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Fluorochem Ltd
@fluorochemltd.bsky.social
27 followers 20 following 70 posts
Fluorochem is a leading supplier in the chemical industry, with nearly 60 years of experience supporting scientists in chemistry, pharmaceuticals and medicinal chemistry, and advanced molecular research.
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VHL ligands engage the VHL E3 ligase, a highly validated recruiter in PROTAC design, offering robust degradation profiles. Their structural diversity supports fine-tuning of ternary complex stability and pharmacological properties.

fluorochem.co.uk/product-cate...

🧪 #TargetedProteinDegradation
October 2, 2025 at 11:13 AM
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Targeted Protein Degradation

Fluorochem is here to support you as you build PROTACs or other heterobifunctional molecules with an excellent range of target-binding ligands, linkers and E3 ubiquitin ligase ligands.

🧪 #ChemicalBiology #LifeSciences #TPD

fluorochem.co.uk/product-cate...
October 1, 2025 at 2:55 PM
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Cereblon (CRBN) ligands the most extensively used ligase recruiters in targeted protein degradation. The CRL4 CRBN E3 ligase complex is recruited to tag proteins for ubiquitination & degradation. 🧪
#TargetedMedicine #MedicinalChemistry #ProteinDegradation #PharmaResearch #TranslationalResearch #TPD
September 25, 2025 at 10:05 AM
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Tertrazines are ideal for pre-targeted imaging, drug delivery, and bioorthogonal chemistry. browse our range of click chemistry reagents and much much more on our site!

#Chemistry #ClickChemistry #Imaging #MolecularBiology #MedChem
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September 23, 2025 at 10:46 AM
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There's till time to talk to our rep in Cambridge and find out how Fluorochem can support your ADC and PROTAC synthesis, library development or custom projects!🧪

#CamMedChem25 #ADC #PROTAC #Pharma #ChemSky #BioSky #AcademicSky
September 16, 2025 at 1:48 PM
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Another medicinal chemistry symposium this week! Drop by to hear the latest developments at Fluorochem and new ranges in chemical building blocks, biological reagents and complex medicinal agents like ADCs OR heterobifunctional protein degraders!

#CamMedChem25
#ADCs
#ChemSky
#AcademicSky
🧪
September 15, 2025 at 2:49 PM
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Click chemistry is ideal for fast, selective and modular reactions that simplify complex molecule assembly. In biological systems, copper free reagents are ideal - find them on our site!🧪

fluorochem.co.uk/product-cate...
#ChemSky #BioSky #Biochem #ClickChem #ClickReactions #MolecularBio #MedChem
September 11, 2025 at 1:15 PM
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How did click reactions become common practise in synthesis?
🧪

#ClickChem #Chemistry #Biochemistry #ChemSky #clickreactions #Syntheticchem
September 9, 2025 at 3:43 PM
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Find everything for chemical synthesis, delivered fast, with uncompromising quality 🚚

Click chemistry simplifies complex molecule assembly with fast, selective and modular reactions. Find click reagents & more on our site!🧪
fluorochem.co.uk/product-cate...
#ChemSky #Biochem #Synthesis #Clickchem
September 5, 2025 at 9:17 AM
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Come and speak to us about all things #peptides #smallmolecules and #medicinalchemistry at the EFMC-ASMC x International Symposium on advances in synthetic and medicinal chemistry.

#medchem #ASMC #EFMCASMC2025 #EFMC
September 2, 2025 at 8:23 AM
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Click chemistry has become a go-to strategy for fast, selective and modular reactions that simplify complex molecule assembly. 🧩

Find everything you need to assemble your molecules with Fluorochem’s high quality click reagents!🧪

#ChemSky #ClickChem #Synthesis

fluorochem.co.uk/product-cate...
August 28, 2025 at 1:06 PM
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Kinases contribute to regulation of cellular signalling and drive many diseases when dysregulated. Small molecule kinase inhibitors allow precise control over these enzymes, enabling pathway dissection, biomarker discovery and therapeutic targeting.🧪
#Kinase #MedChem
fluorochem.co.uk/product-cate...
August 27, 2025 at 8:22 AM
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Ion channels control the flow of ions across membranes, governing everything from nerve impulses to cardiac rhythms. With small molecule activators and inhibitors, researchers can modulate channel activity with precision. 🧪
#ChemSky #BioSky #MedChem #IonChannel
fluorochem.co.uk/product-cate...
August 21, 2025 at 12:29 PM
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Proteases are involved in processes like immunity, cancer progression, and viral replication. Small molecule protease inhibitors help control these enzymes with high specificity, useful in both research and therapeutic applications. 🧪
fluorochem.co.uk/product-cate...
#SMI #protease #ChemSky #cancer
August 14, 2025 at 11:21 AM
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GPCRs are highly druggable yet complex. Fluorochem’s small molecules, including agonists & antagonists, help tune signalling processes, study ligand-receptor interactions & explore disease pathways. Perfect tools for #Biochem #DrugDiscovery #MedChem #Protein #Signalling research!
Selection of structures and product details of GPCR modulators available in the Fluorochem catalogue.
August 7, 2025 at 12:08 PM
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Phase Transfer Catalysts 🧪

Transporting reaction components between phases, our phase-transfer catalysts efficiently accelerate synthetic and industrial processes while improving solvent economy.

#ChemSky #LabLife #OrgChem #OrganicChemistry #SustainableChemistry

fluorochem.co.uk/product-cate...
July 31, 2025 at 11:19 AM
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Find transition-metal complexes to catalyse molecular remodelling. Fluorochem’s selection covers heavy-hitting stalwarts like Grubbs, precious metal catalysts including palladium and gold and powerful complexes using earth abundant metals.🧪
#ChemSky #Catalysts #Metal #Catalysis #AcademicSky
July 28, 2025 at 8:34 AM
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Speak to Fluorochem at the 28th International Symposium: Synthesis in Organic Chemistry.
Find out how we can support your #synthesis or #medchem with our extensive range of building blocks, synthesis reagents, #NMR solvents or #photochemistry.
#AcademicSky #Conference #ChemSky #orgchem
July 23, 2025 at 1:11 PM
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Organocatalysts

Offering greener methods, while still producing excellent chemical results including highly selective asymmetric catalysis, Fluorochem’s organocatalysts promote countless chemical reactions.

fluorochem.co.uk/product-cate...

#ChemSky #Biosky #catalysts #organocatalyst 🧪
July 17, 2025 at 11:07 AM
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Come and speak to us today if you're at the Chemistry symposium @ucl.ac.uk and find out how Fluorochem can support your research far beyond fluorinated compounds

#ChemSky #ucl #AcademicSky #chemistry #research 🧪
A table of orange chemistry themed merchandise including brochures about small molecule inhibitors and squishy conical flasks. The back ground is 2 banners with the Fluorochem logo and info graphics about our service
June 26, 2025 at 9:06 AM
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Protected amino acids - these protected forms ensure controlled stepwise synthesis, for application in solid-phase peptide synthesis (SPPS) or solution-phase methods.

Premium amino acids provide the consistency and performance your science demands.

#aminoacids #peptidesynthesis #ChemSky 🧪
June 19, 2025 at 1:19 PM
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Peptide synthesis and amide bond formation are essential techniques in chemical biology.

Coupling reagents like COMU, HBTU, and HATU high efficiency, low racemization, and broad substrate compatibility make them go-to tools in both academic and industrial labs.

🧪 #ChemSky #Peptide #Biochem
June 12, 2025 at 4:02 PM
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Peptides have wide applications in modern medicine and drug discovery, diagnostics and biological research. They are versatile enough to function as selective therapeutics, biomarkers and high-specificity probes in biological assays. 🧪

#ChemSky #BioSky #Peptides #Research #Benchwork
June 5, 2025 at 1:05 PM
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Organoboron Building Blocks 🧪

Widely used as cross-coupling partners to rapidly assemble more complex molecules, boronic acids and their derivatives have been reliable features of medicinal chemistry, materials science and general synthesis for decades.

#ChemSky #ScienceSky #SyntheticChem #Pharma
May 22, 2025 at 10:03 AM
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Ethanol is present in alcoholic beverages of all kinds enjoyed by humans and, it transpires, wild chimpanzees (Pan troglodytes verus)! They've been reported to eat and share fermented African Breadfruit (Treculia africana).

Cheers! 🧪

www.cell.com/current-biol...

#AcademicSky #BioSky #ZooSky
May 20, 2025 at 4:07 PM