Florentin Lab
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florentin-lab.bsky.social
Florentin Lab
@florentin-lab.bsky.social
Parasites, education, global health and all-things-science. The Florentin lab studies the cell biology of malaria parasites, while surviving everything else. https://www.florentinlab.com/
Pinned
Please check Amanda’s new publication, fresh on PLOS Pathogens! 😀👩‍🔬🧪🧬
Read & learn about organelle proteostasis in malaria parasites -
An apicoplast-biogenesis mutant that dies on the first cycle🩸
BIG complexes and drug targets 💊💉
journals.plos.org/plospathogen...
A chaperonin complex regulates organelle proteostasis in malaria parasites
Author summary The cell of the human malaria parasite Plasmodium falciparum has a unique organelle called the apicoplast that produces essential metabolites, but it is unclear how it maintains a stabl...
journals.plos.org
Please check Amanda’s new publication, fresh on PLOS Pathogens! 😀👩‍🔬🧪🧬
Read & learn about organelle proteostasis in malaria parasites -
An apicoplast-biogenesis mutant that dies on the first cycle🩸
BIG complexes and drug targets 💊💉
journals.plos.org/plospathogen...
A chaperonin complex regulates organelle proteostasis in malaria parasites
Author summary The cell of the human malaria parasite Plasmodium falciparum has a unique organelle called the apicoplast that produces essential metabolites, but it is unclear how it maintains a stabl...
journals.plos.org
August 25, 2025 at 1:46 PM
Reposted by Florentin Lab
🚨 New preprint alert! 🚨
We’ve uncovered a key player in malaria parasite cell division—meet PfAnchor, the first apicoplast-specific dynamin adaptor protein! Check the thread below 🧵for more details. #U_ExM #Malaria #Apicoplast
www.biorxiv.org/content/10.1...
An Essential Adaptor for Apicoplast Fission and Inheritance in Malaria Parasites
Blood-stage Plasmodium falciparum parasites rely on a non-photosynthetic plastid, the apicoplast, for survival, making it an attractive target for antimalarial intervention. Like the mitochondrion, th...
www.biorxiv.org
April 14, 2025 at 7:45 PM
What an interesting and personal reflection of women, science and society. And how about the yet-unfulfilled role of women in conflict resolution? One must fight for better days
Bluetorial: Women, courage, and leadership

What follows will include some generalizations based on population averages of what I have experienced over the course of my career. There are, of course, exceptions in every group who are substantially more to one extreme or the other.
a cartoon says hey everybody an old man 's talking while bart simpson looks on
ALT: a cartoon says hey everybody an old man 's talking while bart simpson looks on
media.tenor.com
March 9, 2025 at 7:05 PM
Another exciting preprint from our new lab‼️
Are you interested in Parasites 🦠 + Organelle biology 🧪+ Microscopy 🔬+ Cell Cycle 🧬?!
How could one not be?! 👩‍🔬
Check out, read & comment and wish us good luck with the long way ahead towards publication…
www.biorxiv.org/content/10.1...
Organelle Development and Inheritance are Driven by Independent Nuclear and Organellar Mechanisms in Malaria Parasites
The apicoplast organelle of Plasmodium falciparum is essential for parasite replication, however the details of its biogenesis, inheritance and regulation throughout the cell cycle are unknown. Here, ...
www.biorxiv.org
March 9, 2025 at 1:39 PM
Reposted by Florentin Lab
The MPM XXXVI page is now live. Sept 14th to Sept 18th. More updates will be coming soon. Check it out on the parasitesrule.com website. Organized this year by Richarch McCulloch @rmc9z.bsky.social, Photini Sinnis, Marc-Jan Gubbels, Deepali Ravel & Omar Harb @omarharb.bsky.social
Molecular Parasitology Community
The MPM XXXVI website is now online
parasitesrule.com
January 21, 2025 at 4:47 PM
Reposted by Florentin Lab
Registration for the 2nd WiM online conference is now OPEN, everyone can register: womeninmalaria.es/wim-conferen...

There is a fee waiver application for LMICs & also an option to buy fee waivers for others during the registration process 🧫🧬🦟 Please share!
December 26, 2024 at 11:46 AM
Reposted by Florentin Lab
People sometimes make fun of science that sounds stupid and random.

Meanwhile, a study of lizard saliva turned into a peptide medication, which was turned into a diabetes medication, which was turned into a GLP1 weight loss drug, that just became the first therapy every approved for … sleep apnea
Breaking News: The FDA approved use of the weight loss drug Zepbound for a common form of sleep apnea. It is the first drug authorized to treat the disorder.
F.D.A. Approves Weight-Loss Drug to Treat Sleep Apnea
Zepbound is the first prescription drug approved specifically to treat the common condition.
www.nytimes.com
December 21, 2024 at 12:41 AM
Reposted by Florentin Lab
I am looking for an ERC-funded postdoc to work on spatial proteomics of microalgae (red algae and glaucophytes). The ideal candidate will have experience with mass spec and data analysis (R), but above all a keen interest in broad eukaryote evolution and protists #protistsonsky (1/2)
December 10, 2024 at 7:42 AM
Reposted by Florentin Lab
A thread of 9(!!) #Parasitology-based, funded PhD opportunities from the EastBio doctoral training programme at Edinburgh Uni listed below! The projects include #malaria/#Plasmodium, #trypanosoma, #leishmania, #toxoplasma, and #helminths! All deadlines are the 17th January 2025!
December 10, 2024 at 4:33 PM
😆 Hyperexcited to see the program!
Interested in apicomplexan parasites? 🔬What a lineup of speakers👩‍⚕️👨‍🔬 + registration is affordable 💰 and low on carbon footprint 👣 apicomplexaconference.com
Apicomplexa-2025 – Apicomplexan Parasites Virtual Symposium | Jan 22-23, 2025
apicomplexaconference.com
December 7, 2024 at 1:24 PM
Beware - this angry bird (sorry, parasite!) is looking your way
(blue nuclei, yellow apicoplast, red cytoplasm)
November 24, 2024 at 6:20 PM
Hey likeminded colleagues with high standards and low budget! Looking for a super-fun, low-cost lab social activity? Our paint-your-lab-coat-day was a HUGE SUCCESS:
November 23, 2024 at 2:10 PM
Motivated🙋, kind🥰 and hardworking👩‍⚕️, Amanda's and Shirly's joint STEP scholarship is well-deserved! 🔬🥼. The Science Training Encouraging Peace program funds pairs of Israeli and Palestinian students 👩‍❤️‍💋‍👩 Do you also feel that any positive news could be nice? 👇👇👇
blogs.timesofisrael.com/malaria-rese...
Malaria research in Israel?! You read that right!
From the blog of Kobi Russell at The Times of Israel
blogs.timesofisrael.com
November 23, 2024 at 1:52 PM
Is there a single molecule ⚛️ linking malaria to high blood pressure??? ⚕️📢💉👨‍🔬 Happy to work with and learn from lab trainee Dr. Hari Shankar 🤩 Together, we thought, explored and investigated concepts that are pretty distinct from our daily lab work🔬:
sciencedirect.com/science/arti...
Hepcidin: A missing link at the interface of malaria and hypertension
Malaria and hypertension are seemingly unrelated communicable and non-communicable diseases, both highly pervasive in the global south. There is a deb…
sciencedirect.com
November 23, 2024 at 1:31 PM
🚨🖨️👩‍🔬New Preprint alert! Please have a look to learn about organelle proteostasis in malaria parasites🩸 An apicoplast-biogenesis mutant that dies☠️on the first cycle! 🧪🦟So proud in 1st author Amanda Tissawak for the first major research article from our lab!
www.biorxiv.org/content/10.1...
A Chaperonin Complex Regulates Organelle Proteostasis in Malaria Parasites
The apicoplast of Plasmodium parasites serves as a metabolic hub that synthesize essential biomolecules. Like other endosymbiotic organelles, 90% of the apicoplast proteome is encoded by the cell nucl...
www.biorxiv.org
November 23, 2024 at 1:22 PM