Fakun Cao
@fakuncao.bsky.social
Reposted by Fakun Cao
Excited to share our paper out now in @science.org . We (@mpiib-berlin.mpg.de ) engineered single-component signalosomes to dissect the biophysical properties required for signaling. Read on for a cool story on using #synthetic-biology to study #signaling. 1/10
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
Bottom-up reconstruction of functional death fold signalosomes reveals a requirement for polymer stability and avidity
Protein polymer scaffolds composed of death fold (DF) proteins are critical to the formation of signalosomes in immune signaling. The biophysical properties that these polymeric scaffolds require for ...
www.science.org
April 25, 2025 at 7:10 AM
Excited to share our paper out now in @science.org . We (@mpiib-berlin.mpg.de ) engineered single-component signalosomes to dissect the biophysical properties required for signaling. Read on for a cool story on using #synthetic-biology to study #signaling. 1/10
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...