Fran Supek
@fransupek.bsky.social
🧬Genetics geek, 🤖AI enthusiast. PI @GenomeDataLab studying DNA repair, mutations, epigenome & NMD. 2xERC, professor @bric-ucph.bsky.social, GL @irbbarcelona.org. 🎲Chaotic good.
🛑Guille's @guillepalou.bsky.social no-nonsense 😉 paper is out in @springernature.com Genome Biology!
We report variable activity of the NMD pathway (mRNA QC) across tissues & individuals:
🧠less active in the nervous system & in reproductive tissues
🩸more active in digestive tract, muscle, blood
We report variable activity of the NMD pathway (mRNA QC) across tissues & individuals:
🧠less active in the nervous system & in reproductive tissues
🩸more active in digestive tract, muscle, blood
September 29, 2025 at 4:54 PM
🛑Guille's @guillepalou.bsky.social no-nonsense 😉 paper is out in @springernature.com Genome Biology!
We report variable activity of the NMD pathway (mRNA QC) across tissues & individuals:
🧠less active in the nervous system & in reproductive tissues
🩸more active in digestive tract, muscle, blood
We report variable activity of the NMD pathway (mRNA QC) across tissues & individuals:
🧠less active in the nervous system & in reproductive tissues
🩸more active in digestive tract, muscle, blood
Fantastic to be in such great company!🤩
👏Congrats to 19 colleagues from my institutions (🇩🇰BRIC @UCPH_health and 🇪🇸@IRBBarcelona) in this year's Elsevier/Stanford top 2% most cited researchers list
👏Congrats to 19 colleagues from my institutions (🇩🇰BRIC @UCPH_health and 🇪🇸@IRBBarcelona) in this year's Elsevier/Stanford top 2% most cited researchers list
September 28, 2025 at 6:53 PM
Fantastic to be in such great company!🤩
👏Congrats to 19 colleagues from my institutions (🇩🇰BRIC @UCPH_health and 🇪🇸@IRBBarcelona) in this year's Elsevier/Stanford top 2% most cited researchers list
👏Congrats to 19 colleagues from my institutions (🇩🇰BRIC @UCPH_health and 🇪🇸@IRBBarcelona) in this year's Elsevier/Stanford top 2% most cited researchers list
Thanks to organizers for inviting!
S2.2. DNA break repair in the CRISPR era @EMBO
📢 Using combinatorial CRISPR/Cas12 edits and mutational signatures to study genetic interactions in DNA repair pathways - Fran Supek @FranSupek
#47congresosebbm
📢 Using combinatorial CRISPR/Cas12 edits and mutational signatures to study genetic interactions in DNA repair pathways - Fran Supek @FranSupek
#47congresosebbm
September 4, 2025 at 9:41 AM
Thanks to organizers for inviting!
Reposted by Fran Supek
🧬New approach to decoding mutational signatures improves prediction of prognosis in #OvarianCancer.
📰 #GenomeMedicine ✍️ Patricia Ferrer-T Iván Galván-F & @fransupek.bsky.social
➡️ bit.ly/4nA579b 📌DOI: 10.1186/s13073-025-01497-7
@genomedatalab.bsky.social @bric-ucph.bsky.social
🧪
📰 #GenomeMedicine ✍️ Patricia Ferrer-T Iván Galván-F & @fransupek.bsky.social
➡️ bit.ly/4nA579b 📌DOI: 10.1186/s13073-025-01497-7
@genomedatalab.bsky.social @bric-ucph.bsky.social
🧪
July 8, 2025 at 10:50 AM
🧬New approach to decoding mutational signatures improves prediction of prognosis in #OvarianCancer.
📰 #GenomeMedicine ✍️ Patricia Ferrer-T Iván Galván-F & @fransupek.bsky.social
➡️ bit.ly/4nA579b 📌DOI: 10.1186/s13073-025-01497-7
@genomedatalab.bsky.social @bric-ucph.bsky.social
🧪
📰 #GenomeMedicine ✍️ Patricia Ferrer-T Iván Galván-F & @fransupek.bsky.social
➡️ bit.ly/4nA579b 📌DOI: 10.1186/s13073-025-01497-7
@genomedatalab.bsky.social @bric-ucph.bsky.social
🧪
Congrats to our CRISPy fresh doctor 👏👏 Marcel McCullough for successfully defending his PhD thesis:
🧬✂️"Combinatorial Gene Editing in Human Cells to Model Deficiencies of DNA Repair in Cancer"
Thx to committee members Julian Ceron, Laura Valle and David Szuts for a great discussion!
🧬✂️"Combinatorial Gene Editing in Human Cells to Model Deficiencies of DNA Repair in Cancer"
Thx to committee members Julian Ceron, Laura Valle and David Szuts for a great discussion!
July 1, 2025 at 8:04 AM
Congrats to our CRISPy fresh doctor 👏👏 Marcel McCullough for successfully defending his PhD thesis:
🧬✂️"Combinatorial Gene Editing in Human Cells to Model Deficiencies of DNA Repair in Cancer"
Thx to committee members Julian Ceron, Laura Valle and David Szuts for a great discussion!
🧬✂️"Combinatorial Gene Editing in Human Cells to Model Deficiencies of DNA Repair in Cancer"
Thx to committee members Julian Ceron, Laura Valle and David Szuts for a great discussion!
Join us at BRIC/FinsenLab -- start your group at the University of Copenhagen!
WE ARE RECRUITING: A tenure-track group leader position in translational cancer research is available at the Finsen Laboratory in Copenhagen. Come join an excellent and friendly research environment combining both hospital and university affiliated groups
candidate.hr-manager.net/ApplicationI...
candidate.hr-manager.net/ApplicationI...
Tenure-track Research Group leader position in translational cancer research at the Finsen Laboratory, Rigshospitalet, Copenhagen University Hospital
A group leader position at the Finsen Laboratory, Rigshospitalet, Copenhagen University Hospital is open for appointment as soon as possible. The position is av
candidate.hr-manager.net
June 3, 2025 at 7:41 PM
Join us at BRIC/FinsenLab -- start your group at the University of Copenhagen!
🧵 Ahmed’s @genomedatalab.bsky.social paper on evolution of chemotherapy resistance is out @natcomms.nature.com!
We developed DiffInvex - a method tracking how #cancer driver genes change under therapy using ~10k whole-genomes. Key insight: drug resistance often emerges through existing pathways 1/5
We developed DiffInvex - a method tracking how #cancer driver genes change under therapy using ~10k whole-genomes. Key insight: drug resistance often emerges through existing pathways 1/5
May 14, 2025 at 8:08 AM
🧵 Ahmed’s @genomedatalab.bsky.social paper on evolution of chemotherapy resistance is out @natcomms.nature.com!
We developed DiffInvex - a method tracking how #cancer driver genes change under therapy using ~10k whole-genomes. Key insight: drug resistance often emerges through existing pathways 1/5
We developed DiffInvex - a method tracking how #cancer driver genes change under therapy using ~10k whole-genomes. Key insight: drug resistance often emerges through existing pathways 1/5