Francis Poulat
@francispoulat.bsky.social
Group leader at the IGH in Montpellier. Interested in sex determination and reproductive biology.
Reposted by Francis Poulat
Gonadal sex determination in vertebrates: rethinking established mechanisms
In this Review, dagmar-wilhelm.bsky.social, Marie-Christine Chaboissier & colleagues discuss mechanisms and genes currently known to be involved in sex determination and differentiation:
doi.org/10.1242/dev....
In this Review, dagmar-wilhelm.bsky.social, Marie-Christine Chaboissier & colleagues discuss mechanisms and genes currently known to be involved in sex determination and differentiation:
doi.org/10.1242/dev....
![Figure 2 Formation of the adrenal and gonadal primordia in vertebrates. (A) The adrenogonadal primordium [AGP, indicated in colour with the future adrenal primordium (AP) in pink and the future gonadal primordium (GP) in yellow] arises from lateral plate mesoderm at 9.5 days post-coitum (dpc) in mouse embryos, at HH13 (Hamburger Hamilton stage) in chicken embryos and at Carnegie stage (CS) 14 in human embryos. (B) The spatial and temporal appearances of the AP and GP vary between species, with the AP and GP being spatially, temporally and phenotypically distinct: the AP develops earlier and is clearly separated from the GP in human (left). In mouse (centre), the AGP splits into a more cranial AP, and a more caudal GP at 10.5 dpc, and in chicken (right), the AP and GP are derived from two adjacent layers of coelomic epithelium and/or the mesonephric mesenchyme. MD, mesonephric duct; MT, mesonephric tubules.](https://cdn.bsky.app/img/feed_thumbnail/plain/did:plc:btitwyhiegkb6f62oguxt6m6/bafkreiefglvka37f7mfotv6y6mtycbnemz2symhtmg4xhofmdnyy2lfl3m@jpeg)
April 2, 2025 at 8:51 AM
Gonadal sex determination in vertebrates: rethinking established mechanisms
In this Review, dagmar-wilhelm.bsky.social, Marie-Christine Chaboissier & colleagues discuss mechanisms and genes currently known to be involved in sex determination and differentiation:
doi.org/10.1242/dev....
In this Review, dagmar-wilhelm.bsky.social, Marie-Christine Chaboissier & colleagues discuss mechanisms and genes currently known to be involved in sex determination and differentiation:
doi.org/10.1242/dev....
Reposted by Francis Poulat
🔺🔺🔺RED TRIANGLE ALERT 🔺🔺🔺
Ever wonder how #TADs compare across the tree of life?Look no further & read our Review!!!
Find out what genes & 3D chromatin can & can't do in Bacteria! Archeae! Yeast! Plants! Animals!
SMCs & RNA-Pol are the only thing they have in common
www.nature.com/articles/s41...
Ever wonder how #TADs compare across the tree of life?Look no further & read our Review!!!
Find out what genes & 3D chromatin can & can't do in Bacteria! Archeae! Yeast! Plants! Animals!
SMCs & RNA-Pol are the only thing they have in common
www.nature.com/articles/s41...
Evolution and function of chromatin domains across the tree of life - Nature Structural & Molecular Biology
Szalay et al. discuss cross-kingdom similarities and differences in 3D chromatin folding in relation to gene regulation, including in bacteria, archaea, mammals and plants. This comparison reveals cer...
www.nature.com
November 28, 2024 at 12:48 PM
🔺🔺🔺RED TRIANGLE ALERT 🔺🔺🔺
Ever wonder how #TADs compare across the tree of life?Look no further & read our Review!!!
Find out what genes & 3D chromatin can & can't do in Bacteria! Archeae! Yeast! Plants! Animals!
SMCs & RNA-Pol are the only thing they have in common
www.nature.com/articles/s41...
Ever wonder how #TADs compare across the tree of life?Look no further & read our Review!!!
Find out what genes & 3D chromatin can & can't do in Bacteria! Archeae! Yeast! Plants! Animals!
SMCs & RNA-Pol are the only thing they have in common
www.nature.com/articles/s41...
when french parliament plan to tax research on mouse….sign here against : r.gircor.fr/lnk/AWUAAFk_...
Microsoft Forms
r.gircor.fr
November 28, 2024 at 1:26 PM
when french parliament plan to tax research on mouse….sign here against : r.gircor.fr/lnk/AWUAAFk_...
Reposted by Francis Poulat
"Dark TFs": new manuscript mapped 166 uncharacterized human transcription factors, finding half bind genomic "dark matter," often closed chromatin rich in transposable elements.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
November 20, 2024 at 11:20 AM
Reposted by Francis Poulat
In 2019, 70% of Republicans said science has had a mostly positive effect on society. Recently, fewer than half of Republicans (47%) said so.
www.pewresearch.org/science/2023... 🧪🌐
www.pewresearch.org/science/2023... 🧪🌐
November 24, 2024 at 11:52 PM
In 2019, 70% of Republicans said science has had a mostly positive effect on society. Recently, fewer than half of Republicans (47%) said so.
www.pewresearch.org/science/2023... 🧪🌐
www.pewresearch.org/science/2023... 🧪🌐
I think it would be important for us to influence our scientific colleagues or our respective institutes to migrate en masse to bluesky and leave X. #leaveXtoBS
November 22, 2024 at 11:24 PM
I think it would be important for us to influence our scientific colleagues or our respective institutes to migrate en masse to bluesky and leave X. #leaveXtoBS
hello bluesky , leaving the X trash, I’m interested by reproductive biology, sex determination, chromatin and all stuffs about gene regulation
November 22, 2024 at 12:34 AM
hello bluesky , leaving the X trash, I’m interested by reproductive biology, sex determination, chromatin and all stuffs about gene regulation