorxiv.org/content/10.1...
#cellbiology #biophysics #actin #mechanobiology
March 27, 2025 at 11:49 AM
It’s the #filopodia, stupid! 🚀
We just released our new study uncovering how filopodia and hydrostatic #pressure contribute to the regulation of #membrane #tension.
👉 Check it out on bioRxiv: biorxiv.org/content/10.1...
#cellbiology #biophysics #actin #mechanobiology
We just released our new study uncovering how filopodia and hydrostatic #pressure contribute to the regulation of #membrane #tension.
👉 Check it out on bioRxiv: biorxiv.org/content/10.1...
#cellbiology #biophysics #actin #mechanobiology
Reposted by Benjamin Friedrich
A fantastic collaboration between PoL members @stefandiezlab.bsky.social and @friedrich-group.bsky.social published now in @naturephysics.bsky.social - well done to all involved! 🎉🤓
Check out the official CMCB press release below:
Check out the official CMCB press release below:
⁉️ How can cilia beat rhythmically?
The Diez Lab @stefandiezlab.bsky.social and @friedrich-group.bsky.social at @poldresden.bsky.social found a twisting motion during cilia beats that might play a key role in coordinating their tiny molecular motors! 🌀⚙️
Read more ➡️ tud.link/wr8ze9
#CMCBnews
The Diez Lab @stefandiezlab.bsky.social and @friedrich-group.bsky.social at @poldresden.bsky.social found a twisting motion during cilia beats that might play a key role in coordinating their tiny molecular motors! 🌀⚙️
Read more ➡️ tud.link/wr8ze9
#CMCBnews
Verborgene Verdrillung: Forschende enthüllen die geheime Bewegung von Zilien
Spermien bewegen sich fort, indem sie ihre Geißel rhythmisch schlagen. Ähnliche Geißeln, bekannt als Zilien, finden sich auch in Zellen der Lunge und des Gehirns, wo sie Flüssigkeit durch das Gewebe …
tud.link
March 4, 2025 at 1:47 PM
A fantastic collaboration between PoL members @stefandiezlab.bsky.social and @friedrich-group.bsky.social published now in @naturephysics.bsky.social - well done to all involved! 🎉🤓
Check out the official CMCB press release below:
Check out the official CMCB press release below:
Reposted by Benjamin Friedrich
I'm looking for a talented+motivated person to join my team at the #MechanobiologyInstitute @NUS for a #postdoc. If you're interested in investigating collective cell behavior during 3D tissue #morphogenesis with me, please apply here or PM for Qs. Please RT! careers.nus.edu.sg/job/Research...
February 18, 2025 at 7:05 AM
I'm looking for a talented+motivated person to join my team at the #MechanobiologyInstitute @NUS for a #postdoc. If you're interested in investigating collective cell behavior during 3D tissue #morphogenesis with me, please apply here or PM for Qs. Please RT! careers.nus.edu.sg/job/Research...
Reposted by Benjamin Friedrich
New preprint from the lab on #coral larval light responses, including ciliary arrests and body-wide contractions.
Led by Emelie Brodrick, in collaboration with @micromotility.bsky.social
#biology #cilia @ERC_Research
#hfsp https://www.biorxiv.org/content/10.1101/2025.02.06.636794v1
Led by Emelie Brodrick, in collaboration with @micromotility.bsky.social
#biology #cilia @ERC_Research
#hfsp https://www.biorxiv.org/content/10.1101/2025.02.06.636794v1
February 7, 2025 at 10:25 AM
New preprint from the lab on #coral larval light responses, including ciliary arrests and body-wide contractions.
Led by Emelie Brodrick, in collaboration with @micromotility.bsky.social
#biology #cilia @ERC_Research
#hfsp https://www.biorxiv.org/content/10.1101/2025.02.06.636794v1
Led by Emelie Brodrick, in collaboration with @micromotility.bsky.social
#biology #cilia @ERC_Research
#hfsp https://www.biorxiv.org/content/10.1101/2025.02.06.636794v1
Preprint: How do axolotl regrow lost limbs that match the size of the organism? A model of coupled morphogen dynamics & tissue growth suggests that some morphogen parameters should scale with animal size, but stay constant during regeneration, i.e. show static scaling www.biorxiv.org/content/10.1...
February 18, 2025 at 12:43 PM
Preprint: How do axolotl regrow lost limbs that match the size of the organism? A model of coupled morphogen dynamics & tissue growth suggests that some morphogen parameters should scale with animal size, but stay constant during regeneration, i.e. show static scaling www.biorxiv.org/content/10.1...
Reposted by Benjamin Friedrich
Fantastic work done by PoL PI @fischerfriedriclab.bsky.social with the Dahmann lab, published in Development @dev-journal.bsky.social earlier this month.
Well done to all involved in this collaboration!
Well done to all involved in this collaboration!
It turns out that #EggChamber #elongation and rotation can be decoupled in #Drosophila egg chamber #morphogenesis - check out our recent collaborative work with the Dahmann lab. journals.biologists.com/dev/article/... . Congrats to Akanksha Bhatt and Valentin Ruffine 👏🥳
February 7, 2025 at 9:24 AM
Fantastic work done by PoL PI @fischerfriedriclab.bsky.social with the Dahmann lab, published in Development @dev-journal.bsky.social earlier this month.
Well done to all involved in this collaboration!
Well done to all involved in this collaboration!
Reposted by Benjamin Friedrich
We invite you to submit your latest research to our special issue - Cilia and Flagella: from Basic Biology to Disease. This issue will be coordinated by two Guest Editors: Pleasantine Mill @cilialab.bsky.social and Lotte Pedersen @lottepedersen.bsky.social.
journals.biologists.com/jcs/pages/ci...
journals.biologists.com/jcs/pages/ci...
February 6, 2025 at 10:02 AM
We invite you to submit your latest research to our special issue - Cilia and Flagella: from Basic Biology to Disease. This issue will be coordinated by two Guest Editors: Pleasantine Mill @cilialab.bsky.social and Lotte Pedersen @lottepedersen.bsky.social.
journals.biologists.com/jcs/pages/ci...
journals.biologists.com/jcs/pages/ci...
Reposted by Benjamin Friedrich
It turns out that #EggChamber #elongation and rotation can be decoupled in #Drosophila egg chamber #morphogenesis - check out our recent collaborative work with the Dahmann lab. journals.biologists.com/dev/article/... . Congrats to Akanksha Bhatt and Valentin Ruffine 👏🥳
February 4, 2025 at 2:31 PM
It turns out that #EggChamber #elongation and rotation can be decoupled in #Drosophila egg chamber #morphogenesis - check out our recent collaborative work with the Dahmann lab. journals.biologists.com/dev/article/... . Congrats to Akanksha Bhatt and Valentin Ruffine 👏🥳
Reposted by Benjamin Friedrich
📣 Excited to receive the 💥 NSF CAREER 💥 Award. Our group is looking for PhD students and postdocs interested in the Nonlinear Dynamics and the Physics of Living Systems, with support from NSF, HFSP, and other sources. We’d appreciate your help in spreading the word! @ucsdphysci.bsky.social
January 16, 2025 at 9:08 PM
📣 Excited to receive the 💥 NSF CAREER 💥 Award. Our group is looking for PhD students and postdocs interested in the Nonlinear Dynamics and the Physics of Living Systems, with support from NSF, HFSP, and other sources. We’d appreciate your help in spreading the word! @ucsdphysci.bsky.social
4 places left! Workshop "Biophysics of Motile Cilia": Topics: #axoneme mechanics, #synchronization, #navigation, #ciliopathies, ... Meet us in Bad Honnef, Germany, 30.03.-02.04.2025 www.we-heraeus-stiftung.de/veranstaltun...
January 14, 2025 at 7:15 PM
4 places left! Workshop "Biophysics of Motile Cilia": Topics: #axoneme mechanics, #synchronization, #navigation, #ciliopathies, ... Meet us in Bad Honnef, Germany, 30.03.-02.04.2025 www.we-heraeus-stiftung.de/veranstaltun...
"Biophysics of Motile Cilia" Heraeus workshop: program online! Application deadline: 12.01.25. Topics: #axoneme #synchronization #navigation #ciliopathies ... Bad Honnef, Germany, 30.03.-02.04.2025 www.we-heraeus-stiftung.de/veranstaltungen/the-biophysics-of-motile-cilia-from-structure-to-function
December 20, 2024 at 5:52 PM
"Biophysics of Motile Cilia" Heraeus workshop: program online! Application deadline: 12.01.25. Topics: #axoneme #synchronization #navigation #ciliopathies ... Bad Honnef, Germany, 30.03.-02.04.2025 www.we-heraeus-stiftung.de/veranstaltungen/the-biophysics-of-motile-cilia-from-structure-to-function