Fran Supek
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fransupek.bsky.social
Fran Supek
@fransupek.bsky.social
🧬Genetics geek, 🤖AI enthusiast. PI @GenomeDataLab studying DNA repair, mutations, epigenome & NMD. 2xERC, professor @bric-ucph.bsky.social, GL @irbbarcelona.org. 🎲Chaotic good.
🛑Guille's @guillepalou.bsky.social no-nonsense 😉 paper is out in @springernature.com Genome Biology!

We report variable activity of the NMD pathway (mRNA QC) across tissues & individuals:

🧠less active in the nervous system & in reproductive tissues
🩸more active in digestive tract, muscle, blood
September 29, 2025 at 4:54 PM
Fantastic to be in such great company!🤩

👏Congrats to 19 colleagues from my institutions (🇩🇰BRIC @UCPH_health and 🇪🇸@IRBBarcelona) in this year's Elsevier/Stanford top 2% most cited researchers list
September 28, 2025 at 6:53 PM
Congrats to our CRISPy fresh doctor 👏👏 Marcel McCullough for successfully defending his PhD thesis:

🧬✂️"Combinatorial Gene Editing in Human Cells to Model Deficiencies of DNA Repair in Cancer"

Thx to committee members Julian Ceron, Laura Valle and David Szuts for a great discussion!
July 1, 2025 at 8:04 AM
🧵 Ahmed’s @genomedatalab.bsky.social paper on evolution of chemotherapy resistance is out @natcomms.nature.com!

We developed DiffInvex - a method tracking how #cancer driver genes change under therapy using ~10k whole-genomes. Key insight: drug resistance often emerges through existing pathways 1/5
May 14, 2025 at 8:08 AM