For the aficionados: we find that 3 statin molecules bind per subunit of RyR1 (12 for a full tetramer). The statins also interact with one another, highlighting an unusual binding mode.

Work spearheaded by Steven Molinarolo.

Special thanks to people at our in-house EM facility
@hrmem.bsky.social

Hope this isn't going to apply to anyone already on H-1B, but only future ones.

unconscious bias...

seems you can definitely forget about BLAST with an entire RyR sequence...

hopefully not a symptom of funding cuts and resignations at NIH

an invitation to talk on the Galapagos Islands?

seconding this. It also applies to presentations. The perfect way to throw off your audience is to use highly specific jargon and acronyms to an audience that is not (fully) in your field

#CryoEM